The lectin complement pathway serine proteases (MASPs) represent a possible crossroad between the coagulation and complement systems in thromboinflammation.
Research output: Contribution to journal › Article
The activated forms of the complement lectin pathway (LP) proteases MASP-1 and -2 are able to cleave the coagulation factors prothrombin, fibrinogen, factor XIII and TAFI in vitro. In vivo studies also show that MASP-1 is involved in thrombogenesis, OBJECTIVES: To clarify the not yet identified mechanisms involved in triggering activation of the LP during thrombotic reactions.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Thrombosis and Haemostasis|
|Early online date||2015 Nov 28|
|Publication status||Published - 2016|