Proteinbioinformatik

Organisation: forskargrupp

Fler filtreringsmöjligheter
  1. 2019
  2. Benchmarking subcellular localization and variant tolerance predictors on membrane proteins

    Orioli, T. & Mauno Vihinen, 2019 jul 16, I : BMC Genomics. 20, 8, 547.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

    Ekaterina Savchenko, Teku, G. N., Antonio Boza-Serrano, Kaspar Russ, Berns, M., Tomas Deierborg, Lamas, N. J., Wichterle, H., Rothstein, J., Henderson, C. E., Mauno Vihinen & Laurent Roybon, 2019 jul 3, I : Scientific Reports. 9, 1, 9610.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. How good are pathogenicity predictors in detecting benign variants?

    Abhishek Niroula & Mauno Vihinen, 2019 feb 11, I : PLoS Computational Biology. 15, 2, e1006481.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. Checklist for gene/disease-specific variation database curators to enable ethical data management

    Ekong, R. & Mauno Vihinen, 2019, I : Human Mutation.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. 2018
  7. Systematics for types and effects of DNA variations

    Mauno Vihinen, 2018 dec 28, I : BMC Genomics. 19, 1, 974.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  8. Pan-cancer analysis of neoepitopes

    Teku, G. N. & Mauno Vihinen, 2018 dec 1, I : Scientific Reports. 8, 1, 12735.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Representativeness of variation benchmark datasets

    Gerard C P Schaafsma & Mauno Vihinen, 2018 nov 29, I : BMC Bioinformatics. 19, 1, s. 461

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. Simulation of the dynamics of primary immunodeficiencies in B cells

    Teku, G. N. & Mauno Vihinen, 2018 aug 2, I : Frontiers in Immunology. 9, AUG, 1785.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering

    Rasila, T. S., Pulkkinen, E., Kiljunen, S., Haapa-Paananen, S., Pajunen, M. I., Salminen, A., Paulin, L., Mauno Vihinen, Rice, P. A. & Savilahti, H., 2018 maj 18, I : Nucleic Acids Research. 46, 9, s. 4649-4661 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Pon-tstab: Protein variant stability predictor. importance of training data quality

    Yang, Y., Urolagin, S., Abhishek Niroula, Ding, X., Shen, B. & Mauno Vihinen, 2018 apr 1, I : International Journal of Molecular Sciences. 19, 4, 1009.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. NDDVD: an integrated and manually curated Neurodegenerative Diseases Variation Database

    Yang, Y., Xu, C., Liu, X., Xu, C., Zhang, Y., Shen, L., Mauno Vihinen & Shen, B., 2018 jan 1, I : Database : the journal of biological databases and curation. 2018, bay018.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. 2017
  15. Targeting Neuroinflammation to Treat Alzheimer’s Disease

    Ardura-Fabregat, A., Boddeke, E. W. G. M., Boza-Serrano, A., Brioschi, S., Castro-Gomez, S., Ceyzériat, K., Dansokho, C., Dierkes, T., Gelders, G., Heneka, M. T., Hoeijmakers, L., Hoffmann, A., Iaccarino, L., Jahnert, S., Kuhbandner, K., Landreth, G., Lonnemann, N., Löschmann, P. A., McManus, R. M., Paulus, A. & 11 andraReemst, K., Sanchez-Caro, J. M., Tiberi, A., van der Perren, A., Vautheny, A., Venegas, C., Webers, A., Weydt, P., Wijasa, T. S., Xiang, X. & Yang, Y., 2017 dec 19, I : CNS Drugs. 31, 12, s. 1-26 26 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  16. PON-SC - program for identifying steric clashes caused by amino acid substitutions

    Čalyševa, J. & Mauno Vihinen, 2017 nov 29, I : BMC Bioinformatics. 18, 1, 531.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. Direct evidence for a polygenic etiology in familial multiple myeloma

    Halvarsson, B-M., Wihlborg, A-K., Ali, M., Lemonakis, K., Johnsson, E., Niroula, A., Cibulskis, C., Weinhold, N., Försti, A., Alici, E., Langer, C., Pfreundschuh, M., Goldschmidt, H., Mellqvist, U-H., Turesson, I., Waage, A., Hemminki, K., Golub, T., Nahi, H., Gullberg, U. & 2 andraMarkus Hansson & Björn Nilsson, 2017 apr 11, I : Blood Advances. 1, 10, s. 619-623

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. How to Define Pathogenicity, Health, and Disease?

