Translationella genomiska och funktionella studier av leukemi

Organisation: forskargrupp

Fler filtreringsmöjligheter
  1. 2021
  2. Single-cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs

    Ulrich Pfisterer, Julia Bräunig, Per Brattås, Markus Heidenblad, Göran Karlsson & Thoas Fioretos, 2021 feb 21, I: Genes, Chromosomes and Cancer.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  3. Clinical and genomic characterization of patients diagnosed with the provisional entity Acute myeloid leukemia with BCR-ABL1, a Swedish population-based study

    Christina Orsmark-Pietras, Niklas Landberg, Fryderyk Lorenz, Bertil Uggla, Martin Höglund, Sören Lehmann, Åsa Derolf, Stefan Deneberg, Petar Antunovic, Jörg Cammenga, Lars Möllgård, Lovisa Wennström, Henrik Lilljebjörn, Marianne Rissler, Thoas Fioretos & Vladimir Lj Lazarevic, 2021 jan 12, I: Genes, Chromosomes and Cancer.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. 2020
  5. A dynamic mutational landscape associated with an inter-regionally diverse immune response in malignant rhabdoid tumour

    Hiroaki Yasui, Anders Valind, Jenny Karlsson, Christina Pietras, Caroline Jansson, Joakim Wille, Patrik Romerius, Torbjörn Backman & David Gisselsson, 2020 sep, I: Journal of Pathology. 252, 1, s. 22-28 7 s., e5490.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

    Minjun Yang, Setareh Safavi, Eleanor L Woodward, Nicolas Duployez, Linda Olsson-arvidsson, Jonas Ungerbäck, Mikael Sigvardsson, Marketa Zaliova, Jan Zuna, Thoas Fioretos, Bertil Johansson, Karolin H Nord & Kajsa Paulsson, 2020 aug 20, I: Blood. 136, 8, s. 946-956 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

    Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, Maria Rodriguez-Zabala, Marion Chapellier, Carl Högberg, Mia Eriksson, David Yudovich, Mansi Shah, Mats Ehinger, Björn Nilsson, Jonas Larsson, Anna Hagström-Andersson, Benjamin L. Ebert, Ravi Bhatia & Marcus Järås, 2020 maj 26, I: Cell Reports. 31, 8, 107684.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells

    Sofia von Palffy, Niklas Landberg, Carl Sandén, Dimitra Zacharaki, Mansi Shah, Naoto Nakamichi, Nils Hansen, Maria Askmyr, Henrik Lilljebjörn, Marianne Rissler, Christine Karlsson, Stefan Scheding, Johan Richter, Connie J. Eaves, Ravi Bhatia, Marcus Järås & Thoas Fioretos, 2020, I: Haematologica. 105, 8, s. 2095-2104 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Cell Surface Markers as Therapeutic Targets in Myeloid Leukemia

    Niklas Landberg, 2020, Lund: Lund University, Faculty of Medicine. 79 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  10. 2019
  11. PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

    Kazuki Okuyama, Tobias Strid, Jacob Kuruvilla, Rajesh Somasundaram, Susana Cristobal, Emma Smith, Mahadesh Prasad, Thoas Fioretos, Henrik Lilljebjörn, Shamit Soneji, Stefan Lang, Jonas Ungerbäck & Mikael Sigvardsson, 2019 aug 1, I: PLoS Genetics. 15, 8, e1008280.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

    Minjun Yang, Mattias Vesterlund, Ioannis Siavelis, Larissa H. Moura-Castro, Anders Castor, Thoas Fioretos, Rozbeh Jafari, Henrik Lilljebjörn, Duncan T. Odom, Linda Olsson, Naveen Ravi, Eleanor L. Woodward, Louise Harewood, Janne Lehtiö & Kajsa Paulsson, 2019 apr 3, I: Nature Communications. 10, 1, 1519.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. Disseqt-distribution-based modeling of sequence space time dynamics

    R. Henningsson, G. Moratorio, A. V. Bordería, M. Vignuzzi & M. Fontes, 2019, I: Virus Evolution. 5, 2, vez028.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. FLT3 N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

    Axel Hyrenius-Wittsten, Mattias Pilheden, Antoni Falqués-Costa, Mia Eriksson, Helena Sturesson, Pauline Schneider, Priscilla Wander, Cristian Garcia-Ruiz, Jian Liu, Helena Ågerstam, Anne Hultquist, Henrik Lilljebjörn, Ronald W. Stam, Marcus Järås & Anna K. Hagström-Andersson, 2019, I: Leukemia. 33, 9, s. 2310-2314

    Forskningsoutput: TidskriftsbidragLetter

  15. Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion

    Karim H Saba, Louise Cornmark, Marianne Rissler, Thoas Fioretos, Kristina Åström, Felix Haglund, Andrew E Rosenberg, Otte Brosjö & Karolin H Nord, 2019, I: Genes, Chromosomes and Cancer. 58, 10, s. 731-736

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. Recombinant dermatan sulfate is a potent activator of heparin cofactor II-dependent inhibition of thrombin

    Emil Tykesson, Marco Maccarana, Hanna Thorsson, Jian Liu, Anders Malmström, Ulf Ellervik & Gunilla Westergren-Thorsson, 2019, I: Glycobiology. 29, 6, s. 446-451

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. 2018
  18. A field guide for cancer diagnostics using cell-free DNA: From principles to practice and clinical applications

    Anna Lena Volckmar, Holger Sültmann, Anja Riediger, Thoas Fioretos, Peter Schirmacher, Volker Endris, Albrecht Stenzinger & Steffen Dietz, 2018 mar 1, I: Genes Chromosomes and Cancer. 57, 3, s. 123-139 17 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  19. CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting

    Niklas Landberg, Sofia von Palffy, Maria Askmyr, Henrik Lilljebjörn, Carl Sandén, Marianne Rissler, Satu Mustjoki, Henrik Hjorth-Hansen, Johan Richter, Helena Ågerstam, Marcus Järås & Thoas Fioretos, 2018 feb 28, I: Haematologica. 103, 3, s. 447-455

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner

    Pablo Peña, Mia Eriksson, R Ramakrishnan, M Chapellier, Carl Högberg, C Orsmark-Pietras, J Richter, Anna Andersson, T Fioretos & M Järås, 2018, I: Leukemia. 32, 3, s. 588-596

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

    Jian Feng Li, Yu Ting Dai, Henrik Lilljebjörn, Shu Hong Shen, Bo Wen Cui, Ling Bai, Yuan Fang Liu, Mao Xiang Qian, Yasuo Kubota, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki, Linda Olsson, Ah Moy Tan, Hany Ariffin, Jing Chen, Junko Takita, Takahiko Yasuda, Hiroyuki Mano, Bertil Johansson & 8 andra, Jun J. Yang, Allen Eng Juh Yeoh, Fumihiko Hayakawa, Zhu Chen, Ching Hon Pui, Thoas Fioretos, Sai Juan Chen & Jin Yan Huang, 2018, I: Proceedings of the National Academy of Sciences of the United States of America. 115, 50, s. E11711-E11720

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. 2017
  23. Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells

    Maria Askmyr, Sofia Von Palffy, Nils Hansen, Niklas Landberg, Carl Högberg, Marianne Rissler, Helena Ågerstam & Thoas Fioretos, 2017 okt 1, I: PLoS ONE. 12, 10, e0186035.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia

    Henrik Lilljebjörn & Thoas Fioretos, 2017 sep 21, I: Blood. 130, 12, s. 1395-1401

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  25. Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib

    Niklas Landberg, Arta Dreimane, Marianne Rissler, Rolf Billström & Helena Ågerstam, 2017, I: European Journal of Haematology. 99, 5, s. 442-448 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. 2016
  27. IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

    Helena Ågerstam, Nils Hansen, Sofia von Palffy, Carl Sandén, Kristian Reckzeh, Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Maria Askmyr, Carl Högberg, Marianne Rissler, Kimmo Porkka, Hans Wadenvik, Satu Mustjoki, Johan Richter, Marcus Järås & Thoas Fioretos, 2016 dec 8, I: Blood. 128, 23, s. 2683-2693

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. 2015
  29. Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

    Helena Ågerstam, Christine Karlsson, Nils Hansen, Carl Sandén, Maria Askmyr, Sofia von Palffy, Carl Högberg, Marianne Rissler, Mark Wunderlich, Gunnar Juliusson, Johan Richter, Kjell Sjöström, Ravi Bhatia, James C Mulloy, Marcus Järås & Thoas Fioretos, 2015, I: Proceedings of the National Academy of Sciences. 112, 34, s. 10786-10791

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.

    Niklas Landberg, Nils Hansen, Maria Askmyr, Helena Ågerstam, Carin Lassen, Marianne Rissler, H H Hansen, S Mustjoki, Marcus Järås, Johan Richter & Thoas Fioretos, 2015, I: Leukemia. 30, 1, s. 255-258

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. The emerging complexity of gene fusions in cancer.

    Fredrik Mertens, Bertil Johansson, Thoas Fioretos & Felix Mitelman, 2015, I: Nature Reviews. Cancer. 15, 6, s. 371-381

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  32. The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

    Kajsa Paulsson, Henrik Lilljebjörn, Andrea Biloglav, Linda Olsson, Marianne Rissler, Anders Castor, Gisela Barbany, Linda Fogelstrand, Ann Nordgren, Helene Sjögren, Thoas Fioretos & Bertil Johansson, 2015, I: Nature Genetics. 47, 6, s. 672-676

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. 2013
  34. Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.

    Maria Askmyr, Helena Ågerstam, Nils Hansen, Sandra Gordon, Alexandros Arvanitakis, Marianne Rissler, Gunnar Juliusson, Johan Richter, Marcus Järås & Thoas Fioretos, 2013, I: Blood. 121, 18, s. 3709-3713

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. 2010
  36. Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.

    Marcus Järås, Petra Johnels, Nils Hansen, Helena Ågerstam, Panagiotis Tsapogas, Marianne Rissler, Carin Lassen, Tor Olofsson, Ole Weis Bjerrum, Johan Richter & Thoas Fioretos, 2010, I: Proceedings of the National Academy of Sciences. 107, 37, s. 16280-16285

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice

    Helena Ågerstam, Marcus Järås, Anna Andersson, Petra Johnels, Nils Hansen, Carin Lassen, Marianne Rissler, David Gisselsson Nord, Tor Olofsson, Johan Richter, Xiaolong Fan, Mats Ehinger & Thoas Fioretos, 2010, I: Blood. 116, 12, s. 2103-2111

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. 2005
  39. Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.

    Anna Andersson, Tor Olofsson, David Lindgren, Björn Nilsson, Cecilia Ritz, Patrik Edén, Carin Lassen, Johan Råde, Magnus Fontes, Helena Mörse, Jesper Heldrup, Mikael Behrendtz, Felix Mitelman, Mattias Höglund, Bertil Johansson & Thoas Fioretos, 2005, I: Proceedings of the National Academy of Sciences. 102, 52, s. 19069-19074

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift