The significance of bicuspid aortic valve after surgery for acute type A aortic dissection

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: Decision-making concerning the extent of the repair of acute type A aortic dissection (ATAAD) includes functional and anatomical assessment of the aortic valve. We hypothesized that bicuspid aortic valve (BAV) does not impact outcome after surgery for ATAAD. We therefore evaluated the outcome after ATAAD surgery in relation to the presence of BAV, acute aortic regurgitation (AR), and surgical approach, using the Nordic Consortium for Acute Type A Aortic Dissection database.

METHODS: Eight participating Nordic centers collected data from 1122 patients undergoing ATAAD surgery during the years 2005 to 2014. Early complications, reoperations and survival were compared between patients with BAV and tricuspid aortic valves (TAV) before and after propensity score matching for sex, age, AR, organ malperfusion, hemodynamic instability, and site of the tear. Mean follow-up (range) for patients with TAV and BAV was 3.1 years (0-10.4 years) and 3.2 years (0-9.0 years), respectively.

RESULTS: Altogether, 65 (5.8%) of the patients had BAV. Root replacement was more frequently performed in the BAV as compared with the TAV group (60% vs 23%, P < .001). Survival, however, did not differ significantly between patients with BAV or TAV, either before (P = .230) or after propensity score-matching (P = .812). Even so, in cohort as a whole, patients presenting with AR had less favorable survival.

CONCLUSIONS: Early and mid-term survival did not differ significantly between patients with BAV and TAV.

Details

Authors
  • Ari Mennander
  • Christian Olsson
  • Anders Jeppsson
  • Arnar Geirsson
  • Vibeke Hjortdal
  • Emma C Hansson
  • Kati Jarvela
  • Shahab Nozohoor
  • Jarmo Gunn
  • Anders Ahlsson
  • Tomas Gudbjartsson
Organisations
External organisations
  • Karolinska University Hospital
  • Aarhus University Hospital
  • University of Tampere
  • University of Gothenburg
  • Skåne University Hospital
  • Turku University Hospital
  • Örebro University Hospital
  • National University Hospital of Iceland
  • University of Iceland
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Cardiac and Cardiovascular Systems
Original languageEnglish
JournalThe Journal of thoracic and cardiovascular surgery
Publication statusE-pub ahead of print - 2019 Mar 21
Publication categoryResearch
Peer-reviewedYes