Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting

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Bibtex

@article{fc4ac0ee9aed4de190d37c62f5a77de6,
title = "Towards global consensus on outcome measures for atopic eczema research: results of the HOME II meeting",
abstract = "The use of nonstandardized and inadequately validated outcome measures in atopic eczema trials is a major obstacle to practising evidence-based dermatology. The Harmonising Outcome Measures for Eczema (HOME) initiative is an international multiprofessional group dedicated to atopic eczema outcomes research. In June 2011, the HOME initiative conducted a consensus study involving 43 individuals from 10 countries, representing different stakeholders (patients, clinicians, methodologists, pharmaceutical industry) to determine core outcome domains for atopic eczema trials, to define quality criteria for atopic eczema outcome measures and to prioritize topics for atopic eczema outcomes research. Delegates were given evidence-based information, followed by structured group discussion and anonymous consensus voting. Consensus was achieved to include clinical signs, symptoms, long-term control of flares and quality of life into the core set of outcome domains for atopic eczema trials. The HOME initiative strongly recommends including and reporting these core outcome domains as primary or secondary endpoints in all future atopic eczema trials. Measures of these core outcome domains need to be valid, sensitive to change and feasible. Prioritized topics of the HOME initiative are the identification/development of the most appropriate instruments for the four core outcome domains. HOME is open to anyone with an interest in atopic eczema outcomes research.",
keywords = "atopic dermatitis, consensus study, measurement, outcome domain, study, endpoint",
author = "Jochen Schmitt and Phyllis Spuls and Maarten Boers and Kim Thomas and Joanne Chalmers and Evelien Roekevisch and Mandy Schram and Richard Allsopp and Valeria Aoki and Christian Apfelbacher and Carla Bruijnzeel-Koomen and Marjolein Bruin-Weller and Carolyn Charman and Arnon Cohen and Magdalene Dohil and Carsten Flohr and Masutaka Furue and Uwe Gieler and Lotty Hooft and Rosemary Humphreys and Ishii, {Henrique Akira} and Ichiro Katayama and Willem Kouwenhoven and Sinead Langan and Sue Lewis-Jones and Stephanie Merhand and Hiroyuki Murota and Murrell, {Dedee F.} and Helen Nankervis and Yukihiro Ohya and Arnold Oranje and Hiromi Otsuka and Carle Paul and Yael Rosenbluth and Hidehisa Saeki and Marie-Louise Schuttelaar and Jean-Francois Stalder and {\AA}ke Svensson and Roberto Takaoka and Carl-Fredrik Wahlgren and Stephan Weidinger and Andreas Wollenberg and Hywel Williams",
note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venerology (013241320)",
year = "2012",
doi = "10.1111/j.1398-9995.2012.02874.x",
language = "English",
volume = "67",
pages = "1111--1117",
journal = "Allergy",
issn = "1398-9995",
publisher = "Wiley-Blackwell",
number = "9",

}