Experimentell demensforskning

Organisation: forskargrupp

Fler filtreringsmöjligheter
  1. 2020
  2. Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons

    Oxana Klementieva, Sandt, C., Isak Martinsson, Kansiz, M., Gunnar Keppler Gouras & Borondics, F., 2020 feb 7, I : Advanced Science. 9 s., 1903004.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies

    Pomeshchik, Y., Klementieva, O., Gil, J., Martinsson, I., Hansen, M. G., de Vries, T., Sancho-Balsells, A., Russ, K., Savchenko, E., Collin, A., Vaz, A. R., Bagnoli, S., Nacmias, B., Rampon, C., Sorbi, S., Brites, D., Marko-Varga, G., Kokaia, Z., Rezeli, M., Gouras, G. K. & 1 andra, Laurent Roybon, 2020, I : Stem Cell Reports. 15, 1, s. 256-273 18 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. 2019
  5. Aging, metabolism, synaptic activity, and Aβ in Alzheimer's disease

    Gunnar K. Gouras, 2019 jan 1, I : Frontiers in Aging Neuroscience. 10, JUL, 185.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  6. APP depletion alters selective pre- and post-synaptic proteins

    Isak Martinsson, Capetillo-Zarate, E., Faideau, M., Willén, K., Esteras, N., Frykman, S., Tjernberg, L. O. & Gunnar K. Gouras, 2019, I : Molecular and Cellular Neuroscience. 95, s. 86-95 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. On the Nature of β-Amyloid at Synapses

    Isak Martinsson, 2019, Lund: Lund University: Faculty of Medicine. 83 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  8. Poly(propylene imine) dendrimers with histidine-maltose shell as novel type of nanoparticles for synapse and memory protection.

    Aso, E., Isak Martinsson, Appelhans, D., Effenberg, C., Benseny-Cases, N., Gunnar Gouras, Ferrer, I. & Oxana Klementieva, 2019, I : Nanomedicine: Nanotechnology, Biology, and Medicine. s. 198-209

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. 2018
  10. Nano-scale Infrared Imaging of β-sheet Structures in Synaptic Junctions of Primary Neurons Isolated from Transgenic Mice

    O. Klementieva, Mathurin, J., A. Engdahl, Freitas, R., Willen, K., P. Uvdal, Miller, L. M. & G. Gouras, 2018 okt 29, 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018. IEEE Computer Society, Vol. 2018-September. 8510376

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

  11. Prion-like seeding and nucleation of intracellular amyloid-β

    Tomas T. Olsson, Oxana Klementieva & Gunnar K. Gouras, 2018 maj 1, I : Neurobiology of Disease. 113, s. 1-10 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease

    Wang, C., Iashchishyn, I. A., Pansieri, J., Nyström, S., Oxana Klementieva, Kara, J., Horvath, I., Moskalenko, R., Rofougaran, R., Gunnar Gouras, Kovacs, G. G., Shankar, S. K. & Morozova-Roche, L. A., 2018, I : Scientific Reports. 8, 1, 12836.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. 2017
  14. 3D membrane segmentation and quantification of intact thick cells using cryo soft X-ray transmission microscopy: A pilot study

    Cárdenes, R., Zhang, C., Oxana Klementieva, Werner, S., Guttmann, P., Pratsch, C., Cladera, J. & Bijnens, B. H., 2017 apr 1, I : PLoS ONE. 12, 4, e0174324.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease

    Takahashi, R. H., Nagao, T. & Gunnar K. Gouras, 2017 apr 1, I : Pathology International. 67, 4, s. 185-193 9 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  16. Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP

    O. Klementieva, Willén, K., I. Martinsson, B. Israelsson, A. Engdahl, Cladera, J., P. Uvdal & G. K. Gouras, 2017 mar 13, I : Nature Communications. 8, 14726.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A

    Willén, K., Edgar, J. R., Hasegawa, T., Tanaka, N., Futter, C. E. & Gunnar K Gouras, 2017, I : Molecular Neurodegeneration. 12, 61.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses

    Willén, K., Sroka, A., Takahashi, R. H. & Gunnar K. Gouras, 2017, I : Journal of Alzheimer's Disease. 60, 2, s. 511-524 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Involvement of endosomal and synaptic Aβ in models of Alzheimer's disease.

    Willén, K., 2017, Lund: Lund University: Faculty of Medicine. 80 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  20. 2016
  21. The endocytic pathway in microglia during health, aging and Alzheimer's disease

    Solé-Domènech, S., Cruz, D. L., Capetillo-Zarate, E. & Maxfield, F. R., 2016 dec 1, I : Ageing Research Reviews. 32, s. 89-103 15 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  22. Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease

    Beckelman, B. C., Day, S., Zhou, X., Donohue, M., Gunnar K. Gouras, Klann, E., Keene, C. D. & Ma, T., 2016 sep 6, I : Journal of Alzheimer's Disease. 54, 2, s. 669-678 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. Brain activity and Alzheimer's disease: A complex relationship

    Oskar Hansson & Gunnar Gouras, 2016 aug 1, I : Brain. 139, 8, s. 2109-2110 2 s.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  24. Direct High Affinity Interaction between Aβ42 and GSK3α Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer's Disease?

    Dunning, C., McGauran, G., Willén, K., Gunnar Gouras, O'Connell, D. J. & Linse, S., 2016, I : ACS Chemical Neuroscience. 7, 2, s. 161-170

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. 2015
  26. A cell culture model for monitoring α-synuclein cell-to-cell transfer.

