Brain Repair and Imaging in Neural Systems (BRAINS)

Organisation: forskargrupp

Fler filtreringsmöjligheter
  1. 2019
  2. Enhanced Dopamine in Prodromal Schizophrenia (EDiPS): a new animal model of relevance to schizophrenia

    Petty, A., Cui, X., Tesiram, Y., Deniz Kirik, Howes, O. & Eyles, D., 2019, I : npj Schizophrenia. 5, 1, 6.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. How is alpha-synuclein cleared from the cell?

    Stefanis, L., Emmanouilidou, E., Pantazopoulou, M., Deniz Kirik, Vekrellis, K. & Tofaris, G. K., 2019, I : Journal of Neurochemistry.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  4. 2018
  5. In vivo quantification of glial activation in minipigs overexpressing human α-synuclein

    Lillethorup, T. P., Glud, A. N., Landeck, N., Alstrup, A. K. O., Jakobsen, S., Vang, K., Doudet, D. J., Brooks, D. J., Deniz Kirik, Hinz, R., Sørensen, J. C. & Landau, A. M., 2018, I : Synapse. 72, 12, e22060.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. Longitudinal monoaminergic PET imaging of chronic proteasome inhibition in minipigs

    Lillethorup, T. P., Glud, A. N., Alstrup, A. K. O., Noer, O., Nielsen, E. H. T., Schacht, A. C., Landeck, N., Deniz Kirik, Orlowski, D., Sørensen, J. C. H., Doudet, D. J. & Landau, A. M., 2018, I : Scientific Reports. 8, 1, 15715.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Pre- and postsynaptic dysregulation of dopamine signalling in Parkinson's disease

    Gurdal Sahin, 2018, Lund: Lund University, Faculty of Medicine. 96 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  8. Quantification of Total and Mutant Huntingtin Protein Levels in Biospecimens Using a Novel alphaLISA Assay

    Baldo, B., Sajjad, M. U., Rachel Y. Cheong, Bigarreau, J., Vijayvargia, R., McLean, C., Perrier, A. L., Seong, I. S., Halliday, G., Åsa Petersén & Deniz Kirik, 2018, I : eNeuro. 5, 4

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. 2017
  10. Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates

    Mandel, R. J., Marmion, D. J., Deniz Kirik, Chu, Y., Heindel, C., McCown, T., Gray, S. J. & Kordower, J. H., 2017 jun 16, I : Acta neuropathologica communications. 5, 1, s. 47

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. Toxic effects of human and rodent variants of alpha-synuclein in vivo

    Landeck, N., Buck, K. & Deniz Kirik, 2017 feb 1, I : European Journal of Neuroscience. 45, 4, s. 536-547 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Gene therapy for Parkinson's disease: Disease modification by GDNF family of ligands

    Deniz Kirik, Cederfjäll, E., Halliday, G. & Petersén, 2017 jan 1, I : Neurobiology of Disease. 97, s. 179-188 10 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  13. Multibiometric multivoxel mr spectroscopy for distinction between brain tumours

    Durmo F., Rydelius A., S., E., S., K., S.C., B., Askaner K., Lätt J., Bengzon J., E., E., Björkman-Burtscher I. & Pia Maly Sundgren, 2017, I : Neuroradiology. 59, Suppl 1, s. S40-S41

    Forskningsoutput: TidskriftsbidragPublicerat konferensabstract

  14. 2016
  15. How can rAAV-α-synuclein and the fibril α-synuclein models advance our understanding of Parkinson's disease?

    Volpicelli-Daley, L. A., Deniz Kirik, Stoyka, L. E., Standaert, D. G. & Harms, A. S., 2016 okt 1, I : Journal of Neurochemistry. 139, S1, s. 131-155 25 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  16. A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein

    Landeck, N., Hall, H., Ardah, M. T., Majbour, N. K., El-Agnaf, O. M. A., Halliday, G. & Deniz Kirik, 2016 aug 22, I : Molecular Neurodegeneration. 11, 1, 125.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. Assessment of brain metabolite correlates of AAV-mediated overexpression of human alpha-synuclein in cortical neurons by in vivo(1) H-MR spectroscopy at 9.4 T.

