Stamcellscentrum (SCC)

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  1. Artikel i vetenskaplig tidskrift
  2. The prognostic impact of FLT3-ITD and NPM1 mutation in adult AML is age-dependent in the population-based setting

    Gunnar Juliusson, Jädersten, M., Deneberg, S., Lehmann, S., Möllgård, L., Wennström, L., Antunovic, P., Cammenga, J., Lorenz, F., Ölander, E., Lazarevic, V. L. & Höglund, M., 2020 mar 24, I : Blood Advances. 4, 6, s. 1094-1101

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. The NF-κB modulated miR-194-5p/IGF1R/PPFIBP axis is crucial for the tumorigenesis of ovarian cancer

    Bai, R., Dou, K., Wu, Y., Ma, Y. & Jianmin Sun, 2020 mar 13, I : Journal of Cancer. 11, 12, s. 3433-3445 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. Loss of PI3 kinase association improves the sensitivity of secondary mutation of KIT to Imatinib

    Zhu, G., Shi, J., Zhang, S., Guo, Y., Huang, L., Zhao, H., Jiang, Y. & Jianmin Sun, 2020 feb 12, I : Cell and Bioscience. 10, 1, 16.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants

    Korchynska, S., Krassnitzer, M., Malenczyk, K., Prasad, R. B., Tretiakov, E. O., Rehman, S., Cinquina, V., Gernedl, V., Farlik, M., Petersen, J., Hannes, S., Schachenhofer, J., Reisinger, S. N., Zambon, A., Asplund, O., Artner, I., Keimpema, E., Lubec, G., Mulder, J., Bock, C. & 6 andra, Pollak, D. D., Romanov, R. A., Pifl, C., Leif Groop, Hökfelt, T. G. & Harkany, T., 2020 jan 2, I : EMBO Journal. 39, 1, e100882.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. Outcome and characteristics of non-measurable myeloma: A cohort study with population-based data from the Swedish Myeloma Registry

    Wålinder, G., Samuelsson, J., Näsman, P., Markus Hansson, Gunnar Juliusson, Forsberg, K., Svensson, R., Linder, O., Carlson, K., Kristinsson, S. Y., Mellqvist, U. H., Hveding Blimark, C., Ingemar Turesson & Nahi, H., 2020, I : European Journal of Haematology. 104, 5, s. 376-382 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

    Dwivedi, O. P., Lehtovirta, M., Hastoy, B., Chandra, V., Krentz, N. A. J., Kleiner, S., Jain, D., Richard, A-M., Abaitua, F., Beer, N. L., Grotz, A., Prasad, R. B., Hansson, O., Ahlqvist, E., Krus, U., Artner, I., Suoranta, A., Gomez, D., Baras, A., Champon, B. & 27 andra, Payne, A. J., Moralli, D., Thomsen, S. K., Kramer, P., Spiliotis, I., Ramracheya, R., Chabosseau, P., Theodoulou, A., Cheung, R., Van De Bunt, M., Flannick, J., Trombetta, M., Bonora, E., Wolheim, C. B., Sarelin, L., Bonadonna, R. C., Rorsman, P., Davies, B., Brosnan, J., Mccarthy, M. I., Otonkoski, T., Jens O. Lagerstedt, Rutter, G. A., Gromada, J., Gloyn, A. L., Tuomi, T. & Leif Groop, 2019 nov 1, I : Nature Genetics. s. 1-22

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts

    Angenendt, L., Röllig, C., Montesinos, P., Martínez-Cuadrón, D., Barragan, E., García, R., Botella, C., Martínez, P., Ravandi, F., Kadia, T., Kantarjian, H. M., Cortes, J., Juliusson, G., Lazarevic, V., Recher, C., Pigneux, A., Bertoli, S., Dumas, P. Y., Dombret, H., Preudhomme, C. & 23 andra, Micol, J. B., Terré, C., Ráčil, Z., Novák, J., Žák, P., Wei, A. H., Tiong, I. S., Wall, M., Estey, E., Shaw, C., Exeler, R., Wagenführ, L., Stölzel, F., Thiede, C., Stelljes, M., Lenz, G., Mikesch, J. H., Serve, H., Ehninger, G., Berdel, W. E., Kramer, M., Krug, U. & Schliemann, C., 2019 okt 10, I : Journal of Clinical Oncology. 37, 29, s. 2632-2642

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Loss of MafA and MafB expression promotes islet inflammation.

