MultiPark: Multidisciplinary research focused on Parkinson´s disease

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  1. Artikel i vetenskaplig tidskrift
  2. Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes

    Limbocker, R., Chia, S., Ruggeri, F. S., Perni, M., Cascella, R., Heller, G. T., Meisl, G., Mannini, B., Habchi, J., Michaels, T. C. T., Challa, P. K., Ahn, M., Casford, S. T., Fernando, N., Xu, C. K., Kloss, N. D., Cohen, S. I. A., Kumita, J. R., Cecchi, C., Zasloff, M. & 5 andraSara Linse, Knowles, T. P. J., Chiti, F., Vendruscolo, M. & Dobson, C. M., 2019 dec 1, I : Nature Communications. 10, 1, 225.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)

    Düzel, E., Acosta-Cabronero, J., Berron, D., Biessels, G. J., Björkman-Burtscher, I., Bottlaender, M., Bowtell, R., Buchem, M. V., Cardenas-Blanco, A., Boumezbeur, F., Chan, D., Clare, S., Costagli, M., de Rochefort, L., Fillmer, A., Gowland, P., Hansson, O., Hendrikse, J., Kraff, O., Ladd, M. E. & 11 andraRonen, I., Petersen, E., Rowe, J. B., Siebner, H., Stoecker, T., Straub, S., Tosetti, M., Uludag, K., Vignaud, A., Zwanenburg, J. & Speck, O., 2019 dec 1, I : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, s. 538-549 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer's and Parkinson's disease

    Sjödin, S., Brinkmalm, G., Öhrfelt, A., Parnetti, L., Paciotti, S., Oskar Hansson, Hardy, J., Blennow, K., Zetterberg, H. & Brinkmalm, A., 2019 sep 14, I : Alzheimer's Research and Therapy. 11, 1, 82.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. The Molecular Chaperone DNAJB6, but Not DNAJB1, Suppresses the Seeded Aggregation of Alpha-Synuclein in Cells

    Deshayes, N., Sertan Arkan & Christian Hansen, 2019 sep 11, I : International Journal of Molecular Sciences. 20, 18, 4495.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. Cardiovascular Disease, Diabetes Mellitus, and Hypertension in Lewy Body Disease: A Comparison with Other Dementia Disorders

    Keivan Javanshiri, Haglund, M. & Elisabet Englund, 2019 aug 20, (Accepted/In press) I : Journal of Alzheimer's disease : JAD. s. 1-9

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Alzheimer's pathology targets distinct memory networks in the ageing brain

    Maass, A., David Berron, Harrison, T. M., Adams, J. N., La Joie, R., Baker, S., Mellinger, T., Bell, R. K., Swinnerton, K., Inglis, B., Rabinovici, G. D., Düzel, E. & Jagust, W. J., 2019 aug 1, I : Brain : a journal of neurology. 142, 8, s. 2492-2509 18 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. Regulator of G-protein signaling 5 regulates the shift from perivascular to parenchymal pericytes in the chronic phase after stroke

    Michaela Roth, Abderahim Gaceb, Andreas Enström, Padel, T., Genové, G., Ozen, I. & Gesine Paul-Visse, 2019 aug, I : FASEB Journal. 33, 8, s. 8990-8998 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Pituitary Metastases: A Nationwide Study on Current Characteristics with Special Reference to Breast Cancer

    Fredrika Schill, Nilsson, M., Olsson, D. S., Ragnarsson, O., Berinder, K., Edén Engström, B., Dahlqvist, P., Wahlberg, J., Elisabet Englund & Pia Burman, 2019 aug, I : Journal of Clinical Endocrinology and Metabolism. 104, 8, s. 3379-3388 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. Low prevalence of known pathogenic mutations in dominant PD genes: A Swedish multicenter study

