Avdelningen för molekylärmedicin och genterapi

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  1. 2021
  2. BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism

    Lifang Luo, Wenjing Sun, Weijian Zhu, Shuhan Li, Wenqi Zhang, Xiaohui Xu, Daoquan Fang, Tan Hooi Min Grahn, Lei Jiang & Yihu Zheng, 2021 feb, I: Cell Death and Disease. 12, 2, 169.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. Activation of endogenous retroviruses during brain development causes an inflammatory response

    Marie E Jönsson, Raquel Garza, Yogita Sharma, Rebecca Petri, Erik Södersten, Jenny G Johansson, Pia A Johansson, Diahann Am Atacho, Karolina Pircs, Sofia Madsen, David Yudovich, Ramprasad Ramakrishnan, Johan Holmberg, Jonas Larsson, Patric Jern & Johan Jakobsson, 2021, I: EMBO Journal. 40, 9, s. e106423

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. Correction of pathology in mice displaying Gaucher disease type 1 by a clinically-applicable lentiviral vector

    Maria Dahl, Emma M.K. Smith, Sarah Warsi, Michael Rothe, Maria J. Ferraz, Johannes M.F.G. Aerts, Azadeh Golipour, Claudia Harper, Richard Pfeifer, Daniella Pizzurro, Axel Schambach, Chris Mason & Stefan Karlsson, 2021, I: Molecular Therapy - Methods and Clinical Development. 20, s. 312-323 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. Gene therapy for infantile malignant osteopetrosis: review of pre-clinical research and proof-of-concept for phenotypic reversal

    Ilana Moscatelli, Elena Almarza, Axel Schambach, David Ricks, Ansgar Schulz, Christopher D. Herzog, Kim Henriksen, Maria Askmyr, Jonathan D. Schwartz & Johan Richter, 2021, I: Molecular Therapy - Methods and Clinical Development. 20, s. 389-397 9 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  6. In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture

    Simon E. Richardson, Roshanak Ghazanfari, Jyoti Chhetri, Tariq Enver & Charlotta Böiers, 2021, I: STAR Protocols. 2, 2, 100420.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Mitochondrial Potentiation Ameliorates Age-Related Heterogeneity in Hematopoietic Stem Cell Function

    Els Mansell, Valgardur Sigurdsson, Elitza Deltcheva, John Brown, Chela James, Kenichi Miharada, Shamit Soneji, Jonas Larsson & Tariq Enver, 2021, I: Cell Stem Cell. 28, 2, s. 241-256.e6

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. 2020
  9. Så skapar nanoteknik nya vägar till stamcellers inre

    Ludwig Schmiderer, Jonas Larsson & Martin Hjort, 2020 dec 8, Onkologi i Sverige : den oberoende tidningen för svensk cancervård.

    Forskningsoutput: Bidrag till övrig tidskrift/dags- eller nyhetstidningArtikel i facktidskrift eller populärpress

  10. Mononuclear phagocyte regulation by the transcription factor Blimp-1 in health and disease

    Isabel Ulmert, Luís Henriques-Oliveira, Carlos Filipe Pereira & Katharina Lahl, 2020 dec, I: Immunology. 161, 4, s. 303-313 11 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  11. Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171

    Agatheeswaran Subramaniam, Kristijonas Zemaitis, Mehrnaz Safaee Talkhoncheh, David Yudovich, Alexandra Bäckström, Shubhranshu Debnath, Jun Chen, Mayur Vilas Jain, Roman Galeev, Massimiliano Gaetani, Roman A Zubarev & Jonas Larsson, 2020 nov 5, I: Blood. 136, 19, s. 2151-2161 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a

    Mark C. Wilkes, Kavitha Siva, Gianluca Varetti, Jacqueline Mercado, Ethan P. Wentworth, Cristina A. Perez, Mallika Saxena, Sharon Kam, Simryn Kapur, Jun Chen, Anu Narla, Bert Glader, Shou Lin, Manuel Serrano, Johan Flygare & Kathleen M. Sakamoto, 2020 nov 1, I: Experimental Hematology. 91, s. 65-77 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. Transcriptome sequencing identifies a noncoding, deep intronic variant in CLCN7 causing autosomal recessive osteopetrosis

    Odelia Chorin, Naomi Yachelevich, Khaled Mohamed, Ilana Moscatelli, John Pappas, Kim Henriksen & Gilad D. Evrony, 2020 okt 1, I: Molecular Genetics and Genomic Medicine. 8, 10, e1405.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2019

