Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.

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Abstract

Numerous studies have been performed aimed at limiting the extent of retinal injury after ischemia, but there is still no effective pharmacological treatment available. The aim of the present study was to examine the role of tumor necrosis factor (TNF)α and its receptors (TNF-R1 and TNF-R2), especially considering the neuroretina and the retinal vasculature since the retinal blood vessels are key organs in circulatory failure.

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  • Biochemistry and Molecular Biology
Original languageEnglish
Pages (from-to)2317-2327
JournalMolecular Vision
Volume16
Publication statusPublished - 2010
Publication categoryResearch
Peer-reviewedYes