    Puschmann, A., Jiménez-Ferrer, I., Lundblad-Andersson, E., Mårtensson, E., Hansson, O., Odin, P., Widner, H., Brolin, K., Mzezewa, R., Kristensen, J., Soller, M., Rödström, E. Y., Ross, O. A., Toft, M., Breedveld, G. J., Bonifati, V., Brodin, L., Zettergren, A., Sydow, O., Linder, J. & 6 andraWirdefeldt, K., Svenningsson, P., Nissbrandt, H., Belin, A. C., Forsgren, L. & Maria Swanberg, 2019 jul 31, I : Parkinsonism and Related Disorders.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. α-synuclein−lipoprotein interactions and elevated ApoE level in cerebrospinal fluid from Parkinson’s disease patients

    Paslawski, W., Zareba-Paslawska, J., Zhang, X., Hölzl, K., Wadensten, H., Shariatgorji, M., Shorena Janelidze, Oskar Hansson, Forsgren, L., Andrén, P. E. & Svenningsson, P., 2019 jul 23, I : Proceedings of the National Academy of Sciences of the United States of America. 116, 30, s. 15226-15235 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Determining clinically meaningful decline in preclinical Alzheimer disease

    Philip S. Insel, Weiner, M., Mackin, R. S., Mormino, E., Lim, Y. Y., Erik Stomrud, Sebastian Palmqvist, Masters, C. L., Maruff, P. T., Oskar Hansson & Niklas Mattsson, 2019 jul 23, I : Neurology. 93, 4, s. e322-e333

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. Towards a unified protocol for handling of CSF before β-amyloid measurements

    Shorena Janelidze, Erik Stomrud, Brix, B. & Oskar Hansson, 2019 jul 19, I : Alzheimer's Research and Therapy. 11, 1, 63.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

    Marie E. Jönsson, Ludvik Brattås, P., Gustafsson, C., Petri, R., David Yudovich, Karolina Pircs, Verschuere, S., Madsen, S., Jenny Hansson, Jonas Larsson, Månsson, R., Meissner, A. & Johan Jakobsson, 2019 jul 18, I : Nature Communications. 10, 1, 3182.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. PARK2 mutation causes metabolic disturbances and impaired survival of human iPSC-derived neurons

    Bogetofte, H., Jensen, P., Ryding, M., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M. C., Carla Azevedo, Laurent Roybon, Bak, L. K., Waagepetersen, H., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 2019 jul 5, I : Frontiers in Cellular Neuroscience. 13, 297.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. Associations between quantitative [18F]flortaucipir tau PET and atrophy across the Alzheimer's disease spectrum

    Timmers, T., Rik Ossenkoppele, Wolters, E. E., Verfaillie, S. C. J., Visser, D., Golla, S. S. V., Barkhof, F., Scheltens, P., Boellaard, R., Van Der Flier, W. M. & Van Berckel, B. N. M., 2019 jul 4, I : Alzheimer's Research and Therapy. 11, 1, 60.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

    Ekaterina Savchenko, Teku, G. N., Antonio Boza-Serrano, Kaspar Russ, Berns, M., Tomas Deierborg, Lamas, N. J., Wichterle, H., Rothstein, J., Henderson, C. E., Mauno Vihinen & Laurent Roybon, 2019 jul 3, I : Scientific Reports. 9, 1, 9610.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. Danon disease presenting with early onset of hypertrophic cardiomyopathy and peripheral pigmentary retinal dystrophy in a female with a de novo novel mosaic mutation in the LAMP2 gene

    Monika Meinert, Elisabet Englund, Hedberg-Oldfors, C., Oldfors, A., Kornhall, B., Lundin, C. & Wittström, E., 2019 jul 2, I : Ophthalmic Genetics. 40, 3, s. 227–236 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Prognostic value of Alzheimer’s biomarkers in mild cognitive impairment: the effect of age at onset

    for the Alzheimer’s Disease Neuroimaging Initiative, Altomare, D., Ferrari, C., Caroli, A., Galluzzi, S., Prestia, A., van der Flier, W. M., Ossenkoppele, R., Van Berckel, B., Barkhof, F., Teunissen, C. E., Wall, A., Carter, S. F., Schöll, M., Choo, I. H., Grimmer, T., Redolfi, A., Nordberg, A., Scheltens, P., Drzezga, A. & 1 andraFrisoni, G. B., 2019 jul 2, I : Journal of Neurology.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease

    TRANSEURO consortium, Barker, R. A., Farrell, K., Guzman, N. V., He, X., Lazic, S. E., Moore, S., Morris, R., Tyers, P., Wijeyekoon, R., Daft, D., Hewitt, S., Dayal, V., Foltynie, T., Kefalopoulou, Z., Mahlknecht, P., Lao-Kaim, N. P., Piccini, P., Bjartmarz, H., Björklund, A. & 13 andraOlle Lindvall, Jenny Nelander-Wahlestedt, Malin Parmar, Gesine Paul, Hakan Widner, Church, A., Dunnett, S., Peall, K., Rosser, A., Gurruchaga, J. M., Palfi, S., Piroth, T. & Winkler, C., 2019 jul, I : Nature Medicine. 25, s. 1045–1053 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

    Bonham, L. W., International FTD-Genomics Consortium (IFGC), MARIA LANDQVIST WALDÖ, Nilsson, K., Nilsson, C. & Singleton, A. B., 2019 jul, I : Scientific Reports. 9, 1, 10854 .

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Prevalence of dementia diagnosis not otherwise specified in eight European countries A cross-sectional cohort study

    Connie Lethin, Ingalill Rahm Hallberg, Renom-Guiteras, A., Verbeek, H., Saks, K., Stolt, M., Zabalegui, A., Soto, M. & Nilsson, C., 2019 jun 24, I : BMC Geriatrics. 19, 1, 172.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. Latent Classes of Cognitive Functioning among Depressed Older Adults Without Dementia

    Morin, R. T., Philip Insel, Nelson, C., Butters, M., Bickford, D., Landau, S., Saykin, A., Weiner, M. & Mackin, R. S., 2019 jun 24, I : Journal of the International Neuropsychological Society.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

    IMBI Project, Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Oskar Hansson, Nordberg, A. & Jacobs, A. H., 2019 jun 21, I : Alzheimer's and Dementia.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. Disease stage dependency of motor and non-motor fluctuations in Parkinson's disease

    NoMoFlu-PD Study Group, Storch, A., Kristina Rosqvist, Ebersbach, G. & Per Odin, 2019 jun 19, I : Journal of Neural Transmission.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. Atrophic Myenteric and Submucosal Neurons Are Observed in Parkinson's Disease

    Bodil Ohlsson & Elisabet Englund, 2019 jun 19, I : Parkinson's Disease. 2019, 5 s., 7935820.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus

    David Ermert, Laabei, M., Weckel, A., Mörgelin, M., Martin Lundqvist, Lars Björck, Ram, S., Sara Linse & Anna M. Blom, 2019 jun 4, I : Frontiers in Immunology. 10, JUN, 1230.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

    Alzheimer's Disease Neuroimaging Initiative, AIBL Research Group, Vermunt, L., Åsa Wallin & Visser, P-J., 2019 jun 1, I : Alzheimer's and Dementia.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia

    Meeter, L. H. H., Steketee, R. M. E., Salkovic, D., Vos, M. E., Grossman, M., McMillan, C. T., Irwin, D. J., Boxer, A. L., Rojas, J. C., Olney, N. T., Karydas, A., Miller, B. L., Pijnenburg, Y. A. L., Barkhof, F., Sánchez-Valle, R., Lladó, A., Borrego-Ecija, S., Diehl-Schmid, J., Grimmer, T., Goldhardt, O. & 27 andraAlexander F. Santillo, Oskar Hansson, Susanne Vestberg, Borroni, B., Padovani, A., Galimberti, D., Scarpini, E., Rohrer, J. D., Woollacott, I. O. C., Synofzik, M., Wilke, C., De Mendonca, A., Vandenberghe, R., Benussi, L., Ghidoni, R., Binetti, G., Niessen, W. J., Papma, J. M., Seelaar, H., Jiskoot, L. C., De Jong, F. J., Donker Kaat, L., Del Campo, M., Teunissen, C. E., Bron, E. E., Van Den Berg, E. & Van Swieten, J. C., 2019 maj 28, I : Journal of Neurology, Neurosurgery and Psychiatry. 8 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. Elecsys® Total-Tau and Phospho-Tau (181P) CSF assays: Analytical performance of the novel, fully automated immunoassays for quantification of tau proteins in human cerebrospinal fluid

    Lifke, V., Kollmorgen, G., Manuilova, E., Oelschlaegel, T., Hillringhaus, L., Widmann, M., von Arnim, C. A. F., Otto, M., Christenson, R. H., Powers, J. L., Shaw, L. M., Oskar Hansson, Doecke, J. D., Li, Q. X., Teunissen, C., Tumani, H. & Blennow, K., 2019 maj 23, I : Clinical Biochemistry.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. Method comparison study of the Elecsys® β-Amyloid (1–42) CSF assay versus comparator assays and LC-MS/MS

    Shaw, L. M., Oskar Hansson, Manuilova, E., Masters, C. L., Doecke, J. D., Li, Q. X., Rutz, S., Widmann, M., Leinenbach, A. & Blennow, K., 2019 maj 23, I : Clinical Biochemistry.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. Global and domain-specific life satisfaction among older adults with long-term spinal cord injury

    Sophie Jörgensen, Hedgren, L., Sundelin, A. & Jan Lexell, 2019 maj 17, I : Journal of Spinal Cord Medicine.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study

    Rongve, A., Witoelar, A., Ruiz, A., Athanasiu, L., Abdelnour, C., Clarimon, J., Heilmann-Heimbach, S., Hernández, I., Moreno-Grau, S., de Rojas, I., Morenas-Rodríguez, E., Fladby, T., Sando, S. B., Bråthen, G., Blanc, F., Bousiges, O., Lemstra, A. W., van Steenoven, I., Londos, E., Almdahl, I. S. & 20 andraPålhaugen, L., Eriksen, J. A., Djurovic, S., Stordal, E., Saltvedt, I., Ulstein, I. D., Bettella, F., Desikan, R. S., Idland, A. V., Toft, M., Pihlstrøm, L., Snaedal, J., Tárraga, L., Boada, M., Lleó, A., Stefánsson, H., Stefánsson, K., Ramírez, A., Aarsland, D. & Andreassen, O. A., 2019 maj 7, I : Scientific Reports. 9, 1, 7013.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Integrin α10, a novel therapeutic target in glioblastoma, regulates cell migration, proliferation, and survival

    Thorén, M. M., Masoumi, K. C., Krona, C., Huang, X., Kundu, S., Schmidt, L., Forsberg-Nilsson, K., Keep, M. F., Elisabet Englund, Nelander, S., Holmqvist, B. & Lundgren-Åkerlund, E., 2019 apr 25, I : Cancers. 11, 4, 587.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. The Physical Housing Environment and Subjective Well-Being Among Older People Using Long-Term Care Services in Japan

    Tsuchiya-Ito, R., Björn Slaug & Ishibashi, T., 2019 apr 22, I : Journal of Housing for the Elderly.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. Association between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients with Alzheimer Disease

    Niklas Mattsson, Cullen, N. C., Andreasson, U., Zetterberg, H. & Blennow, K., 2019 apr 22, I : JAMA Neurology.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. 18 F-Flortaucipir in TDP-43 associated frontotemporal dementia

    R. Smith, A. F. Santillo, M. Landqvist Waldö, O. Strandberg, D. Berron, S. Vestberg, D. van Westen, van Swieten, J., Honer, M. & O. Hansson, 2019 apr 15, I : Scientific Reports. 9, 1, 6082.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism

    Sjöström, H., Yulia Surova, Markus Nilsson, Granberg, T., Westman, E., Danielle van Westen, Svenningsson, P. & Oskar Hansson, 2019 apr 15, I : Scientific Reports. 9, 1, 6079.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  39. Relocation of coflowing immiscible liquids under acoustic field in a microchannel

    Hemachandran, E., Karthick, S., T. Laurell & Sen, A. K., 2019 apr 15, I : EPL. 125, 5, 54002.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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