Experimentell demensforskning

Organisation: forskargrupp

Fler filtreringsmöjligheter
  1. 2021
  2. Differential seeding and propagating efficiency of α-synuclein strains generated in different conditions

    Di Liu, Jian Jun Guo, Ji Hui Su, Alexander Svanbergsson, Lin Yuan, Caroline Haikal, Wen Li, Gunnar Gouras & Jia Yi Li, 2021 dec, I: Translational Neurodegeneration. 10, 20.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. Up-regulation of APP endocytosis by neuronal aging drives amyloid dependent-synapse loss

    Tatiana Burrinha, Isak Martinsson, Ricardo Gomes, Ana Paula Terrasso, Gunnar K Gouras & Cláudia Guimas Almeida, 2021 apr 28, I: Journal of Cell Science.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. Accumulation of cellular prion protein within β-amyloid oligomer plaques in aged human brains

    Reisuke H Takahashi, Mayumi Yokotsuka, Minoru Tobiume, Yuko Sato, Hideki Hasegawa, Toshitaka Nagao & Gunnar K Gouras, 2021 feb 23, I: Brain Pathology. s. e12941

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. 2020
  6. Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons

    Oxana Klementieva, Christophe Sandt, Isak Martinsson, Mustafa Kansiz, Gunnar Keppler Gouras & Ferenc Borondics, 2020 feb 7, I: Advanced Science. 9 s., 1903004.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies

    Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K. Gouras & 1 andra, Laurent Roybon, 2020, I: Stem Cell Reports. 15, 1, s. 256-273 18 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. Hyperinflammation and Fibrosis in Severe COVID-19 Patients: Galectin-3, a Target Molecule to Consider

    Juan Garcia-Revilla, Tomas Deierborg, Jose Luis Venero & Antonio Boza-Serrano, 2020, I: Frontiers in Immunology. 11, 2069.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. 2019
  10. Aging, metabolism, synaptic activity, and Aβ in Alzheimer's disease

    Gunnar K. Gouras, 2019 jan 1, I: Frontiers in Aging Neuroscience. 10, JUL, 185.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  11. APP depletion alters selective pre- and post-synaptic proteins

    Isak Martinsson, Estibaliz Capetillo-Zarate, Mathilde Faideau, Katarina Willén, Noemi Esteras, Susanne Frykman, Lars O. Tjernberg & Gunnar K. Gouras, 2019, I: Molecular and Cellular Neuroscience. 95, s. 86-95 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. On the Nature of β-Amyloid at Synapses

    Isak Martinsson, 2019, Lund: Lund University: Faculty of Medicine. 83 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  13. Poly(propylene imine) dendrimers with histidine-maltose shell as novel type of nanoparticles for synapse and memory protection.

    Ester Aso, Isak Martinsson, Dietmar Appelhans, C Effenberg, Núria Benseny-Cases, Gunnar Gouras, Isidre Ferrer & Oxana Klementieva, 2019, I: Nanomedicine: Nanotechnology, Biology, and Medicine. s. 198-209

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. 2018
  15. Nano-scale Infrared Imaging of β-sheet Structures in Synaptic Junctions of Primary Neurons Isolated from Transgenic Mice

    O. Klementieva, J. Mathurin, A. Engdahl, R. Freitas, K. Willen, P. Uvdal, L. M. Miller & G. Gouras, 2018 okt 29, 2018 43rd International Conference on Infrared Millimeter and Terahertz Waves, IRMMW-THz 2018. IEEE Computer Society, Vol. 2018-September. 8510376

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

  16. Prion-like seeding and nucleation of intracellular amyloid-β

    Tomas T. Olsson, Oxana Klementieva & Gunnar K. Gouras, 2018 maj 1, I: Neurobiology of Disease. 113, s. 1-10 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease

    Chao Wang, Igor A. Iashchishyn, Jonathan Pansieri, Sofie Nyström, Oxana Klementieva, John Kara, Istvan Horvath, Roman Moskalenko, Reza Rofougaran, Gunnar Gouras, Gabor G. Kovacs, S. K. Shankar & Ludmilla A. Morozova-Roche, 2018, I: Scientific Reports. 8, 1, 12836.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. 2017
  19. 3D membrane segmentation and quantification of intact thick cells using cryo soft X-ray transmission microscopy: A pilot study

