Study protocol of SWEPIS a Swedish multicentre register based randomised controlled trial to compare induction of labour at 41 completed gestational weeks versus expectant management and induction at 42 completed gestational weeks.

Research output: Contribution to journalArticle


Observational data shows that postterm pregnancy (≥42 gestational weeks, GW) and late term pregnancy (≥41 GW), as compared to term pregnancy, is associated with an increased risk for adverse outcome for the mother and infant. Standard care in many countries is induction of labour at 42 GW. There is insufficient scientific support that induction of labour at 41 GW, as compared with expectant management and induction at 42 GW will reduce perinatal mortality and morbidity without an increase in operative deliveries, negative delivery experiences or higher costs. Large randomised studies are needed since important outcomes; such as perinatal mortality and hypoxic ischaemic encephalopathy are rare events.


  • Helen Elden
  • Henrik Hagberg
  • Anna Wessberg
  • Verena Sengpiel
  • Andreas Herbst
  • Maria Bullarbo
  • Christina Bergh
  • Kristian Bolin
  • Snezana Malbasic
  • Sissel Saltvedt
  • Olof Stephansson
  • Anna-Karin Wikström
  • Lars Ladfors
  • Ulla-Britt Wennerholm
External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Obstetrics, Gynecology and Reproductive Medicine
Original languageEnglish
Article number49
JournalBMC Pregnancy and Childbirth
Issue number1
Publication statusPublished - 2016
Publication categoryResearch
Externally publishedYes