The effect of endovascular aortic stents placed across the renal arteries

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To investigate renal artery patency and renal function after deployment of aortic stents covering the orifices of renal arteries. DESIGN: Prospective open animal study. SETTING: Department of Experimental Surgery at a university hospital. MATERIALS: Twenty-three pigs were used. METHODS: Ten pigs were observed for 1 h after graft-anchoring aortic stents, Gianturco (5) and Palmaz (5), were placed so that the stents covered the renal arterial orifices. In 13 pigs, Gianturco (6) and Palmaz (7) stents without grafts were placed over the renal arteries and left in situ for 7 days. Renal function and blood flow were measured by renograms, iohexol clearance and ultrasonic blood flow meter and patency was verified by angiograms. The kidneys were microscopically examined for signs of ischaemia and microemboli. RESULTS: One renal artery covered by a graft-anchoring Gianturco stent occluded. The remaining renal arteries remained patent without any significant decrease in renal blood flow after stent deployment. Normal renal function and histology was maintained. CONCLUSIONS: Aortic stents placed at the level of the renal arteries do not affect renal blood flow within 1 week in this experimental model. This may prove valuable in endovascular treatment of aortic aneurysms and in other procedures involving stents.

Details

Authors
  • Martin Malina
  • Mats Lindh
  • Krassi Ivancev
  • Bo Frennby
  • Bengt Lindblad
  • Jan Brunkwall
Organisations
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Surgery

Keywords

  • Aortic aneurysm, Endovascular treatment, Stent, Renal artery obstruction, Renal blood flow
Original languageEnglish
Pages (from-to)207-213
JournalEuropean Journal of Vascular and Endovascular Surgery
Volume13
Issue number2
Publication statusPublished - 1997
Publication categoryResearch
Peer-reviewedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200), Medical Radiology Unit (013241410), Unit for Clinical Vascular Disease Research (013242410)