    Rubén Cárdenes, Chong Zhang, Oxana Klementieva, Stephan Werner, Peter Guttmann, Christoph Pratsch, Josep Cladera & Bart H. Bijnens, 2017 apr 1, I: PLoS ONE. 12, 4, e0174324.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Plaque formation and the intraneuronal accumulation of β-amyloid in Alzheimer's disease

    Reisuke H. Takahashi, Toshitaka Nagao & Gunnar K. Gouras, 2017 apr 1, I: Pathology International. 67, 4, s. 185-193 9 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  21. Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP

    O. Klementieva, K. Willén, I. Martinsson, B. Israelsson, A. Engdahl, J. Cladera, P. Uvdal & G. K. Gouras, 2017 mar 13, I: Nature Communications. 8, 14726.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A

    Katarina Willén, James R Edgar, Takafumi Hasegawa, Nobuyuki Tanaka, Clare E Futter & Gunnar K Gouras, 2017, I: Molecular Neurodegeneration. 12, 61.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. Heterogeneous Association of Alzheimer's Disease-Linked Amyloid-β and Amyloid-β Protein Precursor with Synapses

    Katarina Willén, Agnieszka Sroka, Reisuke H. Takahashi & Gunnar K. Gouras, 2017, I: Journal of Alzheimer's Disease. 60, 2, s. 511-524 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. Involvement of endosomal and synaptic Aβ in models of Alzheimer's disease.

    Katarina Willén, 2017, Lund: Lund University: Faculty of Medicine. 80 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  25. 2016
  26. The endocytic pathway in microglia during health, aging and Alzheimer's disease

    Santiago Solé-Domènech, Dana L. Cruz, Estibaliz Capetillo-Zarate & Frederick R. Maxfield, 2016 dec 1, I: Ageing Research Reviews. 32, s. 89-103 15 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  27. Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease

    Brenna C. Beckelman, Stephen Day, Xueyan Zhou, Maggie Donohue, Gunnar K. Gouras, Eric Klann, C. Dirk Keene & Tao Ma, 2016 sep 6, I: Journal of Alzheimer's Disease. 54, 2, s. 669-678 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. Brain activity and Alzheimer's disease: A complex relationship

    Oskar Hansson & Gunnar Gouras, 2016 aug 1, I: Brain. 139, 8, s. 2109-2110 2 s.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  29. Direct High Affinity Interaction between Aβ42 and GSK3α Stimulates Hyperphosphorylation of Tau. A New Molecular Link in Alzheimer's Disease?

    Christopher Dunning, Gavin McGauran, Katarina Willén, Gunnar Gouras, David J O'Connell & Sara Linse, 2016, I: ACS Chemical Neuroscience. 7, 2, s. 161-170

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. 2015
  31. A cell culture model for monitoring α-synuclein cell-to-cell transfer.

    Juan F Reyes, Tomas Olsson, Jennifer T Lamberts, Michael J Devine, Tilo Kunath & Patrik Brundin, 2015, I: Neurobiology of Disease. 77, Jul 16, s. 266-275

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. ADAM10 and BACE1 are localized to synaptic vesicles.

    Jolanta L Lundgren, Saheeb Ahmed, Sophia Schedin-Weiss, Gunnar Gouras, Bengt Winblad, Lars O Tjernberg & Susanne Frykman, 2015, I: Journal of Neurochemistry. 135, 3, s. 606-615

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular beta amyloid accumulation.

    James R Edgar, Katarina Willén, Gunnar K Gouras & Clare E Futter, 2015, I: Journal of Cell Science. 128, 14, s. 2520-2528

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. β-amyloid Peptides and Amyloid Plaques in Alzheimer's Disease.

    Gunnar Gouras, Tomas Olsson & Oskar Hansson, 2015, I: Neurotherapeutics. 12, 1, s. 3-11

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  35. 2014
  36. Detection of pre-plaque amyloid aggregation using FTIR

    Oxana Klementieva, Anders Engdahl, Mathilde Faideau, Katarina Willén, Per Uvdal & Gunnar Keppler Gouras, 2014 jul 1, I: Alzheimer's and Dementia. 10, 4

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. Activity-independent release of the amyloid β-peptide from rat brain nerve terminals.

