Temporary in situ aluminum and zinc tethering in Diels-Alder reactions

Research output: Contribution to journalArticle

Abstract

(formula presented) Temporary tethering using aluminum or zinc in Diels-Alder reactions made possible the use of otherwise "noncompatible" combinations of dienes and dienophiles, resulting in the one-step formation of substituted cyclohexene 1,2-bis-methanols. Excellent regioselectivity and also significant stereoselectivity were obtained.

Details

Authors
Organisations
External organisations
  • ACADIA Pharmaceuticals Inc.
  • ACADIA Pharmaceuticals A/S
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Pharmaceutical Sciences
Original languageEnglish
Pages (from-to)1283-1286
JournalOrganic Letters
Volume2
Issue number9
Publication statusPublished - 2000 Apr 8
Publication categoryResearch
Peer-reviewedYes