    Cuellar-Baena, S., Landeck, N., Sonnay, S., Buck, K., Mlynarik, V., René in 't Zandt & Deniz Kirik, 2016, I : Journal of Neurochemistry. 137, 5, s. 806-819

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. Neurochemical Signatures for the Evaluation of Disease State and Therapeutic Strategies in Neurodegenerative Diseases: a Magnetic Resonance Spectroscopy Study

    Cuellar-Baena, S., 2016, Lund: Lund University, Faculty of Medicine. 101 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  19. Pathogenic effects of alpha-synuclein: modifications and toxicity

    Landeck, N., 2016, Lund: Lund University, Faculty of Medicine. 121 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  20. 2015
  21. A doctor's dilemma

    Deniz Kirik & Pain, E., 2015 nov 20, I : Science (New York, N.Y.). 350, 6263, s. 998

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Controlled striatal DOPA production from a gene delivery system in a rodent model of Parkinson's disease.

    Cederfjäll, E., Broom, L. & Deniz Kirik, 2015, I : Molecular Therapy. 23, 5, s. 896-906

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue.

    Rana Soylu, Adlesic, N., Baldo, B., Deniz Kirik & Åsa Petersén, 2015, I : Scientific Reports. 5, 14598.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. Overexpression of α-synuclein in oligodendrocytes does not increase susceptibility to focal striatal excitotoxicity.

    Kuzdas-Wood, D., Fellner, L., Premstaller, M., Borm, C., Bloem, B., Deniz Kirik, Wenning, G. K. & Stefanova, N., 2015, I : BMC Neuroscience. 16, 1, 86.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and function.

    Buck, K., Landeck, N., Ulusoy, A., Majbour, N. K., El-Agnaf, O. M. A. & Deniz Kirik, 2015, I : Neurobiology of Disease. 78, Mar 25, s. 100-114

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1.

    Laurent Roybon, Mastracci, T. L., Li, J., Stott, S., Leiter, A. B., Sussel, L., Brundin, P. & Jia-Yi Li, 2015, I : PLoS ONE. 10, 6, e0128035.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells.

    Fasching, L., Kapopoulou, A., Sachdeva, R., Petri, R., Marie Jönsson, Männe, C., Turelli, P., Jern, P., Cammas, F., Trono, D. & Johan Jakobsson, 2015, I : Cell Reports. 10, 1, s. 20-28

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. Volumetric analysis of the hypothalamus in Huntington Disease using 3T MRI: the IMAGE-HD Study.

    Sanaz Gabery, Georgiou-Karistianis, N., Hult Lundh, S., Rachel Cheong, Churchyard, A., Chua, P., Stout, J. C., Egan, G. F., Deniz Kirik & Åsa Petersén, 2015, I : PLoS ONE. 10, 2, e0117593.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. 2014
  30. Differential Dopamine Receptor Occupancy Underlies L-DOPA-Induced Dyskinesia in a Rat Model of Parkinson's Disease.

    Gurdal Sahin, Thompson, L., Lavisse, S., Özgür, M., Rbah-Vidal, L., Dollé, F., Hantraye, P. & Deniz Kirik, 2014, I : PLoS ONE. 9, 3, e90759.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity.

    Marco Ledri, Grönning Madsen, M., Nikitidou, L., Deniz Kirik & Merab Kokaia, 2014, I : Journal of Neuroscience. 34, 9, s. 3364-3377

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. Heat Shock Protein 70 Reduces alpha-Synuclein-Induced Predegenerative Neuronal Dystrophy in the alpha-Synuclein Viral Gene Transfer Rat Model of Parkinson's Disease

    Moloney, T. C., Hyland, R., O'Toole, D., Paucard, A., Deniz Kirik, O'Doherty, A., Gorman, A. M. & Dowd, E., 2014, I : CNS Neuroscience & Therapeutics. 20, 1, s. 50-58

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson's disease.

    Hall, H., Reyes, S., Landeck, N., Bye, C., Leanza, G., Double, K., Thompson, L., Halliday, G. & Deniz Kirik, 2014, I : Brain. 137, Jul 24, s. 2493-2508

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Novel strategies for enzyme replacement with gene therapy in models of Parkinson’s disease

    Cederfjäll, E., 2014, Brain Repair and Imaging in Neural Systems (BRAINS). 140 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  35. Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.

    Fredrik Berglind, Marco Ledri, Sørensen, A. T., Nikitidou, L., Melis, M., Bielefeld, P., Deniz Kirik, Deisseroth, K., My Andersson & Merab Kokaia, 2014, I : Neurobiology of Disease. 65, s. 133-141

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. Twisting mice move the dystonia field forward

    Åsa Petersén & Deniz Kirik, 2014, I : Journal of Clinical Investigation. 124, 7, s. 2848-2850

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  37. 2013
  38. Animal Models of Parkinson's Disease: Limits and Relevance to Neuroprotection Studies

    Bezard, E., Yue, Z., Deniz Kirik & Spillantini, M. G., 2013, I : Movement Disorders. 28, 1, s. 61-70

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  39. A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP.

    Christian Hansen, Tomas Björklund, Petit, G., Lundblad, M., Murmu, R., Brundin, P. & Jia-Yi Li, 2013, I : Neurobiology of Disease. 56C, April,30, s. 145-155

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  40. Boosting chaperone-mediated autophagy in vivo mitigates alpha-synuclein-induced neurodegeneration

    Xilouri, M., Brekk, O. R., Landeck, N., Pitychoutis, P. M., Papasilekas, T., Papadopoulou-Daifoti, Z., Deniz Kirik & Stefanis, L., 2013, I : Brain. 136, s. 2130-2146

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. Characterization of cognitive deficits in rats overexpressing human alpha-synuclein in the ventral tegmental area and medial septum using recombinant adeno-associated viral vectors.

    Hall, H., Jewett, M., Landeck, N., Nilsson, N., Schagerlöf, U., Leanza, G. & Deniz Kirik, 2013, I : PLoS ONE. 8, 5, e64844.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. Cholinergic and dopaminergic aspects of dementia in Parkinson's disease: postmortem neuropathological findings and modeling of cognitive dysfunction in rodents

    Hall, H., 2013, Brain Repair and Imaging in Neural Systems (BRAINS). 158 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  43. Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease.

    Cederfjäll, E., Nilsson, N., Gurdal Sahin, Chu, Y., Nikitidou, E., Tomas Björklund, Kordower, J. H. & Deniz Kirik, 2013, I : Scientific Reports. 3, 2157.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. Direct intranigral administration of an ubiquitin proteasome system inhibitor in rat: Behavior, positron emission tomography, immunohistochemistry

    Mackey, S., Jing, Y., Flores, J., Dinelle, K. & Doudet, D. J., 2013, I : Experimental Neurology. 247, s. 19-24

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  45. LAMP2A as a therapeutic target in Parkinson disease

    Xilouri, M., Brekk, O. R., Deniz Kirik & Stefanis, L., 2013, I : Autophagy. 9, 12, s. 2166-2168

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  46. Ser129D mutant alpha-synuclein induces earlier motor dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's disease

    Febbraro, F., Gurdal Sahin, Farran, A., Soares, S., Jensen, P. H., Deniz Kirik & Romero-Ramos, M., 2013, I : Neurobiology of Disease. 56, s. 47-58

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. The behavioural and neuropathological impact of intranigral AAV-alpha-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats

    Mulcahy, P., O'Doherty, A., Paucard, A., O'Brien, T., Deniz Kirik & Dowd, E., 2013, I : Behavioural Brain Research. 243, s. 6-15

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. Thyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents.

    Berglind Jonsdottir, Cecilia K Andersson, Annelie Carlsson, Delli, A., Forsander, G., Ludvigsson, J., Marcus, C., Samuelsson, U., Ortqvist, E., Åke Lernmark, Ivarsson, S-A. & Larsson, H. E., 2013, I : Diabetologia. 56, 8, s. 1735-1742

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. Transduced Wild-Type but Not P301S Mutated Human Tau Shows Hyperphosphorylation in Transgenic Mice Overexpressing A30P Mutated Human Alpha-Synuclein

    Oksman, M., Wisman, L., Jiang, H., Miettinen, P., Deniz Kirik & Tanila, H., 2013, I : Neurodegenerative Diseases. 12, 2, s. 91-102

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  50. Triple specificity of ZnT8 autoantibodies in relation to HLA and other islet autoantibodies in childhood and adolescent type 1 diabetes.

    Andersson, C., Vaziri Sani, F., Delli, A., Lindblad, B., Annelie Carlsson, Forsander, G., Ludvigsson, J., Marcus, C., Samuelsson, U., Ivarsson, S., Åke Lernmark, Larsson, H. E. & Study Group, T. B., 2013, I : Pediatric Diabetes. 14, 2, s. 97-105

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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