Undersökning av molekylära sjukdomsmekanismer vid blodcancer

1. 1998

2. Constitutive expression of the Wilms' tumor gene (WT1) in the leukemic cell line U937 blocks parts of the differentiation program

   Helena Svedberg, Kristina Chylicki, Bo Baldetorp, F J 3rd Rauscher & Urban Gullberg, 1998, I : Oncogene. 16, 7, s. 925-932

   Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

3. 2001

4. Forced expression of the Wilms tumor 1 (WT1) gene inhibits proliferation of human hematopoietic CD34(+) progenitor cells

   Helena Svedberg, Johan Richter & Urban Gullberg, 2001, I : Leukemia. 15, 12, s. 1914-1922

   Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

5. 2007

6. Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells

   Emelie Svensson, Karina Vidovic, Carin Lassen, Johan Richter, Tor Olofsson, Thoas Fioretos & Urban Gullberg, 2007, I : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 21, 12, s. 2485-2494

   Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

7. 2008

8. Gene expression analysis of BCR/ABL1-dependent transcriptional response reveals enrichment for genes involved in negative feedback regulation.

   Petra Håkansson, Björn Nilsson, Anna Andersson, Carin Lassen, Urban Gullberg & Thoas Fioretos, 2008, I : Genes, Chromosomes and Cancer. 47, 4, s. 267-275 9 s.

   Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

9. 2010

10. Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.

    Karina Vidovic, Emelie Svensson, Björn Nilsson, Britt Thuresson, Tor Olofsson, Andreas Lennartsson & Urban Gullberg, 2010, I : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 24, 5, s. 992-1000

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

11. The leukemia associated ETO nuclear repressor gene is regulated by the GATA-1 transcription factor in erythroid/megakaryocytic cells

    Ram Ajore, Rakesh Singh Dhanda, Urban Gullberg & Inge Olsson, 2010 maj 20, I : BMC Molecular Biology. 11, 38.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

12. 2013
13. Leukemia associated mutant Wilms' tumor gene 1 protein promotes expansion of human hematopoietic progenitor cells.

    Karina Vidovic, Tove Ullmark, Bodil Rosberg, Andreas Lennartsson, Tor Olofsson, Björn Nilsson & Urban Gullberg, 2013, I : Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis. 37, 10, s. 1341-1349

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

14. Role of WT1-ZNF224 interaction in the expression of the tumor suppressor interferon regulatory factor 8 in leukemia cells

    Giorgia Montano, Karina Vidovic, Chiara Palladino, Elena Cesaro, Paola Costanzo & Urban Gullberg, 2013 jul 1.

    Forskningsoutput: Konferensbidrag › Konferensabstract

15. 2014
16. The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.

    Carl Sandén, Linnea Järvstråt, Andreas Lennartsson, Per Ludvik Brattaas, Björn Nilsson & Urban Gullberg, 2014, I : Molecular Cancer. 13, 215.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

17. 2015
18. The DEK oncoprotein and its emerging roles in gene regulation.

    Carl Sandén & Urban Gullberg, 2015, I : Leukemia. 29, 8, s. 1632-1636

    Forskningsoutput: Tidskriftsbidrag › Översiktsartikel

19. WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

    Giorgia Montano, Karina Vidovic, Chiara Palladino, Elena Cesaro, Gaetano Sodaro, Concetta Quintarelli, Biagio De Angelis, Santa Errichiello, Fabrizio Pane, Paola Izzo, Michela Grosso, Urban Gullberg & Paola Costanzo, 2015, I : Oncotarget. 29, 6, s. 28223-37

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

20. 2016
21. The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.

