The Potential of MicroRNAs as Prostate Cancer Biomarkers.

Research output: Contribution to journalReview article

Abstract

Short noncoding RNAs known as microRNAs (miRNAs) control protein expression through the degradation of RNA or the inhibition of protein translation. The miRNAs influence a wide range of biologic processes and are often deregulated in cancer. This family of small RNAs constitutes potentially valuable markers for the diagnosis, prognosis, and therapeutic choices in prostate cancer (PCa) patients, as well as potential drugs (miRNA mimics) or drug targets (anti-miRNAs) in PCa management.

Details

Authors
  • Linda Fabris
  • Yvonne Ceder
  • Arul M Chinnaiyan
  • Guido W Jenster
  • Karina D Sorensen
  • Scott Tomlins
  • Tapio Visakorpi
  • George A Calin
Organisations
External organisations
  • University of Texas
  • University of Michigan
  • Erasmus University Medical Center
  • Aarhus University Hospital
  • Tampere University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Urology and Nephrology
Original languageEnglish
Pages (from-to)312-322
JournalEuropean Urology
Volume70
Issue number2
Early online date2016 Jan 21
Publication statusPublished - 2016
Publication categoryResearch
Peer-reviewedYes