The new cell irradiation facility at the Lund nuclear probe
Research output: Contribution to journal › Article
The CELLION project is directed towards the studies on cellular response to targeted single ions. This paper gives an account of the modifications made at the Lund sub-micron beam line in order to create a Single Ion Hit Facility for biological applications within the CELLION project. The most relevant new feature is the specially developed software used to locate the cells. A program for cell recognition and localization that gives the coordinates of the centre of the cells has been designed. The recognition is made online. A picture taken by a microscope is used as input parameter for the recognition program. Using V79 Chinese hamster cells, the recognition procedure can be done in less than 0.5 s for a picture size of 800 x 600 pixels with approximately 96% efficiency. This paper also reports target accuracy test results and the first non-targeted irradiation procedure performed at the Lund sub-micron beam line. (c) 2007 Elsevier B.V. All rights reserved.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Nuclear Instruments & Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms|
|Publication status||Published - 2007|
|Event||10th International Conference on Nuclear Microprobe Technology and Applications and 2nd International Workshop on Proton Beam Writing - Singapore, Singapore|
Duration: 2006 Jul 9 → 2006 Jul 14
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Nuclear Physics (Faculty of Technology) (011013007), Division of Infection Medicine (BMC) (013024020)
Related research output
Single-Proton Irradiation of Living Cells - Development of New Tools for Low-Dose Radiation ResearchNatalia Arteaga, 2010, Department of Physics, Lund University. 133 p.
Research output: Thesis › Doctoral Thesis (compilation)