The macrophage migration inhibitory factor MIF is a phenylpyruvate tautomerase
Research output: Contribution to journal › Article
A macrophage migration inhibitory factor (MIF), originally described as a product of activated lymphocytes, has been defined as a 12 kDa protein, expressed in a wide variety of tissues. Here MIF is identified as a phenylpyruvate tautomerase (EC 220.127.116.11) having p-hydroxyphenylpyruvate and phenylpyruvate as its natural substrates. The definition of MIF as an enzyme may yield insight into the mechanism of action of this proinflammatory and immunomodulating cytokine.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Publication status||Published - 1997|
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200), Department of Dermatology and Venereology (Lund) (013006000), Department of Experimental Medical Science (013210000)