Avdelningen för molekylärmedicin och genterapi

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  1. 2019
  2. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

    Marie E. Jönsson, Ludvik Brattås, P., Gustafsson, C., Petri, R., David Yudovich, Karolina Pircs, Verschuere, S., Madsen, S., Jenny Hansson, Jonas Larsson, Månsson, R., Meissner, A. & Johan Jakobsson, 2019 jul 18, I : Nature Communications. 10, 1, 3182.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. A dual amylin and calcitonin receptor agonist inhibits pain behavior and reduces cartilage pathology in an osteoarthritis rat model

    Katri, A., Dąbrowska, A., Löfvall, H., Karsdal, M. A., Andreassen, K. V., Thudium, C. S. & Henriksen, K., 2019 jun 5, I : Osteoarthritis and Cartilage.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells

    Zahra Masoumi, Maes, G. E., Herten, K., Cortés-Calabuig, Á., Abdul Ghani Alattar, Hanson, E., Lena Erlandsson, Mezey, E., Mattias Magnusson, Vermeesch, J. R., Mary Familari & Stefan R. Hansson, 2019 apr 25, I : International Journal of Molecular Sciences. 20, 8, 2038.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells

    Kumar, P., Beck, D., Roman Galeev, Thoms, J. A. I., Mehrnaz Safaee Talkhoncheh, Ineke de Jong, Unnikrishnan, A., Aurélie Baudet, Agatheeswaran Subramaniam, Pimanda, J. E. & Jonas Larsson, 2019 feb 26, I : Blood Advances. 3, 4, s. 681-691 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

    Melissaridou, S., Wiechec, E., Magan, M., Jain, M. V., Chung, M. K., Farnebo, L. & Roberg, K., 2019 jan 14, I : Cancer Cell International. 19, 1, 16.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia

    Siva, K., Fredrik Ek, Jun Chen, Abdul Ghani Alattar, Sigmundsson, K., Roger Olsson, Wlodarski, M., Lundbäck, T. & Johan Flygare, 2019, I : SLAS discovery : advancing life sciences R & D. 24, 3, s. 304-313 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test

    Wallenius, M., Alexander Lind, Akel, O., Karlsson, E., Svensson, M., Arvidsson, E., Ramelius, A., Törn, C., Palm, L., Åke Lernmark & Helena Elding Larsson, 2019, I : Autoimmunity. 52, 4, s. 185-191 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model

    Katri, A., Dąbrowska, A., Löfvall, H., Ding, M., Karsdal, M. A., Andreassen, K. V., Thudium, C. S. & Henriksen, K., 2019, I : Arthritis Research & Therapy. 21, 1, 68.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing

    Amirhosseini, M., Bernhardsson, M., Lång, P., Andersson, G., Johan Flygare & Fahlgren, A., 2019, I : Journal of Cellular Physiology. 234, 9, s. 16503-16516 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. Ex Vivo Expansion of Human Hematopoietic Stem Cells

    Mehrnaz Safaee Talkhoncheh, 2019, Lund: Lund University, Faculty of Medicine. 100 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  12. Genome-wide mapping of bivalent histone modifications in hepatic stem/progenitor cells

    Kanayama, K., Chiba, T., Oshima, M., Kanzaki, H., Shuhei Koide, Saraya, A., Miyagi, S., Mimura, N., Kusakabe, Y., Saito, T., Ogasawara, S., Suzuki, E., Ooka, Y., Maruyama, H., Iwama, A. & Kato, N., 2019, I : Stem Cells International. 2019, 9789240.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. GPDPLQ1237—A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in vitro

    Löfvall, H., Katri, A., Dąbrowska, A., Karsdal, M. A., Luo, Y., He, Y., Manon-Jensen, T., Dziegiel, M. H., Bay-Jensen, A-C., Thudium, C. S. & Henriksen, K., 2019, I : Scientific Reports. 9, 3050.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis

    Visnja Radulovic, van der Garde, M., Shuhei Koide, Valgardur Sigurdsson, Stefan Lang, Kaneko, S. & Kenichi Miharada, 2019, I : Cell Reports. 27, 10, s. 2826-2836.e5

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. MiR-378a suppresses tenogenic differentiation and tendon repair by targeting at TGF-β2

    Yang Liu, Feng, L., Xu, J., Yang, Z., Wu, T., Zhang, J., Shi, L., Zhu, D., Zhang, J. & Li, G., 2019, I : Stem Cell Research and Therapy. 10, 1, 108.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. Protein biomarkers associated with pain mechanisms in osteoarthritis

