The Swedish National Pediatric Cataract Register (PECARE): incidence and onset of postoperative glaucoma

Research output: Contribution to journalArticle

Bibtex

@article{75cb81256921435081b4322a2cd93553,
title = "The Swedish National Pediatric Cataract Register (PECARE): incidence and onset of postoperative glaucoma",
abstract = "Purpose: The aim was to report cumulative incidence and time of onset of postoperative glaucoma in a paediatric early cataract surgery cohort. Methods: Data were retrieved from the Pediatric Cataract Register (PECARE), a prospective register of Swedish cataract operations before 8 years of age. All eyes with surgery between January 2007 and December 2014 and a registered follow-up were included. Cataracts caused by uveitis, trauma or coexisting congenital glaucoma were excluded. Glaucoma was defined as early onset if diagnosed within a year after surgery and late onset if diagnosed later. Results: The study included 288 eyes in 207 children (106 girls), 81 with bilateral and 126 with unilateral cataracts, with a mean follow-up of 3.31 ± 1.77 years. Of the 288, 168 (58.3{\%}) had surgery before 3 months of age; most of these 92.3{\%} (155/168) were defined as dense, 208 (72.2{\%}) were below 1 year of age. Cumulative incidence of surgically treated glaucoma among individuals was 23.7{\%} (49/207). Median time to glaucoma onset was 0.91 years (range: 0.05–4.97 years) for eyes. Early-onset glaucoma was found in 98 {\%} (63/64), and late onset in 2{\%} (1/64). Conclusion: In this paediatric cataract cohort, a majority of eyes had surgery before 3 months of age (58.3{\%}). Secondary glaucoma-onset peaked within the first postoperative year, with a cumulative incidence of 23.7{\%}. Surgery performed after the first month of life, resulted in a lower glaucoma rate. Long-term follow-up will reveal whether the low rate of late-onset glaucoma with early surgery will last, and if so, the consequences.",
keywords = "glaucoma incidence, glaucoma onset, paediatric cataract surgery, postoperative glaucoma, registry data",
author = "Alf Nystr{\"o}m and Birgitte Haargaard and Annika Rosensv{\"a}rd and Kristina Tornqvist and Gunilla Magnusson",
year = "2020",
month = "4",
day = "9",
doi = "10.1111/aos.14414",
language = "English",
journal = "Acta Ophthalmologica",
issn = "1755-3768",
publisher = "Wiley-Blackwell",

}