The clinical significance of 10-m walk test standardizations in Parkinson’s disease

Research output: Contribution to journalArticle


Background: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson’s disease (PD). However, it is unclear if different standardizations of its conduct impact test results. Aim of the study: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall prediction were also explored. Methods: 151 people with PD (mean age and PD duration, 68 and 4 years, respectively) completed the 10MWT in comfortable gait speed with static and dynamic start (two trials each), and gait speed (m/s) was recorded. Participants then registered all prospective falls for 6 months. Results: Absolute mean differences between outcomes from the various test conditions ranged between 0.016 and 0.040 m/s (effect sizes, 0.06–0.14) with high levels of agreement (intra-class correlation coefficients, 0.932–0.987) and small standard errors of measurement (0.032–0.076 m/s). Receiver operating characteristic curves showed similar discriminate abilities for prediction of future falls across conditions (areas under curves, 0.70–0.73). Cut-off points were estimated at 1.1–1.2 m/s. Conclusions: Different 10MWT standardizations yield very similar results, suggesting that there is no practical need for an acceleration distance or repeated trials when conducting this test in mild PD.


External organisations
  • Skåne University Hospital
  • Kristianstad University
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Neurology


  • Falls, Parkinson disease, Prediction, Test standardization, The 10-m walk test
Original languageEnglish
Pages (from-to)1829-1835
JournalJournal of Neurology
Issue number8
Early online date2018 Jun 6
Publication statusPublished - 2018
Publication categoryResearch