The Central Role of Bcl-3 in Atopic Dermatitis

Research output: Contribution to journalDebate/Note/Editorial

Abstract

Cytokines and hormones are essential mediators in the regulation of antimicrobial peptide and protein (AMP) levels during host defense responses. In this issue, Buchau et al. identify and characterize B-cell leukemia-3 as an important modulator of AMP expression during the innate immune response in keratinocytes as well as in the chronic inflammatory skin disorder atopic dermatitis.

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Authors
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Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases

Keywords

  • Proto-Oncogene Proteins: physiology, Vitamin D: administration & dosage, Keratinocytes: immunology, Transcription Factors: physiology, Atopic: therapy, Dermatitis, Atopic: immunology, Atopic: etiology, Antimicrobial Cationic Peptides: genetics, Antimicrobial Cationic Peptides: physiology
Original languageEnglish
Pages (from-to)2088-2090
JournalJournal of Investigative Dermatology
Volume129
Issue number9
Publication statusPublished - 2009
Publication categoryResearch
Peer-reviewedNo