The Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.

Research output: Contribution to journalArticle

Abstract

Observational studies show an association between ferritin and type 2 diabetes (T2D), suggesting a role of high iron stores in T2D development. However, ferritin is influenced by factors other than iron stores, which is less the case for other biomarkers of iron metabolism. We investigate associations of ferritin, transferrin saturation (TSAT), serum iron, and transferrin with T2D incidence to clarify the role of iron in the pathogenesis of T2D.

Details

Authors
  • Clara Podmore
  • Karina Meidtner
  • Matthias B Schulze
  • Robert A Scott
  • Anna Ramond
  • Adam S Butterworth
  • Emanuele Di Angelantonio
  • John Danesh
  • Larraitz Arriola
  • Aurelio Barricarte
  • Heiner Boeing
  • Françoise Clavel-Chapelon
  • Amanda J Cross
  • Christina C Dahm
  • Guy Fagherazzi
  • Diana Gavrila
  • Sara Grioni
  • Marc J Gunter
  • Gaelle Gusto
  • Paula Jakszyn
  • Verena Katzke
  • Timothy J Key
  • Tilman Kühn
  • Amalia Mattiello
  • Anja Olsen
  • Kim Overvad
  • Domenico Palli
  • J Ramón Quirós
  • Olov Rolandsson
  • Carlotta Sacerdote
  • Emilio Sánchez-Cantalejo
  • Nadia Slimani
  • Ivonne Sluijs
  • Annemieke M W Spijkerman
  • Anne Tjonneland
  • Rosario Tumino
  • Daphne L van der A
  • Yvonne T van der Schouw
  • Edith J M Feskens
  • Nita G Forouhi
  • Stephen J Sharp
  • Elio Riboli
  • Claudia Langenberg
  • Nicholas J Wareham
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Endocrinology and Diabetes
Original languageEnglish
Pages (from-to)572-581
Number of pages9
JournalDiabetes Care
Volume39
Issue number4
Early online date2016 Feb 9
Publication statusPublished - 2016 Apr
Publication categoryResearch
Peer-reviewedYes