Trust in genomic data sharing among members of the general public in the UK, USA, Canada and Australia

Research output: Contribution to journalArticle


Trust may be important in shaping public attitudes to genetics and intentions to participate in genomics research and big data initiatives. As such, we examined trust in data sharing among the general public. A cross-sectional online survey collected responses from representative publics in the USA, Canada, UK and Australia (n = 8967). Participants were most likely to trust their medical doctor and less likely to trust other entities named. Company researchers were least likely to be trusted. Low, Variable and High Trust classes were defined using latent class analysis. Members of the High Trust class were more likely to be under 50 years, male, with children, hold religious beliefs, have personal experience of genetics and be from the USA. They were most likely to be willing to donate their genomic and health data for clinical and research uses. The Low Trust class were less reassured than other respondents by laws preventing exploitation of donated information. Variation in trust, its relation to areas of concern about the use of genomic data and potential of legislation are considered. These findings have relevance for efforts to expand genomic medicine and data sharing beyond those with personal experience of genetics or research participants.


External organisations
  • University of Cambridge
  • RAND corporation
  • King's College London
  • University of Melbourne
  • Uppsala University
  • University of Tasmania
  • Swinburne University of Technology
  • University of Vienna
  • Murdoch Children's Research Institute
  • Catholic University of Leuven
  • Wellcome Trust Sanger Institute
  • University of Suffolk, UK
  • Ontario Institute for Cancer Research
  • McGill University
  • Wellcome Trust Genome Campus
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Social Sciences
  • Medical Genetics


  • Data sharing, Donation, Genome, Public, Survey, Trust
Original languageEnglish
Pages (from-to)1237-1246
Number of pages10
JournalHuman Genetics
Issue number11-12
Publication statusPublished - 2019 Dec 1
Publication categoryResearch
Externally publishedYes