Ultrasonographic risk score of carotid plaques

Research output: Contribution to journalArticle

Abstract

OBJECTIVE: to determine the relative significance of ultrasonographic parameters of carotid plaques to develop an Activity Index (AI) which could correlate with clinical findings. METHOD: two hundred and fifteen plaques in 141 patients underwent ultrasonography and computer-assisted structural analysis. In half the patients (group 1), plaques were classified as either homogeneous and heterogeneous and ultrasonographic appearances related symptomatic (SP) or asymptomatic (AP) station. The probability of SP for each ultrasound parameter was used to define an Activity Index (AI). The AI was then applied the second half of patients (Group 2) to assess the value of AI in determining symptomatic station. RESULTS: the parameters with highest morbility were surface disruption, severe stenosis and low grey scale median and, additionally in heterogenous plaques heterogeneity and the presence of a juxta-luminal echolucent area. The power in group 2 of AI to identify symptomatic plaques was determined. Mean AI was for SP-75 (41-100) and for AP-43 (22-100); 78% of SP have AI>60 and 70% of AP have AI<50. The cut-off point between the two groups was 52. ROC curve analysis of the AI were obtained to determine its diagnostic accuracy. CONCLUSION: Activity Index is an objective parameter of plaque echostructure that positively correlates with symptoms. AI may contribute to better selection for treatment of patients with carotid artery disease.

Details

Authors
  • L M Pedro
  • J Fernandes e Fernandes
  • M M Pedro
  • I Goncalves
  • Nuno Dias
  • R Fernandes e Fernandes
  • T F Carneiro
  • C Balsinha
External organisations
  • Instituto Cardiovascular De Lisboa
Research areas and keywords

Subject classification (UKÄ) – MANDATORY

  • Surgery
  • Cardiac and Cardiovascular Systems
Original languageEnglish
Pages (from-to)492-498
JournalEuropean Journal of Vascular and Endovascular Surgery
Volume24
Issue number6
Publication statusPublished - 2002
Publication categoryResearch
Peer-reviewedYes
Externally publishedYes

Bibliographic note

The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Emergency medicine/Medicine/Surgery (013240200)