    Giorgia Montano, Tove Ullmark, Helena Jernmark Nilsson, Gaetano Sodaro, Kristina Drott, Paola Costanzo, Karina Vidovic & Urban Gullberg, 2016, I : Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis. 40, 1, s. 60-67

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

22. 2017
23. Distinct global binding patterns of the Wilms' tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells

    Tove Ullmark, Linnea Järvstråt, Carl Sanden, Giorgia Montano, Helena Jernmark-Nilsson, Henrik Lilljebjörn, Andreas Lennartsson, Thoas Fioretos, Kristina Drott, Karina Vidovic, Björn Nilsson & Urban Gullberg, 2017, I : Haematologica. 102, 2, s. 336-345

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

24. The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo

    Annarita Scialdone, Muhammad Sharif Hasni, Jesper Kofoed Damm, Andreas Lennartsson, Urban Gullberg & Kristina Drott, 2017, I : Oncotarget. 8, 23, s. 37409-37422 14 s.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

25. The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells

    Helena Jernmark Nilsson, Giorgia Montano, Tove Ullmark, Andreas Lennartsson, Kristina Drott, Linnea Järvstråt, Björn Nilsson, Karina Vidovic & Urban Gullberg, 2017, I : Oncotarget. 8, 50, s. 87136-87150

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

26. Direct evidence for a polygenic etiology in familial multiple myeloma

    Britt-Marie Halvarsson, Anna-Karin Wihlborg, Mina Ali, Konstantinos Lemonakis, Ellinor Johnsson, Abhishek Niroula, Carrie Cibulskis, Niels Weinhold, Asta Försti, Evren Alici, Christian Langer, Michael Pfreundschuh, Hartmut Goldschmidt, Ulf-Henrik Mellqvist, Ingemar Turesson, Anders Waage, Kari Hemminki, Todd Golub, Hareth Nahi, Urban Gullberg & 2 andra, Markus Hansson & Björn Nilsson, 2017 apr 11, I : Blood Advances. 1, 10, s. 619-623

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

27. 2018
28. Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma

    Molly Went, Asta Försti, Kari Hemminki, Britt-Marie Halvarsson, Mina Ali, Urban Gullberg, Ellinor Johnsson, Anna-Karin Wihlborg, Markus Hansson, Björn Nilsson, Richard S Houlston & The PRACTICAL Consortium The PRACTICAL Consortium, 2018, I : Nature Communications. 9, 1, 3707.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

29. Role of ZNF224 in c-Myc repression and imatinib responsiveness in chronic myeloid leukemia

    Gaetano Sodaro, Elena Cesaro, Giorgia Montano, Giancarlo Blasio, Federica Fiorentino, Simona Romano, Arnaud Jacquel, Patrick Aurberger & Paola Costanzo, 2018, I : Oncotarget. 9, 3, s. 3417-3431 15 s.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

30. Target Genes of WT1 in Leukemic Cells

    Helena Jernmark Nilsson, Giorgia Montano, Tove Ullmark, Karina Vidovic, Kristina Drott & Urban Gullberg, 2018.

    Forskningsoutput: Konferensbidrag › Poster

31. The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression

    Mina Ali, Ram Ajore, Anna Karin Wihlborg, Abhishek Niroula, Bhairavi Swaminathan, Ellinor Johnsson, Owen W. Stephens, Gareth Morgan, Tobias Meissner, Ingemar Turesson, Hartmut Goldschmidt, Ulf Henrik Mellqvist, Urban Gullberg, Markus Hansson, Kari Hemminki, Hareth Nahi, Anders Waage, Niels Weinhold & Björn Nilsson, 2018 dec 1, I : Nature Communications. 9, 1, 1649.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

32. 2019

33. Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies

    Annarita Scialdone, Somayeh Khazaei, Muhammad Sharif Hasni, Andreas Lennartsson, Urban Gullberg & Kristina Drott, 2019, I : Experimental Hematology. 79, s. 35-46.e1

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

34. Lin28b controls a neonatal to adult switch in B cell positive selection

    Stijn Vanhee, Hugo Åkerstrand, Trine Ahn Kristiansen, Sebak Datta, Giorgia Montano, Stefano Vergani, Stefan Lang, Jonas Ungerbäck, Alexander Doyle, Karin Olsson, Giulia Beneventi, Christina T. Jensen, Cristian Bellodi, Shamit Soneji, Mikael Sigvardsson, Elin Jaensson Gyllenbäck & Joan Yuan, 2019, I : Science Immunology. 4, 39, eaax4453.

    Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

35. Searching for WT1 target genes in leukemic cell lines

    Helena Jernmark Nilsson, 2019, Lund: Lund University: Faculty of Medicine. 76 s.

    Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)