    Mauno Vihinen, 2017 feb 1, I : Human Mutation. 38, 2, s. 129-136 8 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Expanded national database collection and data coverage in the FINDbase worldwide database for clinically relevant genomic variation allele frequencies

    Viennas, E., Komianou, A., Mizzi, C., Stojiljkovic, M., Mitropoulou, C., Muilu, J., Mauno Vihinen, Grypioti, P., Papadaki, S., Pavlidis, C., Zukic, B., Katsila, T., Van Der Spek, P. J., Pavlovic, S., Tzimas, G. & Patrinos, G. P., 2017 jan 1, I : Nucleic Acids Research. 45, D1, s. D846-D853

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Computational analysis on the effects of variations in T and B cells. Primary immunodeficiencies and cancer neoepitopes

    Teku, G. N., 2017, Lund: Lund University, Faculty of Medicine. 74 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  21. One Gene, Several Diseases: The Characteristics of Pleiotropic Proteins

    Mauno Vihinen, 2017, I : Human Mutation. 38, 3, s. 241-241 1 s.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  22. Performance of in silico tools for the evaluation of p16INK4a (CDKN2A) variants in CAGI

    Carraro, M., Minervini, G., Giollo, M., Bromberg, Y., Capriotti, E., Casadio, R., Dunbrack, R., Elefanti, L., Fariselli, P., Ferrari, C., Gough, J., Katsonis, P., Leonardi, E., Lichtarge, O., Menin, C., Martelli, P. L., Niroula, A., Pal, L. R., Repo, S., Scaini, M. C. & 11 andraMauno Vihinen, Wei, Q., Xu, Q., Yang, Y., Yin, Y., Zaucha, J., Zhao, H., Zhou, Y., Brenner, S. E., Moult, J. & Tosatto, S. C. E., 2017, I : Human Mutation. 38, 9, s. 1042-1050

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. PON-P and PON-P2 predictor performance in CAGI challenges: Lessons learned

    Abhishek Niroula & Mauno Vihinen, 2017, I : Human Mutation. 38, 9, s. 1085-1091

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. Tools and annotations for variation

    Gerard C.P. Schaafsma, 2017, Lund: Lund University, Faculty of Medicine. 58 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  25. Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges

    Daneshjou, R., Wang, Y., Bromberg, Y., Bovo, S., Martelli, P. L., Babbi, G., Lena, P. D., Casadio, R., Edwards, M., Gifford, D., Jones, D. T. W., Sundaram, L., Bhat, R., Li, X., Pal, L. R., Kundu, K., Yin, Y., Moult, J., Jiang, Y., Pejaver, V. R. & 31 andraPagel, K. A., Li, B., Mooney, S. D., Radivojac, P., Shah, S., Carraro, M., Gasparini, A., Leonardi, E., Giollo, M., Ferrari, C., Tosatto, S. C. E., Bachar, E., Azaria, J. R., Ofran, Y., Unger, R., Abhishek Niroula, Mauno Vihinen, Chang, B., Wang, M. H., Franke, A., Petersen, B. S., Pirooznia, M., Zandi, P., Mccombie, R., Potash, J. B., Altman, R. B., Klein, T. E., Hoskins, R. A., Repo, S., Brenner, S. E. & Morgan, A. A., 2017, I : Human Mutation. 38, 9, s. 1182-1192

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. 2016
  27. Establishment of an international database for genetic variants in esophageal cancer

    Mauno Vihinen, 2016 okt 1, I : Annals of the New York Academy of Sciences. 1381, 1, s. 45-49 5 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. PON-Sol: Prediction of effects of amino acid substitutions on protein solubility

    Yang, Y., Abhishek Niroula, Shen, B. & Mauno Vihinen, 2016 jul 1, I : Bioinformatics. 32, 13, s. 2032-2034

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. Variation Interpretation Predictors: Principles, Types, Performance, and Choice

    Abhishek Niroula & Mauno Vihinen, 2016 jun 1, I : Human Mutation. 37, 6, s. 579-597 19 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. PON-mt-tRNA: a multifactorial probability-based method for classification of mitochondrial tRNA variations.

    Abhishek Niroula & Mauno Vihinen, 2016, I : Nucleic Acids Research. 44, 5, s. 2020-2027

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. Tools and pipelines for interpreting the impacts of genetic variants

    Abhishek Niroula, 2016, Lund: Lund University, Faculty of Medicine. 71 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  32. VariOtator, A Software Tool for Variation Annotation with the Variation Ontology.

    Gerard Schaafsma & Mauno Vihinen, 2016, I : Human Mutation. 37, 4, s. 344-349

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. 2015
  34. Characterization of All Possible Single-Nucleotide Change Caused Amino Acid Substitutions in the Kinase Domain of Bruton Tyrosine Kinase

    Valiaho, J., Faisal, I., Ortutay, C., Smith, C. I. E. & Mauno Vihinen, 2015, I : Human Mutation. 36, 6, s. 638-647

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Classification of Amino Acid Substitutions in Mismatch Repair Proteins Using PON-MMR2.

    Abhishek Niroula & Mauno Vihinen, 2015, I : Human Mutation. 36, 12, s. 1128-1134

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. Finding Our Way through Phenotypes.

    Deans, A. R., Lewis, S. E., Huala, E., Anzaldo, S. S., Ashburner, M., Balhoff, J. P., Blackburn, D. C., Blake, J. A., Burleigh, J. G., Chanet, B., Cooper, L. D., Courtot, M., Csösz, S., Cui, H., Dahdul, W., Das, S., Dececchi, T. A., Dettai, A., Diogo, R., Druzinsky, R. E. & 54 andraDumontier, M., Franz, N. M., Friedrich, F., Gkoutos, G. V., Haendel, M., Harmon, L. J., Hayamizu, T. F., He, Y., Hines, H. M., Ibrahim, N., Jackson, L. M., Jaiswal, P., James-Zorn, C., Köhler, S., Lecointre, G., Lapp, H., Lawrence, C. J., Le Novère, N., Lundberg, J. G., Macklin, J., Mast, A. R., Midford, P. E., Mikó, I., Mungall, C. J., Oellrich, A., Osumi-Sutherland, D., Parkinson, H., Ramírez, M. J., Richter, S., Robinson, P. N., Ruttenberg, A., Schulz, K. S., Segerdell, E., Seltmann, K. C., Sharkey, M. J., Smith, A. D., Smith, B., Specht, C. D., Squires, R. B., Thacker, R. W., Thessen, A., Fernandez-Triana, J., Mauno Vihinen, Vize, P. D., Vogt, L., Wall, C. E., Walls, R. L., Westerfeld, M., Wharton, R. A., Wirkner, C. S., Woolley, J. B., Yoder, M. J., Zorn, A. M. & Mabee, P., 2015, I : PLoS Biology. 13, 1, e1002033.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. Genetic Variation in Bruton Tyrosine Kinase

    Gerard C. P. Schaafsma & Mauno Vihinen, 2015, Agammaglobulinemia. Plebani, A. & Lougaris, V. (red.). Cham: Springer, s. 75-85 11 s.

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  38. Harmful somatic amino acid substitutions affect key pathways in cancers.

    Abhishek Niroula & Mauno Vihinen, 2015, I : BMC Medical Genomics. 8, 1, 53.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  39. Muddled genetic terms miss and mess the message.

    Mauno Vihinen, 2015, I : Trends in Genetics. 31, 8, s. 423-425

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  40. No more hidden solutions in bioinformatics.

    Mauno Vihinen, 2015, I : Nature. 521, 7552, s. 261-261

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  41. PON-P2: Prediction Method for Fast and Reliable Identification of Harmful Variants.

    Abhishek Niroula, Urolagin, S. & Mauno Vihinen, 2015, I : PLoS ONE. 10, 2, e0117380.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. Specific autoantibody profiles and disease subgroups correlate with circulating micro-RNA in systemic sclerosis.

    Dirk Wuttge, Carlsen, A. L., Teku, G., Steen, S. O., Marie Wildt, Mauno Vihinen, Roger Hesselstrand & Heegaard, N. H. H., 2015, I : Rheumatology. 54, 11, s. 2100-2107

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Standard development at the Human Variome Project.

    Smith, T. D. & Mauno Vihinen, 2015, I : Database: the Journal of Biological Databases and Curation. 2015, s. bav024

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. The importance of proper testing of predictor performance.

    Mauno Vihinen, 2015, I : Human Mutation. 36, 5, s. iii-iiv

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  45. Types and effects of protein variations.

    Mauno Vihinen, 2015, I : Human Genetics. 134, 4, s. 405-421

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. Varisnp, A Benchmark Database For Variations from dbSNP.

    Gerard Schaafsma & Mauno Vihinen, 2015, I : Human Mutation. 36, 2, s. 161-166

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. 2014
  48. Clustering of gene ontology terms in genomes.

    Tiirikka, T., Siermala, M. & Mauno Vihinen, 2014, I : Gene. 550, 2, s. 155-164

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. Contribution of pseudogenes to sequence diversity.

    Mauno Vihinen, 2014, Pseudogenes. Functions and Protocols.. Poliseno, L. (red.). Springer, s. 15-24

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  50. Identification of core T cell network based on immunome interactome.

    Teku, G., Ortutay, C. & Mauno Vihinen, 2014, I : BMC Systems Biology. 8, 1, 17.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. Majority Vote and Other Problems when using Computational Tools.

    Mauno Vihinen, 2014, I : Human Mutation. 35, 8, s. 912-914

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. Novel Association of Neurofibromatosis Type 1-Causing Mutations in Families With Neurofibromatosis-Noonan Syndrome

    Ekvall, S., Sjors, K., Jonzon, A., Mauno Vihinen, Anneren, G. & Bondeson, M-L., 2014, I : American Journal of Medical Genetics. Part A. 164, 3, s. 579-587

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  53. Performance of Protein Disorder Prediction Programs on Amino Acid Substitutions

    Ali, H., Urolagin, S., Gurarslan, O. & Mauno Vihinen, 2014, I : Human Mutation. 35, 7, s. 794-804

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  54. Proper reporting of predictor performance.

    Mauno Vihinen, 2014, I : Nature Methods. 11, 8, s. 781-781

    Forskningsoutput: TidskriftsbidragLetter

  55. Variation ontology: annotator guide.

    Mauno Vihinen, 2014, I : Journal of Biomedical Semantics. 5, 1, 9.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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