    Darcy E Wagner, Laertis Ikonomou, Sarah E Gilpin, Chelsea M Magin, Fernanda Cruz, Allison Greaney, Mattias Magnusson, Ya-Wen Chen, Brian Davis, Kim Vanuytsel, Sara Rolandsson Enes, Anna Krasnodembskaya, Mareike Lehmann, Gunilla Westergren-Thorsson, John Stegmayr, Hani N Alsafadi, Evan T Hoffman, Daniel J Weiss & Amy L Ryan, 2020 okt, I: ERJ Open Research. 6, 4

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  15. Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency

    Taha Sen, Mayur Jain, Magnus Gram, Alexander Mattebo, Shamit Soneji, Carl R. Walkley & Sofie Singbrant, 2020 aug 1, I: Experimental Hematology. 88, s. 28-41 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. S100A6 is a critical regulator of hematopoietic stem cells.

    Hooi Min Tan Grahn, Abhishek Niroula, Akos Vegvari, Leal Oburoglu, Maroulio Pertesi, Sarah Warsi, Fatemeh Safi, Natsumi Miharada, Sandra C. Garcia, Kavitha Siva, Yang Liu, Emma Rörby, Björn Nilsson, Roman A. Zubarev & Stefan Karlsson, 2020 jun 19, I: Leukemia.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

    Ramprasad Ramakrishnan, Pablo Peña-Martínez, Puneet Agarwal, Maria Rodriguez-Zabala, Marion Chapellier, Carl Högberg, Mia Eriksson, David Yudovich, Mansi Shah, Mats Ehinger, Björn Nilsson, Jonas Larsson, Anna Hagström-Andersson, Benjamin L. Ebert, Ravi Bhatia & Marcus Järås, 2020 maj 26, I: Cell Reports. 31, 8, 107684.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. Generation of gene-corrected functional osteoclasts from osteopetrotic induced pluripotent stem cells

    Xiaojie Xian, Roksana Moraghebi, Henrik Löfvall, Anders Fasth, Kim Henriksen, Johan Richter, Niels Bjarne Woods & Ilana Moscatelli, 2020 maj 15, I: Stem Cell Research & Therapy. 11, 179.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Induction of blood-circulating bile acids supports recovery from myelosuppressive chemotherapy

    Valgardur Sigurdsson, Youichi Haga, Hajime Takei, Els Mansell, Chizuko Okamatsu-Haga, Mitsuyoshi Suzuki, Visnja Radulovic, Mark van der Garde, Shuhei Koide, Svetlana Soboleva, Mats Gåfvels, Hiroshi Nittono, Akira Ohara & Kenichi Miharada, 2020 maj 12, I: Blood Advances. 4, 9, s. 1833-1843 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells

    Hongzhe Li, Hooi Ching Lim, Dimitra Zacharaki, Xiaojie Xian, Keane Jg Kenswil, Sandro Bräunig, Marc Hgp Raaijmakers, Niels-Bjarne Woods, Jenny Hansson & Stefan Scheding, 2020 maj, I: Haematologica. 105, 5, s. 1206-1215 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

    A. Hochhaus, M. Baccarani, R. T. Silver, C. Schiffer, J. F. Apperley, F. Cervantes, R. E. Clark, J. E. Cortes, M. W. Deininger, F. Guilhot, H. Hjorth-Hansen, T. P. Hughes, J. J.W.M. Janssen, H. M. Kantarjian, D. W. Kim, R. A. Larson, J. H. Lipton, F. X. Mahon, J. Mayer, F. Nicolini & 14 andra, D. Niederwieser, F. Pane, J. P. Radich, D. Rea, J. Richter, G. Rosti, P. Rousselot, G. Saglio, S. Saußele, S. Soverini, J. L. Steegmann, A. Turkina, A. Zaritskey & R. Hehlmann, 2020 apr, I: Leukemia. 34, 4, s. 966-984 19 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  22. A SOX2 reporter system identifies gastric cancer stem-like cells sensitive to monensin

    Diana Pádua, Rita Barros, Ana Luísa Amaral, Patrícia Mesquita, Ana Filipa Freire, Mafalda Sousa, André Filipe Maia, Inês Caiado, Hugo Fernandes, António Pombinho, Carlos Filipe Pereira & Raquel Almeida, 2020, I: Cancers. 12, 2, 495.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. Calmodulin inhibitors improve erythropoiesis in Diamond-Blackfan anemia