    Thudium, C. S., Löfvall, H., Karsdal, M. A., Bay-Jensen, A. C. & Bihlet, A. R., 2019, I : Journal of Proteomics. 190, s. 55-66

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. 2018
  18. Direct Lineage Reprogramming of Adult Mouse Fibroblast to Erythroid Progenitors

    Melissa Ilsley, Sandra Capellera-Garcia, Dhulipala, K., Johansson, A. & Johan Flygare, 2018 dec 14, I : Journal of visualized experiments : JoVE. 142, e58464.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Direct reprogramming of fibroblasts into antigen-presenting dendritic cells

    Fábio F. Rosa, Cristiana F. Pires, Kurochkin, I., Alexandra G. Ferreira, Gomes, A. M., Palma, L. G., Shaiv, K., Solanas, L., Azenha, C., Papatsenko, D., Schulz, O., E Sousa, C. R. & Carlos Filipe Pereira, 2018 dec 7, I : Science immunology. 3, 30, eaau4292.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Prospective evaluation of a combination of fungal biomarkers for the diagnosis of invasive fungal disease in high-risk haematology patients

    Hammarström, H., Stjärne Aspelund, A., Bertil Christensson, Heußel, C. P., Isaksson, J., Kondori, N., Lennart Larsson, Markowicz, P., Johan Richter, Wennerås, C. & Friman, V., 2018 sep 1, I : Mycoses. 61, 9, s. 623-632 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Fetal gene therapy for neurodegenerative disease of infants

    Massaro, G., Mattar, C. N. Z., Wong, A. M. S., Sirka, E., Buckley, S. M. K., Herbert, B. R., Karlsson, S., Perocheau, D. P., Burke, D., Heales, S., Richard-Londt, A., Brandner, S., Huebecker, M., Priestman, D. A., Platt, F. M., Mills, K., Biswas, A., Cooper, J. D., Chan, J. K. Y., Cheng, S. H. & 2 andraWaddington, S. N. & Rahim, A. A., 2018 sep, I : Nature Medicine. 24, 9, s. 1317-1323

    Forskningsoutput: TidskriftsbidragLetter

  22. Tipping clonal hematopoiesis into transformation

    Stefan Karlsson, 2018 jul 19, I : New England Journal of Medicine. 379, 3, s. 295-296 2 s.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  23. Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes

    Löfvall, H., Newbould, H., Karsdal, M. A., Dziegiel, M. H., Johan Richter, Henriksen, K. & Thudium, C. S., 2018 apr 10, I : Arthritis Research and Therapy. 20, 1, 67.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. Nucleoside analogues improve short-term prognosis of HBV-related acute-on-chronic liver failure but as not an independent risk factor

    Ye, C., Jin, X., Hooi Min Tan Grahn, Zheng, Y. & Li, W., 2018 jan, I : International Journal of Clinical and Experimental Medicine. 11, 9, s. 9779-9790

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, J., Aurélie Baudet, Abelechian, S., Bonderup, K., d'Altri, T., Porse, B., Brakebusch, C., Gunnar Juliusson & Cammenga, J., 2018, I : Genesis. 56, 9, e23238.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. Cohesin in haematopoiesis and leukaemia

    Roman Galeev & Jonas Larsson, 2018, I : Current Opinion in Hematology. 25, 4, s. 259-265 7 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  27. Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming

    Gomes, A. M., Kurochkin, I., Chang, B., Daniel, M., Law, K., Satija, N., Lachmann, A., Wang, Z., Ferreira, L., Ma'ayan, A., Chen, B. K., Papatsenko, D., Lemischka, I. R., Moore, K. A. & Carlos Filipe Pereira, 2018, I : Cell Reports.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. Development of Novel Therapies, Models, and Biomarkers for Osteoclast-Related Diseases

    Löfvall, H., 2018, Lund: Lund University, Faculty of Medicine. 114 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  29. Direct role of FLT3 in regulation of early lymphoid progenitors

    Zriwil, A., Charlotta Böiers, Trine A. Kristiansen, Wittmann, L., Joan Yuan, Nerlov, C., Ewa Sitnicka & Jacobsen, S. E. W., 2018, I : British Journal of Haematology. 183, 4, s. 588-600

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. Identification of intrinsic regulators in normal and malignant human hematopoiesis. An RNA-interference approach.

