The reactivity of the back revisited. Are there differences in reactivity in different parts of the back?

Research output: Contribution to journalArticle


Background: In the contact dermatitis literature, it is regularly stated that the patch test reactivity on various areas of the back differs; this might have a large impact on the reproducibility of patch testing. Objectives: To investigate the reproducibility of patch testing on the upper back with regard to the left as opposed to the right side and the medial as opposed to the lateral part of the upper back. The reproducibility over time and with regard to the reactivity pattern was also investigated. Methods: Thirty-one subjects with contact allergy to the metals gold (n=19) or nickel (n=12) were patch tested with serial dilutions, in triplicate applications, on different locations on the upper back. The Friedman test was used for statistical calculations. Results: No significant differences in the reactivity of the back were found. In all gold-allergic patients and 11 of 12 nickel-allergic patients, the allergy could be reproduced with regard to previous patch testing, but the degree of reactivity differed. Conclusions: When a high level of standardization of the patch test technique with the same test system was used, there were no differences in patch test reactions and sites of application on the upper back.


External organisations
  • Skåne University Hospital
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases


  • Anatomical site, Angry back, Contact allergy, Excited skin syndrome, Patch test, Reactivity, Reproducibility, Serial dilution
Original languageEnglish
Pages (from-to)19-26
JournalContact Dermatitis
Issue number1
Publication statusPublished - 2017 Jan
Publication categoryResearch

Related research output

Björk, A-K., 2017, Lund: Lund University: Faculty of Medicine.

Research output: ThesisDoctoral Thesis (compilation)

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