Unilateral denervation of the rat urinary bladder and reinnervation: a predominance for ipsilateral changes

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Bibtex

@article{a1ddb064ad614752bf53d87ca4ce9999,
title = "Unilateral denervation of the rat urinary bladder and reinnervation: a predominance for ipsilateral changes",
abstract = "Unilateral removal of the pelvic ganglion affected the bladder-half on the denervated side more profoundly than that on the non-denervated side. At an early stage (3-7 days) the former was heavier, had a lower choline acetyltransferase activity, developed less tension to nerve stimulation and, in course of time, became more sensitized to methacholine in vitro than the latter. At a late stage (30-60 days) the nerve-evoked contractile responses on the denervated side had increased, which was almost wholly attributed to the atropine-sensitive part of the contraction, but the recovery was not complete. On the non-denervated side the nerve-evoked responses were not significantly changed. It was calculated that in the normally innervated bladders 25-30% of the cholinergic nerves of each half were of contralateral origin. The figure was lower (18%) for the nerves mediating the atropine-resistant response.",
author = "J Ekstrom and Lars Malmberg and S Oberg",
year = "1986",
language = "English",
volume = "127",
pages = "223--231",
journal = "Acta Physiologica",
issn = "1748-1716",
publisher = "Wiley-Blackwell",
number = "2",

}