    Tania Singh, Colberg, J. K., Luis Sarmiento, Chaves, P., Hansen, L., Bsharat, S., Luis R. Cataldo, Monika Dudenhöffer-Pfeifer, Malin Fex, David Bryder, Dan Holmberg, Ewa Sitnicka, Corrado Cilio, Rashmi B. Prasad & Isabella Artner, 2019 jun 24, I : Scientific Reports. 9, 1, 9074.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma

    Jain, N., Hartert, K., Tadros, S., Fiskus, W., Havranek, O., Ma, M. C. J., Bouska, A., Heavican, T., Kumar, D., Deng, Q., Moore, D., Pak, C., Liu, C. L., Gentles, A. J., Hartmann, E., Kridel, R., Smedby, K. E., Juliusson, G., Rosenquist, R., Gascoyne, R. D. & 13 andra, Rosenwald, A., Giancotti, F., Neelapu, S. S., Westin, J., Vose, J. M., Lunning, M. A., Greiner, T., Rodig, S., Iqbal, J., Alizadeh, A. A., Davis, R. E., Bhalla, K. & Green, M. R., 2019 jun 19, I : Science Translational Medicine. 11, 497, eaav5599.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death

    Ajmone-Cat, M. A., Onori, A., Toselli, C., Stronati, E., Morlando, M., Bozzoni, I., Emanuela Monni, Zaal Kokaia, Lupo, G., Minghetti, L., Biagioni, S. & Cacci, E., 2019 mar 14, I : Scientific Reports. 9, 1, 4572.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Generation of Human 3D Lung Tissue Cultures (3D-LTCs) for Disease Modeling

    Gerckens, M., Hani N Alsafadi, Darcy E Wagner, Lindner, M., Burgstaller, G. & Königshoff, M., 2019 feb 12, I : Journal of visualized experiments : JoVE. 144, e58437 .

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. Cell-based therapy for Parkinson's disease: A journey through decades toward the light side of the Force

    Malin Parmar, Torper, O. & Drouin-Ouellet, J., 2019, I : European Journal of Neuroscience. 49, 4, s. 463-471

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. Safety and Effectiveness of Vedolizumab in Patients with Steroid-Refractory GI Acute GvHD: A Retrospective Record Review

    Fløisand, Y., Lazarevic, V. L., Maertens, J., Mattsson, J., Shah, N. N., Zachée, P., Taylor, A., Akbari, M., Quadri, S., Parfionovas, A. & Chen, Y., 2019, I : Biology of Blood and Marrow Transplantation. 25, 4, s. 720-727

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. In Vitro Functional Characterization of Human Neurons and Astrocytes Using Calcium Imaging and Electrophysiology

    Hansen, M. G., Tornero, D., Isaac Canals, Henrik Ahlenius & Zaal Kokaia, 2019, I : Methods in molecular biology (Clifton, N.J.). 1919, s. 73-88 16 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia

    Baliakas, P., Moysiadis, T., Hadzidimitriou, A., Xochelli, A., Jeromin, S., Agathangelidis, A., Mattsson, M., Sutton, L. A., Minga, E., Scarfò, L., Rossi, D., Davis, Z., Villamor, N., Parker, H., Kotaskova, J., Stalika, E., Plevova, K., Mansouri, L., Cortese, D., Navarro, A. & 20 andra, Delgado, J., Larrayoz, M., Young, E., Anagnostopoulos, A., Smedby, K. E., Gunnar Juliusson, Sheehy, O., Catherwood, M., Strefford, J. C., Stavroyianni, N., Belessi, C., Pospisilova, S., Oscier, D., Gaidano, G., Campo, E., Haferlach, C., Ghia, P., Rosenquist, R., Stamatopoulos, K. & European Research Initiative on CLL (ERIC), 2019, I : Haematologica. 104, 2, s. 360-369 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors

    Yonathan Sonntag, Gena, P., Maggio, A., Tania Singh, Isabella Artner, Oklinski, M. K., Urban Johanson, Per Kjellbom, Nieland, J. D., Nielsen, S., Calamita, G. & Rützler, M., 2019, I : Journal of Biological Chemistry. 294, 18, s. 7377-7387 20 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. Platelet Serotonin Levels Are Associated with Plasma Soluble Leptin Receptor Concentrations in Normoglycemic Women

    Rodrigo Cataldo Buscunan, Suazo, J., Olmos, P., Bravo, C., Galgani, J. E., Malin Fex, Martínez, J. A. & Santos, J. L., 2019, I : Journal of Diabetes Research. 2019, 11 s., 2714049.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Putative Role of Nuclear Factor-Kappa B But Not Hypoxia-Inducible Factor-1α in Hypoxia-Dependent Regulation of Oxidative Stress in Hematopoietic Stem and Progenitor Cells

