Time trends in Swedish patch test data from 1992 to 2000. A multi-centre study based on age-adjusted and sex-adjusted results of the Swedish standard series

Research output: Contribution to journalArticle


Allergic contact dermatitis is recognized as a public health problem and some major allergens have been subject to intervention aiming at lowering skin exposure. There is an obvious interest in evaluating the effect of such interventions. Population studies are difficult to perform and epidemiological studies based on clinical data from testing patients with contact dermatitis are common surrogates. Our objective was to gather Swedish clinical standard series test data on two occasions in order to monitor trends in sensitization rates. Consecutive patch test results from the Swedish standard series were collected from 9 centres from 1991 to 1993 and from 1999 to 2001. In total, 3680 and 3790 patients, respectively, were included. Crude, age-adjusted and age-stratified prevalence are given separately for women and men. Our top 10 allergens are much in line with newly published European test data. Significant changes among those allergens are increasing sensitization rates for Myroxylon pereirae and decreasing rates for colophony, 5-chloro-2-methyl-4-isothiazolin-3-one, Amerchol L 101 and thiuram mix. Nickel allergy is decreasing among young women. Among less common allergens, a noteworthy increase of sensitization to 4-phenylendiamine is found. In conclusion, significant trends in sensitization rates of important allergen, reflecting changes in exposure, have been found.


  • Magnus Lindberg
  • Björn Edman
  • Torkel Fischer
  • Berndt Stenberg
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Dermatology and Venereal Diseases


  • time trends, sensitization rate, patch test data, clinical data, epidemiological surveillance
Original languageEnglish
Pages (from-to)205-210
JournalContact Dermatitis
Issue number4
Publication statusPublished - 2007
Publication categoryResearch

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venerology (013241320), Pediatrics/Urology/Gynecology/Endocrinology (013240400)