    Roman Galeev, 2018, Lund: Lund University, Faculty of Medicine. 127 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  31. Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner

    Pablo Peña, Eriksson, M., R Ramakrishnan, M Chapellier, Högberg, C., C Orsmark-Pietras, J Richter, Anna Andersson, T Fioretos & M Järås, 2018, I : Leukemia. 32, 3, s. 588-596

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. In vitro tumorigenic assay: colony forming assay for cancer stem cells

    Rajendran, V. & Jain, M. V., 2018, Methods in Molecular Biology. Humana Press, Vol. 1692. s. 89-95 7 s. (Methods in Molecular Biology; vol. 1692).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  33. On new and current treatments for Diamond-Blackfan anemia

    Sara Sjögren, 2018, Lund: Lund University, Faculty of Medicine. 80 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  34. Pentaisomaltose, an Alternative to DMSO. Engraftment of Cryopreserved Human CD34+ Cells in Immunodeficient NSG Mice

    Svalgaard, J. D., Mehrnaz Safaee Talkhoncheh, Haastrup, E. K., Munthe-Fog, L., Clausen, C., Hansen, M. B., Andersen, P., Gørløv, J. S., Jonas Larsson & Fischer-Nielsen, A., 2018, I : Cell Transplantation. 27, 9, s. 1407-1412 6 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development

    Sandra Capellera Garcia, 2018, Lund: Lund University, Faculty of Medicine. 111 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  36. Regulation of unfolded protein response in hematopoietic stem cells

    Valgardur Sigurdsson & Kenichi Miharada, 2018, I : International Journal of Hematology. 107, 6, s. 627-633

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis

    Ilana Moscatelli, Löfvall, H., Schneider Thudium, C., Rothe, M., Montano, C., Kertész, Z., Sirin, M., Schulz, A., Schambach, A., Henriksen, K. & Johan Richter, 2018, I : Human Gene Therapy. 29, 8, s. 938-949

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. The Role of Hepatic Leukemia Factor in Hematopoiesis

    Komorowska, K., 2018, Lund: Lund University, Faculty of Medicine. 100 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  39. 2017
  40. Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

    Komorowska, K., Alexander Doyle, Martin Wahlestedt, Agatheeswaran Subramaniam, Debnath, S., Jun Chen, Shamit Soneji, Van Handel, B., Mikkola, H. K. A., Kenichi Miharada, David Bryder, Jonas Larsson & Mattias Magnusson, 2017 dec 19, I : Cell Reports. 21, 12, s. 3514-3523 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. Critical Modulation of Hematopoietic Lineage Fate by Hepatic Leukemia Factor

    Martin Wahlestedt, Ladopoulos, V., Isabel Hidalgo, Sanchez Castillo, M., Hannah, R., Petter Säwén, Haixia Wan, Monika Dudenhöffer-Pfeifer, Mattias Magnusson, Norddahl, G. L., Göttgens, B. & David Bryder, 2017 nov 21, I : Cell Reports. 21, 8, s. 2251-2263 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. Signaling via Smad2 and Smad3 is dispensable for adult murine hematopoietic stem cell function in vivo

    Billing, M., Rörby, E., Maria Dahl, Blank, U., Andradottír, S., Mats Ehinger & Stefan Karlsson, 2017 nov, I : Experimental Hematology.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells

    Eriksson, M., Pablo Peña-Martínez, Ramprasad Ramakrishnan, Chapellier, M., Högberg, C., Glowacki, G., Christina Orsmark-Pietras, Velasco-Hernández, T., Lazarević, V. L., Gunnar Juliusson, Cammenga, J., Mulloy, J. C., Johan Richter, Thoas Fioretos, Ebert, B. L. & Marcus Järås, 2017 okt 24, I : Blood Advances. 1, 23, s. 2046-2057 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networks

    Miskinyte, G., Devaraju, K., Grønning Hansen, M., Emanuela Monni, Tornero, D., Niels Bjarne Woods, Johan Bengzon, Henrik Ahlenius, Olle Lindvall & Zaal Kokaia, 2017 sep 29, I : Stem Cell Research and Therapy. 8, 1, 658.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  45. The stem cell regulator PEDF is dispensable for maintenance and function of hematopoietic stem cells

    Rörby, E., Billing, M., Maria Dahl, Sarah Warsi, Andradottir, S., Kenichi Miharada, Siva, K., Jönsson, J-I., Blank, U., Göran Karlsson & Stefan Karlsson, 2017 aug 31, I : Scientific Reports. 7, 10134.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. No increased prevalence of malignancies among first-degree relatives of 800 patients with chronic myeloid leukemia: A population-based study in Sweden

    Gunnarsson, N., Höglund, M., Stenke, L., Sandin, F., Björkholm, M., Dreimane, A., Lambe, M., Markevärn, B., Olsson-Strömberg, U., Wadenvik, H., J. Richter & Själander, A., 2017 aug 1, I : Leukemia. 31, 8, s. 1825-1827 3 s.

    Forskningsoutput: TidskriftsbidragLetter

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