    Halvarsson, C., Rörby, E., Eliasson, P., Stefan Lang, Shamit Soneji & Jönsson, J. I., 2019, I : Antioxidants and Redox Signaling. 31, 3, s. 211-226 16 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Secondary Acute Myeloid Leukemia and the Role of Allogeneic Stem Cell Transplantation in a Population-Based Setting

    Nilsson, C., Hulegårdh, E., Garelius, H., Möllgård, L., Brune, M., Wahlin, A., Lenhoff, S., Frödin, U., Remberger, M., Höglund, M., Gunnar Juliusson, Stockelberg, D. & Lehmann, S., 2019, I : Biology of Blood and Marrow Transplantation. 25, 9, s. 1770-1778

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

    Went, M., Sud, A., Speedy, H., Sunter, N. J., Försti, A., Law, P. J., Johnson, D. C., Mirabella, F., Holroyd, A., Li, N., Orlando, G., Weinhold, N., van Duin, M., Chen, B., Mitchell, J. S., Mansouri, L., Juliusson, G., Smedby, K. E., Jayne, S., Majid, A. & 35 andra, Dearden, C., Allsup, D. J., Bailey, J. R., Pratt, G., Pepper, C., Fegan, C., Rosenquist, R., Kuiper, R., Stephens, O. W., Bertsch, U., Broderick, P., Einsele, H., Gregory, W. M., Hillengass, J., Hoffmann, P., Jackson, G. H., Jöckel, K. H., Nickel, J., Nöthen, M. M., da Silva Filho, M. I., Hauke Thomsen, Walker, B. A., Broyl, A., Davies, F. E., Markus Hansson, Goldschmidt, H., Dyer, M. J. S., Kaiser, M., Sonneveld, P., Morgan, G. J., Kari Hemminki, Björn Nilsson, Catovsky, D., Allan, J. M. & Houlston, R. S., 2018 dec 21, I : Blood Cancer Journal. 9, 1, 1.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

    Petter Säwen, Mohamed Eldeeb, Eva Erlandsson, Trine A. Kristiansen, Laterza, C., Zaal Kokaia, Göran Karlsson, Joan Yuan, Shamit Soneji, Mandal, P. K., Rossi, D. J. & David Bryder, 2018 dec 18, I : eLife. 7, e41258.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

    Hyrenius-Wittsten, A., Pilheden, M., Sturesson, H., Hansson, J., Walsh, M. P., Song, G., Kazi, J. U., Liu, J., Ramakrishan, R., Garcia-Ruiz, C., Nance, S., Gupta, P., Zhang, J., Rönnstrand, L., Hultquist, A., Downing, J. R., Lindkvist-Petersson, K., Paulsson, K., Järås, M., Gruber, T. A. & 2 andra, Ma, J. & Anna K. Hagström-Andersson, 2018 dec 1, I : Nature Communications. 9, 1, 1770.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  24. MafA expression preserves immune homeostasis in human and mouse islets

    Tania Singh, Luis Sarmiento, Cheng Luan, Rashmi B. Prasad, Johansson, J., Luis R. Cataldo, Erik Renström, Shamit Soneji, Corrado Cilio & Isabella Artner, 2018 dec 1, I : Genes. 9, 12, 644.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. The MYC/Max/MxD network is a target of mutated FLT3 signaling in hematopoietic stem cells in FLT3-ITD-induced myeloproliferative disease

    Basit, F., Andersson, M. & Anne Hultquist, 2018 okt 21, I : Stem Cells International. 2018, 3286949.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers

    Miskinyte, G., Hansen, M. G., Emanuela Monni, Lam, M., Johan Bengzon, Olle Lindvall, Henrik Ahlenius & Zaal Kokaia, 2018 okt 11, I : PLoS ONE. 13, 10, e0204688.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. The immunomodulatory quinoline-3-carboxamide paquinimod reverses established fibrosis in a novel mouse model for liver fibrosis

    Fransén Pettersson, N., Deronic, A., Julia Nilsson, Hannibal, T., Hansen, L., Anja Schmidt-Christensen, Fredrik Ivars & Dan Holmberg, 2018 sep 5, I : PLoS ONE. 13, 9, e0203228.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. Dynamic expression of HOPX in alveolar epithelial cells reflects injury and repair during the progression of pulmonary fibrosis

    Ota, C., Ng-Blichfeldt, J-P., Korfei, M., Hani N. Alsafadi, Lehmann, M., Skronska-Wasek, W., Martina M. De Santis, Guenther, A., Darcy Wagner & Königshoff, M., 2018 aug 28, I : Scientific Reports. 8, 12983.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. Co-opting of ClinicalTrials.gov by patient-funded studies

    Darcy E. Wagner, Turner, L., Panoskaltsis-Mortari, A., Weiss, D. J. & Ikonomou, L., 2018 aug, I : The Lancet Respiratory Medicine. 6, 8, s. 579-581

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. Acellular human lung scaffolds to model lung disease and tissue regeneration

    Gilpin, S. E. & Darcy E. Wagner, 2018 jun 30, I : European Respiratory Review. 27, 148, 180021.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. XK-related protein 5 (XKR5) is a novel negative regulator of KIT/D816V-mediated transformation

    Jianmin Sun, Thingholm, T., Højrup, P. & Lars Rönnstrand, 2018 jun 1, I : Oncogenesis. 7, 6, 00573.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. Generation of a human induced pluripotent stem cell line (CSC-40) from a Parkinson's disease patient with a PINK1 p.Q456X mutation

    Kaspar Russ, Marote, A., Ekaterina Savchenko, Collin, A., Goldwurm, S., Yuriy Pomeshchik & Laurent Roybon, 2018 mar 1, I : Stem Cell Research. 27, s. 61-64 4 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. Generation of an integration-free induced pluripotent stem cell line (CSC-43J) from a patient with sporadic Parkinson's disease

    Marote, A., Yuriy Pomeshchik, Goldwurm, S., Collin, A., Lamas, N. J., Pinto, L., Salgado, A. J. & Laurent Roybon, 2018 mar 1, I : Stem Cell Research. 27, s. 82-85 4 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease

    Ekaterina Savchenko, Marote, A., Kaspar Russ, Collin, A., Goldwurm, S., Laurent Roybon & Yuriy Pomeshchik, 2018 mar 1, I : Stem Cell Research. 27, s. 78-81 4 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Outcome and survival of myeloma patients diagnosed 2008-2015. Real-world data on 4904 patients from the Swedish Myeloma Registry

    Blimark, C. H., Ingemar Turesson, Genell, A., Ahlberg, L., Björkstrand, B., Carlson, K., Forsberg, K., Gunnar Juliusson, Linder, O., Mellqvist, U. H., Nahi, H. & Kristinsson, S. Y., 2018 feb 28, I : Haematologica. 103, 3, s. 506-513

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1

    Charlotta Böiers, Richardson, S. E., Laycock, E., Zriwil, A., Turati, V. A., Brown, J., Wray, J. P., Wang, D., James, C., Herrero, J., Ewa Sitnicka, Stefan Karlsson, Smith, A. J. H., Jacobsen, S. E. W. & Tariq Enver, 2018 feb 5, I : Developmental Cell. 44, 3, s. 362-377.e7

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. Gene expression of the two developmentally regulated dermatan sulfate epimerases in the Xenopus embryo

    Gouignard, N., Schön, T., Christian Holmgren, Strate, I., Taşöz, E., Wetzel, F., Maccarana, M. & Edgar M. Pera, 2018 jan 1, I : PLoS ONE. 13, 1, e0191751.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. Customized brain cells for stroke patients using pluripotent stem cells

    Zaal Kokaia, Llorente, I. L. & Carmichael, S. T., 2018 jan 1, I : Stroke. 49, 5, s. 1091-1098 8 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  39. Relatively favorable outcome after allogeneic stem cell transplantation for BCR-ABL1-positive AML: A survey from the acute leukemia working party of the European Society for blood and marrow transplantation (EBMT)

    Lazarevic, V. L., Labopin, M., Depei, W., Yakoub-Agha, I., Huynh, A., Ljungman, P., Schaap, N., Cornelissen, J. J., Maillard, N., Pioltelli, P., Gedde-Dahl, T., Lenhoff, S., Houhou, M., Esteve, J., Mohty, M. & Nagler, A., 2018, I : American Journal of Hematology. 93, 1, s. 31-39

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  40. Acoustofluidic hematocrit determination

    Klara Petersson, Jakobsson, O., Pelle Ohlsson, Per Augustsson, Stefan Scheding, Johan Malm & Thomas Laurell, 2018, I : Analytica Chimica Acta. 1000, s. 199-204

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. Internal tandem duplication mutations in the tyrosine kinase domain of FLT3 display a higher oncogenic potential than the activation loop D835Y mutation

    Marhäll, A., Heidel, F., Fischer, T. & Lars Rönnstrand, 2018, I : Annals of Hematology. 97, 5, s. 773-780

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells

    Guzzi, N., Cieśla, M., Ngoc, P. C. T., Lang, S., Arora, S., Dimitriou, M., Pimková, K., Sommarin, M. N. E., Munita, R., Lubas, M., Lim, Y., Okuyama, K., Soneji, S., Karlsson, G., Hansson, J., Jönsson, G., Lund, A. H., Sigvardsson, M., Hellström-Lindberg, E., Hsieh, A. C. & 1 andra, Cristian Bellodi, 2018, I : Cell. 173, 5, s. 1204-1216.e26

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Acute myeloid leukemia in very old patients

    Lazarevic, V. L., Anders Bredberg, Lorenz, F., Ölander, E., Antunovic, P., Cammenga, J., Wennström, L., Möllgård, L., Deneberg, S., Derolf, Å., Höglund, M. & Gunnar Juliusson, 2018, I : Haematologica. 103, 12, s. e578-e580

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, J., Aurélie Baudet, Abelechian, S., Bonderup, K., d'Altri, T., Porse, B., Brakebusch, C., Gunnar Juliusson & Cammenga, J., 2018, I : Genesis. 56, 9, e23238.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  45. Acoustic Enrichment of Extracellular Vesicles from Biological Fluids

    Anson Ku, Hooi Ching Lim, Mikael Evander, Lilja, H., Thomas Laurell, Stefan Scheding & Yvonne Ceder, 2018, I : Analytical Chemistry. 90, 13, s. 8011-8019 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

    Göran Karlsson, Mikael Sigvardsson & Charlotta Böiers, 2017 dec 15, I : EMBO Journal. 36, 24, s. 3552-3554 3 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes

    Rostami, J., Holmqvist, S., Lindström, V., Sigvardson, J., Westermark, G. T., Ingelsson, M., Bergström, J., Laurent Roybon & Erlandsson, A., 2017 dec 6, I : Journal of Neuroscience. 37, 49, s. 11835-11853 19 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. The Src family kinase LCK cooperates with oncogenic FLT3/ITD in cellular transformation

    Marhäll, A., Julhash U. Kazi & Lars Rönnstrand, 2017 dec 1, I : Scientific Reports. 7, 1, 13734.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. A new approach for ratiometric in vivo calcium imaging of microglia

    Brawek, B., Liang, Y., Savitska, D., Li, K., Fomin-Thunemann, N., Kovalchuk, Y., Zirdum, E., Johan Jakobsson & Garaschuk, O., 2017 dec 1, I : Scientific Reports. 7, 1, 6030.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  50. EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity

    Löf-Öhlin, Z. M., Nyeng, P., Bechard, M. E., Hess, K., Bankaitis, E., Greiner, T. U., Ameri, J., Wright, C. V. & Semb, H., 2017 nov 1, I : Nature Cell Biology. 19, 11, s. 1313-1325 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells

    Eriksson, M., Pablo Peña-Martínez, Ramprasad Ramakrishnan, Chapellier, M., Högberg, C., Glowacki, G., Christina Orsmark-Pietras, Velasco-Hernández, T., Lazarević, V. L., Gunnar Juliusson, Cammenga, J., Mulloy, J. C., Johan Richter, Thoas Fioretos, Ebert, B. L. & Marcus Järås, 2017 okt 24, I : Blood Advances. 1, 23, s. 2046-2057 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. Chronic lymphocytic leukemia with mutated IGHV4-34 receptors: Shared and distinct immunogenetic features and clinical outcomes

    Xochelli, A., Baliakas, P., Kavakiotis, I., Agathangelidis, A., Sutton, L-A., Minga, E., Ntoufa, S., Tausch, E., Yan, X-J., Shanafelt, T., Plevova, K., Boudjogra, M., Rossi, D., Davis, Z., Navarro, A., Sandberg, Y., Vojdeman, F. J., Scarfo, L., Stavroyianni, N., Sudarikov, A. & 42 andra, Veronese, S., Tzenou, T., Karan-Djurasevic, T., Catherwood, M., Kienle, D., Chatzouli, M., Facco, M., Bahlo, J., Pott, C., Pedersen, L. B., Mansouri, L., Smedby, K. E., Chu, C. C., Giudicelli, V., Lefranc, M-P., Panagiotidis, P., Gunnar Juliusson, Anagnostopoulos, A., Vlahavas, I., Antic, D., Trentin, L., Montillo, M., Niemann, C., Dohner, H., Langerak, A. W., Pospisilova, S., Hallek, M., Campo, E., Chiorazzi, N., Maglaveras, N., Oscier, D., Gaidano, G., Jelinek, D. F., Stilgenbauer, S., Chouvarda, I., Darzentas, N., Belessi, C., Davi, F., Hadzidimitriou, A., Rosenquist, R., Ghia, P. & Stamatopoulos, K., 2017 sep 1, I : Clinical Cancer Research. 23, 17, s. 5292-5301 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  53. Incidence, characteristics, and outcome of solitary plasmacytoma and plasma cell leukemia. Population-based data from the Swedish Myeloma Register

    Nahi, H., Genell, A., Wålinder, G., Uttervall, K., Gunnar Juliusson, Karin, F., Markus Hansson, Svensson, R., Linder, O., Carlson, K., Björkstrand, B., Kristinsson, S. Y., Mellqvist, U-H., Blimark, C. & Ingemar Turesson, 2017 sep, I : European Journal of Haematology. 99, 3, s. 216-222

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  54. Age but not Philadelphia positivity impairs outcome in older/elderly patients with acute lymphoblastic leukemia in Sweden

    Kozlowski, P., Lennmyr, E., Ahlberg, L., Bernell, P., Hulegårdh, E., Karbach, H., Karlsson, K., Tomaszewska-Toporska, B., Åström, M., Hallböök, H. & the Swedish Adult Acute Lymphoblastic Leukemia Group (SVALL), 2017 aug 1, I : European Journal of Haematology. 99, 2, s. 141-149 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  55. Leukotriene signaling via ALOX5 and cysteinyl leukotriene receptor 1 is dispensable for in vitro growth of CD34+CD38- stem and progenitor cells in chronic myeloid leukemia

    Dolinska, M., Piccini, A., Wong, W. M., Gelali, E., Johansson, A. S., Klang, J., Xiao, P., Yektaei-Karin, E., Strömberg, U. O., Mustjoki, S., Stenke, L., Marja Ekblom & Qian, H., 2017 aug, I : Biochemical and Biophysical Research Communications. 490, 2, s. 378-384

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  56. Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep

    Alexandra Rundberg Nilsson & Kees-Jan Pronk, 2017 jul 6, I : Cell Stem Cell. 21, 1, s. 9-11 3 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  57. Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes

    Axelsson, A., Mahdi, T., Nenonen, H. A., Singh, T., Hänzelmann, S., Wendt, A., Bagge, A., Reinbothe, T. M., Millstein, J., Yang, X., Zhang, B., Gusmao, E. G., Shu, L., Szabat, M., Tang, Y., Wang, J., Salö, S., Eliasson, L., Artner, I., Fex, M. & 9 andra, J D Johnson, C B Wollheim, Derry, J. M. J., Mecham, B., P Spégel, H Mulder, Costa, I. G., E Zhang & Rosengren, A. H., 2017 jun 6, I : Nature Communications. 8, s. 15652

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  58. Leptin/Adiponectin Ratios Using Either Total Or High-Molecular-Weight Adiponectin as Biomarkers of Systemic Insulin Sensitivity in Normoglycemic Women

    Bravo, C., Luis Rodrigo Cataldo , Galgani, J., Parada, J. & Santos, J. L., 2017 maj 25, I : Journal of Diabetes Research. s. 1-12 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  59. The dual specificity PI3K/mTOR inhibitor PKI-587 displays efficacy against T-cell acute lymphoblastic leukemia (T-ALL)

    Mohiuddin, G., Sausan A. Moharram, Marhäll, A. & Julhash U. Kazi, 2017 apr 28, I : Cancer Letters. 392, s. 9-16 8 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  60. Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2+ Human Pancreatic Progenitors

    Ameri, J., Borup, R., Prawiro, C., Ramond, C., Schachter, K. A., Scharfmann, R. & Semb, H., 2017 apr 4, I : Cell Reports. 19, 1, s. 36-49 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  61. Single-cell molecular analysis defines therapy response and immunophenotype of stem cell subpopulations in CML

    Rebecca Warfvinge, Linda Geironson Ulfsson, Mikael N E Sommarin, Stefan Lang, Christine Karlsson, Roschupkina, T., Stenke, L., Stentoft, J., Olsson-Strömberg, U., Hjorth-Hansen, H., Mustjoki, S., Shamit Soneji, Johan Richter & Göran Karlsson, 2017 apr, I : Blood. 129, 17, s. 2384-2394

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  62. A single-arm, open-label, phase 2 clinical trial evaluating disease response following treatment with BI-505, a human anti-intercellular adhesion molecule-1 monoclonal antibody, in patients with smoldering multiple myeloma

    Stina Wichert, Gunnar Juliusson, Johansson, Å., Sonesson, E., Teige, I., Wickenberg, A. T., Frendeus, B., Korsgren, M. & Markus Hansson, 2017 feb 1, I : PLoS ONE. 12, 2, e0171205.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  63. Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson's Disease

    Agnete Kirkeby, Sara Nolbrant, Tiklova, K., Andreas Heuer, Kee, N., Cardoso, T., Daniella Rylander Ottosson, Lelos, M. J., Rifes, P., Dunnett, S. B., Grealish, S., Perlmann, T. & Malin Parmar, 2017 jan 5, I : Cell Stem Cell. 20, 1, s. 135-148 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  64. Identification of two distinct mesenchymal stromal cell populations in human malignant glioma

    Andreas Svensson, Tania Ramos-Moreno, Eberstål, S., Stefan Scheding & Johan Bengzon, 2017 jan, I : Journal of Neuro-Oncology. 131, 2, s. 245-254

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  65. Memory formation orchestrates the wiring of adult-born hippocampal neurons into brain circuits

    Petsophonsakul, P., Richetin, K., Andraini, T., Laurent Roybon & Rampon, C., 2017, I : Brain Structure and Function. 222, 6, s. 2585-2601

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  66. ABL2 suppresses FLT3-ITD-induced cell proliferation through negative regulation of AKT signaling

    Julhash U Kazi, Rupar, K., Marhäll, A., Sausan A Moharram, Khanum, F., Kinjal Shah, Mohiuddin, G., Mysore Nagaraj, S. R., Jianmin Sun, Chougule, R. A. & Lars Rönnstrand, 2017, I : Oncotarget. 8, 7, s. 12194-12202

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  67. Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population-based study from the Swedish AML registry

    Lj Lazarevic, V., Aldana Rosso, Gunnar Juliusson, Antunovic, P., Derolf, Å. R., Deneberg, S., Möllgård, L., Uggla, B., Wennström, L., Wahlin, A., Höglund, M., Lehmann, S. & Bertil Johansson, 2017, I : European Journal of Haematology. 98, 5, s. 493-500

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  68. A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network

    Unnikrishnan, A., Guan, Y. F., Huang, Y., Beck, D., Thoms, J. A. I., Peirs, S., Knezevic, K., Ma, S., de Walle, I. V., Ineke de Jong, Ali, Z., Zhong, L., Raftery, M. J., Taghon, T., Jonas Larsson, MacKenzie, K. L., Van Vlierberghe, P., Wong, J. W. H. & Pimanda, J. E., 2016 dec 15, I : Nucleic Acids Research. 44, 22, s. 10644-10661

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  69. IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

    Helena Ågerstam, Hansen, N., Sofia von Palffy, Carl Sandén, Reckzeh, K., Christine Karlsson, Henrik Lilljebjörn, Niklas Landberg, Askmyr, M., Högberg, C., Rissler, M., Porkka, K., Wadenvik, H., Mustjoki, S., Johan Richter, Marcus Järås & Thoas Fioretos, 2016 dec 8, I : Blood. 128, 23, s. 2683-2693

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  70. Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors

    Luis, T. C., Luc, S., Mizukami, T., Boukarabila, H., Thongjuea, S., Woll, P. S., Azzoni, E., Giustacchini, A., Lutteropp, M., Bouriez-Jones, T., Vaidya, H., Mead, A. J., Atkinson, D., Böiers, C., Carrelha, J., MacAulay, I. C., Patient, R., Geissmann, F., Nerlov, C., Sandberg, R. & 4 andra, De Bruijn, M. F. T. R., Blackburn, C. C., Godin, I. & Jacobsen, S. E. W., 2016 dec 1, I : Nature Immunology. 17, 12, s. 1424-1435 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  71. Retinol dehydrogenase-10 regulates pancreas organogenesis and endocrine cell differentiation via paracrine retinoic acid signaling

    Arregi, I., Climent, M., Iliev, D., Strasser, J., Gouignard, N., Johansson, J. K., Tania Singh, Mazur, M., Semb, H., Isabella Artner, Minichiello, L. & Edgar M. Pera, 2016 dec 1, I : Endocrinology. 157, 12, s. 4615-4631 17 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  72. Direct Conversion of Fibroblasts to Megakaryocyte Progenitors

    Pulecio, J., Alejo-Valle, O., Sandra Capellera-Garcia, Vitaloni, M., Rio, P., Mejía-Ramírez, E., Caserta, I., Bueren, J. A., Johan Flygare & Raya, A., 2016 okt 11, I : Cell Reports. 17, 3, s. 671-683 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  73. Integrated Acoustic Separation, Enrichment, and Microchip Polymerase Chain Reaction Detection of Bacteria from Blood for Rapid Sepsis Diagnostics

    Pelle Ohlsson, Mikael Evander, Klara Petersson, Lisa Mellhammar, Lehmusvuori, A., Karhunen, U., Soikkeli, M., Seppä, T., Tuunainen, E., Spangar, A., Von Lode, P., Rantakokko-Jalava, K., Otto, G., Stefan Scheding, Soukka, T., Wittfooth, S. & Thomas Laurell, 2016 okt 4, I : Analytical Chemistry. 88, 19, s. 9403-9411 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  74. Improved minimal residual disease detection by targeted quantitative polymerase chain reaction in Nucleophosmin 1 type a mutated acute myeloid leukemia

    Louise Pettersson, Levéen, P., Axler, O., Dvorakova, D., Gunnar Juliusson & Mats Ehinger, 2016 okt 1, I : Genes, Chromosomes and Cancer. 55, 10, s. 750-766 17 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  75. Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML

    O Lindblad, Cordero, E., Puissant, A., Macaulay, L., Ramos, A., Kabir, N. N., J Sun, J Vallon-Christersson, Haraldsson, K., Hemann, M. T., Åke Borg, F Levander, Stegmaier, K., K Pietras, L Rönnstrand & J U Kazi, 2016 sep 29, I : Oncogene. 35, 39, s. 5119-5131 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  76. High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2

    Leefa, I., Prost, G., Williams, J. A., Moss, S. E. & Nuber, U. A., 2016 sep 16, I : Biochemical and Biophysical Research Communications. 478, 2, s. 573-579 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  77. α-Synuclein is a Novel Microtubule Dynamase

    Cartelli, D., Aliverti, A., Barbiroli, A., Santambrogio, C., Ragg, E. M., Casagrande, F. V. M., Cantele, F., Beltramone, S., Marangon, J., De Gregorio, C., Pandini, V., Emanuele, M., Chieregatti, E., Pieraccini, S., Holmqvist, S., Bubacco, L., Roybon, L., Pezzoli, G., Grandori, R., Arnal, I. & 1 andra, Cappelletti, G., 2016 sep 15, I : Scientific Reports. 6, 33289.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  78. The putative tumor suppressor gene EphA7 is a novel BMI-1 target

    Prost, G., Sebastian Braun, Hertwig, F., Winkler, M., Jagemann, L., Sara Nolbrant, Leefa, I. V., Offen, N., Kenichi Miharada, Stefan Lang, Isabella Artner & Nuber, U. A., 2016 sep 6, I : Oncotarget. 7, 36, s. 58203-58217 15 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  79. Autophagy dysfunction and regulatory cystatin C in macrophage death of atherosclerosis

    Li, W., Sultana, N., Siraj, N., Ward, L. J., Pawlik, M., Levy, E., Jovinge, S., Eva Bengtsson & Yuan, X. M., 2016 sep 1, I : Journal of Cellular and Molecular Medicine. 20, 9, s. 1664–1672 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  80. HESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation

    Andreas Heuer, Agnete Kirkeby, Pfisterer, U., Marie E. Jönsson & Malin Parmar, 2016 aug 1, I : Experimental Neurology. 282, s. 78-85 8 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  81. Src-like adaptor protein 2 (SLAP2) binds to and inhibits FLT3 signaling

    Sausan A Moharram, Chougule, R. A., Su, X., Li, T., Jianmin Sun, Zhao, H., Lars Rönnstrand & Julhash U Kazi, 2016 jul 21, I : Oncotarget. s. 1-13 13 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  82. An open-label phase I dose-finding study of APR-246 in hematological malignancies

    Deneberg, S., Cherif, H., Lazarevic, V. & G Juliusson, 2016 jul 16, I : Blood Cancer Journal. 6, 7, s. e447

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  83. MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC

    Sara Rolandsson Enes, Sjöland, A. A., Skog, I., Hansson, L., Larsson, H., Le Blanc, K., Leif Eriksson, Leif Bjermer, Stefan Scheding & Gunilla Westergren-Thorsson, 2016 jul 6, I : Scientific Reports. 6, 29160.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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