    Alison M. Taylor, Elizabeth R. Macari, Iris T. Chan, Megan C. Blair, Sergei Doulatov, Linda T. Vo, David M. Raiser, Kavitha Siva, Anindita Basak, Mehdi Pirouz, Arish N. Shah, Katherine McGrath, Jessica M. Humphries, Emma Stillman, Blanche P. Alter, Eliezer Calo, Richard I. Gregory, Vijay G. Sankaran, Johan Flygare, Benjamin L. Ebert & 3 andra, Yi Zhou, George Q. Daley & Leonard I. Zon, 2020, I: Science Translational Medicine. 12, 566, eabb5831.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase

    M. C. Wilkes, K. Siva, J. Chen, G. Varetti, M. Y. Youn, H. Chae, F. Ek, R. Olsson, T. Lundbäck, D. P. Dever, T. Nishimura, A. Narla, B. Glader, H. Nakauchi, M. H. Porteus, C. E. Repellin, H. T. Gazda, S. Lin, M. Serrano, J. Flygare & 1 andra, K. M. Sakamoto, 2020, I: Nature Communications. 11, 1, 3344.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. 2019
  26. Understanding and Modulating Immunity With Cell Reprogramming

    Cristiana F. Pires, Fábio F. Rosa, Ilia Kurochkin & Carlos Filipe Pereira, 2019 dec 11, I: Frontiers in Immunology. 10, 2809.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  27. Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors

    Rita Silvério-Alves, Andreia M. Gomes, Ilia Kurochkin, Kateri A. Moore & Carlos Filipe Pereira, 2019 nov 4, I: Journal of visualized experiments : JoVE. 153

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

    Marie E. Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, Rebecca Petri, David Yudovich, Karolina Pircs, Shana Verschuere, Sofia Madsen, Jenny Hansson, Jonas Larsson, Robert Månsson, Alexander Meissner & Johan Jakobsson, 2019 jul 18, I: Nature Communications. 10, 1, 3182.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells

    Zahra Masoumi, Gregory E. Maes, Koen Herten, Álvaro Cortés-Calabuig, Abdul Ghani Alattar, Eva Hanson, Lena Erlandsson, Eva Mezey, Mattias Magnusson, Joris R. Vermeesch, Mary Familari & Stefan R. Hansson, 2019 apr 25, I: International Journal of Molecular Sciences. 20, 8, 2038.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells

    Praveen Kumar, Dominik Beck, Roman Galeev, Julie A.I. Thoms, Mehrnaz Safaee Talkhoncheh, Ineke de Jong, Ashwin Unnikrishnan, Aurélie Baudet, Agatheeswaran Subramaniam, John E. Pimanda & Jonas Larsson, 2019 feb 26, I: Blood Advances. 3, 4, s. 681-691 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

    Styliani Melissaridou, Emilia Wiechec, Mustafa Magan, Mayur Vilas Jain, Man Ki Chung, Lovisa Farnebo & Karin Roberg, 2019 jan 14, I: Cancer Cell International. 19, 1, 16.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. A dual amylin and calcitonin receptor agonist inhibits pain behavior and reduces cartilage pathology in an osteoarthritis rat model

    A. Katri, A. Dąbrowska, H. Löfvall, M. A. Karsdal, K. V. Andreassen, C. S. Thudium & K. Henriksen, 2019, I: Osteoarthritis and Cartilage. 27, 9, s. 1339-1346

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia

    Kavitha Siva, Fredrik Ek, Jun Chen, Abdul Ghani Alattar, Kristmundur Sigmundsson, Roger Olsson, Marcin Wlodarski, Thomas Lundbäck & Johan Flygare, 2019, I: SLAS Discovery. 24, 3, s. 304-313 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Autoantibodies in Pandemrix®-induced narcolepsy: Nine candidate autoantigens fail the conformational autoantibody test

    Madeleine Wallenius, Alexander Lind, Omar Akel, Emma Karlsson, Markus Svensson, Elin Arvidsson, Anita Ramelius, Carina Törn, Lars Palm, Åke Lernmark & Helena Elding Larsson, 2019, I: Autoimmunity. 52, 4, s. 185-191 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Combining naproxen and a dual amylin and calcitonin receptor agonist improves pain and structural outcomes in the collagen-induced arthritis rat model

    Anna Katri, Aneta Dąbrowska, Henrik Löfvall, Ming Ding, Morten A. Karsdal, Kim V. Andreassen, Christian S. Thudium & Kim Henriksen, 2019, I: Arthritis Research & Therapy. 21, 1, 68.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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