The molecular clutch model for mechanotransduction evolves

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The molecular clutch model for mechanotransduction evolves. / Swaminathan, Vinay; Waterman, Clare M.

In: Nature Cell Biology, Vol. 18, No. 5, 27.04.2016, p. 459-61.

Research output: Contribution to journalReview article

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Swaminathan, Vinay ; Waterman, Clare M. / The molecular clutch model for mechanotransduction evolves. In: Nature Cell Biology. 2016 ; Vol. 18, No. 5. pp. 459-61.

RIS

TY - JOUR

T1 - The molecular clutch model for mechanotransduction evolves

AU - Swaminathan, Vinay

AU - Waterman, Clare M

PY - 2016/4/27

Y1 - 2016/4/27

N2 - Many biological processes are influenced by the mechanical rigidity of surrounding tissues. Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.

AB - Many biological processes are influenced by the mechanical rigidity of surrounding tissues. Now, a combination of experiments and mathematical modelling has been used to describe the precise molecular and physical mechanism by which cells sense and respond to the mechanical properties of their extracellular environment through integrin-based adhesions.

KW - Integrins

KW - Mechanotransduction, Cellular

U2 - 10.1038/ncb3350

DO - 10.1038/ncb3350

M3 - Review article

VL - 18

SP - 459

EP - 461

JO - Nature Cell Biology

T2 - Nature Cell Biology

JF - Nature Cell Biology

SN - 1465-7392

IS - 5

ER -