Vakuumassisterad sår- behandling ger goda kliniska resultat God läkning vid komplicerade sår--djupa sternuminfektioner ett exempel.

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T1 - Vakuumassisterad sår- behandling ger goda kliniska resultat God läkning vid komplicerade sår--djupa sternuminfektioner ett exempel.

AU - Sjögren, Johan

AU - Gustafsson, Ronny

AU - Lindstedt Ingemansson, Sandra

AU - Malmsjö, Malin

AU - Mokhtari, Arash

AU - Ingemansson, Richard

PY - 2008

Y1 - 2008

N2 - acuum-assisted closure (V.A.C.®) is a novel treatment for wound healing, which has been used extensively during the last years in a growing number of clinical applications. This wound-healing technique is based on the application of local negative pressure to a wound. During treatment with vacuum-assisted closure, several beneficial wound healing mechanisms are initiated. Topical negative pressure increases the microvascular blood flow in the surrounding tissue and reduces wound tissue oedema and wound size. Furthermore, the stimulation of growth factors and neoangiogenesis facilitates the formation of granulation tissue in the wound. Vacuum-assisted closure has been widely adopted as a standard treatment for deep sternal wound infections following cardiac surgery since topical negative pressure combines several advantageous features from conventional surgical techniques. However, although it is effective, vacuum-assisted closure must always be used in combination with proper surgical revision and adequate antibiotic therapy in order to obtain optimal results.

AB - acuum-assisted closure (V.A.C.®) is a novel treatment for wound healing, which has been used extensively during the last years in a growing number of clinical applications. This wound-healing technique is based on the application of local negative pressure to a wound. During treatment with vacuum-assisted closure, several beneficial wound healing mechanisms are initiated. Topical negative pressure increases the microvascular blood flow in the surrounding tissue and reduces wound tissue oedema and wound size. Furthermore, the stimulation of growth factors and neoangiogenesis facilitates the formation of granulation tissue in the wound. Vacuum-assisted closure has been widely adopted as a standard treatment for deep sternal wound infections following cardiac surgery since topical negative pressure combines several advantageous features from conventional surgical techniques. However, although it is effective, vacuum-assisted closure must always be used in combination with proper surgical revision and adequate antibiotic therapy in order to obtain optimal results.

KW - Osteomyelitis: microbiology

KW - Osteomyelitis: therapy

KW - Surgical Wound Infection: microbiology

KW - Thoracic Surgical Procedures: adverse effects

KW - Surgical Wound Infection: therapy

KW - Cardiac Surgical Procedures: adverse effects

KW - Negative-Pressure Wound Therapy: methods

M3 - Artikel i vetenskaplig tidskrift

VL - 105

SP - 2773

EP - 2776

JO - Läkartidningen

T2 - Läkartidningen

JF - Läkartidningen

SN - 0023-7205

IS - 40

ER -