Who let the dogs out?: detrimental role of Galectin-3 in hypoperfusion-induced retinal degeneration.
Research output: Contribution to journal › Article
Retinal ischemia results in a progressive degeneration of neurons and a pathological activation of glial cells, resulting in vision loss. In the brain, progressive damage after ischemic insult has been correlated to neuroinflammatory processes involving microglia. Galectin-3 has been shown to mediate microglial responses to ischemic injury in the brain. Therefore, we wanted to explore the contribution of Galectin-3 (Gal-3) to hypoperfusion-induced retinal degeneration in mice.
|Research areas and keywords||
Subject classification (UKÄ) – MANDATORY
|Journal||Journal of Neuroinflammation|
|Publication status||Published - 2015|