    Jolanta L Lundgren, Saheeb Ahmed, Bengt Winblad, Gunnar Gouras, Lars O Tjernberg & Susanne Frykman, 2014, I: Neuroscience Letters. 566, Mar 3, s. 125-130

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. Glutamine Synthetase Stability and Subcellular Distribution in Astrocytes are Regulated by G-Aminobutyric Type B Receptors.

    Deborah Huyghe, Yasuko Nakamura, Miho Terunuma, Mathilde Faideau, Philip Haydon, N Mene Pangalos & Moss J Stephen, 2014, I: Journal of Biological Chemistry. 289, 42, s. 28808-28815

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  39. Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.

    Sonia George, Annica Rönnbäck, Gunnar Gouras, Géraldine Petit, Fiona Grueninger, Bengt Winblad, Caroline Graff & Patrik Brundin, 2014, I: Acta Neuropathologica Communications. 2, 1, 17.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  40. The Inside-Out Amyloid Hypothesis and Synapse Pathology in Alzheimer's Disease.

    Gunnar Gouras, Katarina Willén & Mathilde Faideau, 2014, I: Neurodegenerative Diseases. 13, 2-3, s. 142-146

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. 2013
  42. Accumulation of Intraneuronal beta-Amyloid 42 Peptides Is Associated with Early Changes in Microtubule-Associated Protein 2 in Neurites and Synapses

    Reisuke H. Takahashi, Estibaliz Capetillo-Zarate, Michael T. Lin, Teresa A. Milner & Gunnar Gouras, 2013, I: PLoS ONE. 8, 1

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. mTOR: at the crossroads of aging, chaperones, and Alzheimer's disease.

    Gunnar Gouras, 2013, I: Journal of Neurochemistry. 124, 6, s. 747-748

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  44. 2012
  45. Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice

    Magali Dumont, Cliona Stack, Ceyhan Elipenahli, Shari Jainuddin, Meri Gerges, Natalia Starkova, Noel Y. Calingasan, Lichuan Yang, Davide Tampellini, Anatoly A. Starkov, Robin B. Chan, Gilbert Di Paolo, Aurora Pujol & M. Flint Beal, 2012, I: Human Molecular Genetics. 21, 23, s. 5091-5105

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. Critical role of intraneuronal A beta in Alzheimer's disease: Technical challenges in studying intracellular A beta

    Gunnar Gouras, Katarina Willén & Davide Tampellini, 2012, I: Life Sciences. 91, 23-24, s. 1153-1158

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. Intraneuronal A beta Accumulation, Amyloid Plaques, and Synapse Pathology in Alzheimer's Disease

    Estibaliz Capetillo-Zarate, Luis Gracia, Davide Tampellini & Gunnar Gouras, 2012, I: Neurodegenerative Diseases. 10, 1-4, s. 56-59

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. Pathology of Synapses and Dendritic Spines

    Shira Knafo, Gunnar Gouras, Xiao-Xin Yan & Tara Spires-Jones, 2012, I: Journal of Neural Transplantation & Plasticity. 972432.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  49. 2011
  50. Analysis of vesicular trafficking in primary neurons by live imaging.

    Davide Tampellini & Gunnar Gouras, 2011, I: Methods in Molecular Biology. 793, s. 343-350

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. High-Resolution 3D Reconstruction Reveals Intra-Synaptic Amyloid Fibrils

    Estibaliz Capetillo-Zarate, Luis Gracia, Fangmin Yu, Jason R. Banfelder, Michael T. Lin, Davide Tampellini & Gunnar Gouras, 2011, I: American Journal of Pathology. 179, 5, s. 2551-2558

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. Impaired β-Amyloid Secretion in Alzheimer's Disease Pathogenesis.

    Davide Tampellini, Nawreen Rahman, Michael Linell, Estibaliz Capetillo-Zarate & Gunnar Gouras, 2011, I: The Journal of neuroscience. 31, 43, s. 15384-15390

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  53. 1990
  54. Lack of glutathione transferase activity in intermittent claudication

    H Pessah-Rasmussen, L. Stavenow, J Seidegard, J O Solem & B Israelsson, 1990 apr 1, I: International Angiology. 9, 2, s. 70-4

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift