Stamceller till röda blodkroppar

Organisation: forskargrupp

Fler filtreringsmöjligheter
  1. 2021
  2. Bone marrow transplantation without myeloablative conditioning in a mouse model for Diamond-Blackfan anemia corrects the disease phenotype

    Maria Dahl, Sarah Warsi, Yang Liu, Shubhranshu Debnath, Matilda Billing, Kavitha Siva, Johan Flygare & Stefan Karlsson, 2021, I: Experimental Hematology. 99, s. 44-53.e2

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. The active component of ginseng, ginsenoside Rb1, improves erythropoiesis in models of Diamond–Blackfan anemia by targeting Nemo-like kinase

    Mark C. Wilkes, Kevin Jung, Britney E. Lee, Mallika Saxena, Ryan S. Sathianathen, Jacqueline D. Mercado, Cristina Perez, Johan Flygare, Anupama Narla, Bertil Glader & Kathleen M. Sakamoto, 2021, I: Journal of Biological Chemistry. 297, 3, 100988.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. 2020
  5. Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171

    Agatheeswaran Subramaniam, Kristijonas Zemaitis, Mehrnaz Safaee Talkhoncheh, David Yudovich, Alexandra Bäckström, Shubhranshu Debnath, Jun Chen, Mayur Vilas Jain, Roman Galeev, Massimiliano Gaetani, Roman A Zubarev & Jonas Larsson, 2020 nov 5, I: Blood. 136, 19, s. 2151-2161 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a

    Mark C. Wilkes, Kavitha Siva, Gianluca Varetti, Jacqueline Mercado, Ethan P. Wentworth, Cristina A. Perez, Mallika Saxena, Sharon Kam, Simryn Kapur, Jun Chen, Anu Narla, Bert Glader, Shou Lin, Manuel Serrano, Johan Flygare & Kathleen M. Sakamoto, 2020 nov 1, I: Experimental Hematology. 91, s. 65-77 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency

    Taha Sen, Mayur Jain, Magnus Gram, Alexander Mattebo, Shamit Soneji, Carl R. Walkley & Sofie Singbrant, 2020 aug 1, I: Experimental Hematology. 88, s. 28-41 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. S100A6 is a critical regulator of hematopoietic stem cells.

    Hooi Min Tan Grahn, Abhishek Niroula, Akos Vegvari, Leal Oburoglu, Maroulio Pertesi, Sarah Warsi, Fatemeh Safi, Natsumi Miharada, Sandra C. Garcia, Kavitha Siva, Yang Liu, Emma Rörby, Björn Nilsson, Roman A. Zubarev & Stefan Karlsson, 2020 jun 19, I: Leukemia.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

    Alison M. Taylor, Elizabeth R. Macari, Iris T. Chan, Megan C. Blair, Sergei Doulatov, Linda T. Vo, David M. Raiser, Kavitha Siva, Anindita Basak, Mehdi Pirouz, Arish N. Shah, Katherine McGrath, Jessica M. Humphries, Emma Stillman, Blanche P. Alter, Eliezer Calo, Richard I. Gregory, Vijay G. Sankaran, Johan Flygare, Benjamin L. Ebert & 3 andra, Yi Zhou, George Q. Daley & Leonard I. Zon, 2020, I: Science Translational Medicine. 12, 566, eabb5831.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase

    M. C. Wilkes, K. Siva, J. Chen, G. Varetti, M. Y. Youn, H. Chae, F. Ek, R. Olsson, T. Lundbäck, D. P. Dever, T. Nishimura, A. Narla, B. Glader, H. Nakauchi, M. H. Porteus, C. E. Repellin, H. T. Gazda, S. Lin, M. Serrano, J. Flygare & 1 andra, K. M. Sakamoto, 2020, I: Nature Communications. 11, 1, 3344.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. 2019
  12. Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells

    Zahra Masoumi, Gregory E. Maes, Koen Herten, Álvaro Cortés-Calabuig, Abdul Ghani Alattar, Eva Hanson, Lena Erlandsson, Eva Mezey, Mattias Magnusson, Joris R. Vermeesch, Mary Familari & Stefan R. Hansson, 2019 apr 25, I: International Journal of Molecular Sciences. 20, 8, 2038.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia

    Kavitha Siva, Fredrik Ek, Jun Chen, Abdul Ghani Alattar, Kristmundur Sigmundsson, Roger Olsson, Marcin Wlodarski, Thomas Lundbäck & Johan Flygare, 2019, I: SLAS Discovery. 24, 3, s. 304-313 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing

    Mehdi Amirhosseini, Magnus Bernhardsson, Pernilla Lång, Göran Andersson, Johan Flygare & Anna Fahlgren, 2019, I: Journal of Cellular Physiology. 234, 9, s. 16503-16516 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. 2018
  16. Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors

    Melissa Ilsley, Sandra Capellera-Garcia, Kishori Dhulipala, Alban Johansson & Johan Flygare, 2018 dec 14, I: Journal of visualized experiments : JoVE. 142, e58464.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. On new and current treatments for Diamond-Blackfan anemia

    Sara Sjögren, 2018, Lund: Lund University: Faculty of Medicine. 80 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  18. Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development

    Sandra Capellera Garcia, 2018, Lund: Lund University: Faculty of Medicine. 111 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  19. 2017
  20. Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

    Karolina Komorowska, Alexander Doyle, Martin Wahlestedt, Agatheeswaran Subramaniam, Shubhranshu Debnath, Jun Chen, Shamit Soneji, Ben Van Handel, Hanna K.A. Mikkola, Kenichi Miharada, David Bryder, Jonas Larsson & Mattias Magnusson, 2017 dec 19, I: Cell Reports. 21, 12, s. 3514-3523 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Direct lineage reprogramming: a useful addition to the blood cell research toolbox

    Sandra Capellera-Garcia & Johan Flygare, 2017 feb 1, I: Expert Review of Hematology. 10, 2, s. 107-109

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  22. 2016
  23. Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

    Julian Pulecio, Oriol Alejo-Valle, Sandra Capellera-Garcia, Marianna Vitaloni, Paula Rio, Eva Mejía-Ramírez, Ilaria Caserta, Juan A Bueren, Johan Flygare & Angel Raya, 2016 okt 11, I: Cell Reports. 17, 3, s. 671-683 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion

    Sandra Capellera-Garcia, Julian Pulecio, Kishori Dhulipala, Kavitha Siva, Violeta Rayon-Estrada, Sofie Singbrant, Mikael N E Sommarin, Carl R Walkley, Shamit Soneji, Göran Karlsson, Ángel Raya, Vijay G Sankaran & Johan Flygare, 2016 jun 14, I: Cell Reports. 15, 11, s. 2550-2562 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. 2015
  26. Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

    Sara Sjögren, Kavitha Siva, Shamit Soneji, Amee J George, Marcus Winkler, Pekka Jaako, Marcin Wlodarski, Stefan Karlsson, Ross D Hannan & Johan Flygare, 2015, I: British Journal of Haematology. 171, 4, s. 517-529

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. 2012
  28. Progress towards Mechanism-Based Treatment for Diamond-Blackfan Anemia.

    Sara Sjögren & Johan Flygare, 2012, I: Scientific World Journal. 2012, 184362.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift