TERT promoter mutations: a novel independent prognostic factor in primary glioblastomas.

Research output: Contribution to journalArticle

Abstract

Activating somatic mutations in the promoter region of the telomerase reverse transcriptase gene (TERT) have been detected in several cancers. In this study we investigated the TERT promoter mutations and their impact on patient survival in World Health Organization grade IV glioblastoma multiforme (GBM).

Details

Authors
  • Matthias Simon
  • Ismail Hosen
  • Konstantinos Gousias
  • Sivaramakrishna Rachakonda
  • Barbara Heidenreich
  • Marco Gessi
  • Johannes Schramm
  • Kari Hemminki
  • Andreas Waha
  • Rajiv Kumar
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Public Health, Global Health, Social Medicine and Epidemiology
Original languageEnglish
Pages (from-to)45-52
JournalNeuro-Oncology
Volume17
Issue number1
Publication statusPublished - 2015
Publication categoryResearch
Peer-reviewedYes

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