    Reyes, J. F., Tomas Olsson, Lamberts, J. T., Devine, M. J., Kunath, T. & Brundin, P., 2015, I : Neurobiology of Disease. 77, Jul 16, s. 266-275

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. ADAM10 and BACE1 are localized to synaptic vesicles.

    Lundgren, J. L., Ahmed, S., Schedin-Weiss, S., Gunnar Gouras, Winblad, B., Tjernberg, L. O. & Frykman, S., 2015, I : Journal of Neurochemistry. 135, 3, s. 606-615

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular beta amyloid accumulation.

    Edgar, J. R., Willén, K., Gouras, G. K. & Futter, C. E., 2015, I : Journal of Cell Science. 128, 14, s. 2520-2528

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. β-amyloid Peptides and Amyloid Plaques in Alzheimer's Disease.

    Gunnar Gouras, Tomas Olsson & Oskar Hansson, 2015, I : Neurotherapeutics. 12, 1, s. 3-11

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  30. 2014
  31. Detection of pre-plaque amyloid aggregation using FTIR

    Oxana Klementieva, Anders Engdahl, Faideau, M., Willén, K., Per Uvdal & Gunnar Keppler Gouras, 2014 jul 1, I : Alzheimer's and Dementia. 10, 4

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. Activity-independent release of the amyloid β-peptide from rat brain nerve terminals.

    Lundgren, J. L., Ahmed, S., Winblad, B., Gunnar Gouras, Tjernberg, L. O. & Frykman, S., 2014, I : Neuroscience Letters. 566, Mar 3, s. 125-130

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. Glutamine Synthetase Stability and Subcellular Distribution in Astrocytes are Regulated by G-Aminobutyric Type B Receptors.

    Huyghe, D., Nakamura, Y., Terunuma, M., Faideau, M., Haydon, P., Pangalos, N. M. & Stephen, M. J., 2014, I : Journal of Biological Chemistry. 289, 42, s. 28808-28815

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

    George, S., Rönnbäck, A., Gunnar Gouras, Petit, G., Grueninger, F., Winblad, B., Graff, C. & Brundin, P., 2014, I : Acta neuropathologica communications. 2, 1, 17.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. The Inside-Out Amyloid Hypothesis and Synapse Pathology in Alzheimer's Disease.

    Gunnar Gouras, Willén, K. & Faideau, M., 2014, I : Neurodegenerative Diseases. 13, 2-3, s. 142-146

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. 2013
  37. Accumulation of Intraneuronal beta-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses

    Takahashi, R. H., Capetillo-Zarate, E., Lin, M. T., Milner, T. A. & Gunnar Gouras, 2013, I : PLoS ONE. 8, 1

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. mTOR: at the crossroads of aging, chaperones, and Alzheimer's disease.

    Gunnar Gouras, 2013, I : Journal of Neurochemistry. 124, 6, s. 747-748

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  39. 2012
  40. Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice

    Dumont, M., Stack, C., Elipenahli, C., Jainuddin, S., Gerges, M., Starkova, N., Calingasan, N. Y., Yang, L., Tampellini, D., Starkov, A. A., Chan, R. B., Di Paolo, G., Pujol, A. & Beal, M. F., 2012, I : Human Molecular Genetics. 21, 23, s. 5091-5105

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. Critical role of intraneuronal A beta in Alzheimer's disease: Technical challenges in studying intracellular A beta

    Gunnar Gouras, Willén, K. & Tampellini, D., 2012, I : Life Sciences. 91, 23-24, s. 1153-1158

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. Intraneuronal A beta Accumulation, Amyloid Plaques, and Synapse Pathology in Alzheimer's Disease

    Capetillo-Zarate, E., Gracia, L., Tampellini, D. & Gunnar Gouras, 2012, I : Neurodegenerative Diseases. 10, 1-4, s. 56-59

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Pathology of Synapses and Dendritic Spines

    Knafo, S., Gunnar Gouras, Yan, X-X. & Spires-Jones, T., 2012, I : Journal of Neural Transplantation & Plasticity. 972432.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  44. 2011
  45. Analysis of vesicular trafficking in primary neurons by live imaging.

    Tampellini, D. & Gunnar Gouras, 2011, I : Methods in Molecular Biology. 793, s. 343-350

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils

    Capetillo-Zarate, E., Gracia, L., Yu, F., Banfelder, J. R., Lin, M. T., Tampellini, D. & Gunnar Gouras, 2011, I : American Journal of Pathology. 179, 5, s. 2551-2558

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. Impaired β-Amyloid Secretion in Alzheimer's Disease Pathogenesis.

    Tampellini, D., Rahman, N., Linell, M., Capetillo-Zarate, E. & Gunnar Gouras, 2011, I : The Journal of neuroscience. 31, 43, s. 15384-15390

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. 2008
  49. Oral teriflunomide in patients with relapsing multiple sclerosis: baseline clinical features of patients in the TEMSO phase III trial

    O'Connor, P., Confavreux, C., Comi, G., Kappos, L., Wolinsky, J., Tomas Olsson, Miller, A. & Freedman, M. S., 2008, I : Multiple Sclerosis Journal. 14, s. S85-S85

    Forskningsoutput: TidskriftsbidragPublicerat konferensabstract

  50. 2004
  51. Development and Characterization of a Global Brain Ischemia Model in the Mouse -A Genetic and Pharmacological Approach

    Tomas Olsson, 2004, Division IV. 143 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  52. 1990
  53. Lack of glutathione transferase activity in intermittent claudication

    H Pessah-Rasmussen, Stavenow, L., Seidegard, J., Solem, J. O. & B Israelsson, 1990 apr 1, I : International Angiology. 9, 2, s. 70-4

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift