Anders Björklund

Seniorprofessor, ,
Fler filtreringsmöjligheter
  1. 2019
  2. Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease

    TRANSEURO consortium, Barker, R. A., Farrell, K., Guzman, N. V., He, X., Lazic, S. E., Moore, S., Morris, R., Tyers, P., Wijeyekoon, R., Daft, D., Hewitt, S., Dayal, V., Foltynie, T., Kefalopoulou, Z., Mahlknecht, P., Lao-Kaim, N. P., Piccini, P., Bjartmarz, H., Björklund, A. & 13 andraOlle Lindvall, Jenny Nelander-Wahlestedt, Malin Parmar, Gesine Paul, Hakan Widner, Church, A., Dunnett, S., Peall, K., Rosser, A., Gurruchaga, J. M., Palfi, S., Piroth, T. & Winkler, C., 2019 jul, I : Nature Medicine. 25, s. 1045–1053 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease

    Carl Rosenblad, Li, Q., Pioli, E. Y., Dovero, S., Antunes, A. S. L. M., Agúndez, L., Bardelli, M., Linden, R. M., Henckaerts, E., Anders Björklund, Bezard, E. & Tomas Björklund, 2019, I : Brain : a journal of neurology. s. 2402-2416

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. 2018
  5. Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease

    Faustini, G., Longhena, F., Varanita, T., Bubacco, L., Pizzi, M., Missale, C., Benfenati, F., Anders Björklund, Spano, P. F. & Bellucci, A., 2018 okt 1, I : Acta Neuropathologica. 136, 4, s. 621-639 19 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective

    Carta, M. & Anders Björklund, 2018 aug, I : Journal of Neural Transmission. 125, 8, s. 1195-1202

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. 2017
  8. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats

    Tronci, E., Napolitano, F., Muñoz, A., Fidalgo, C., Rossi, F., Anders Björklund, Usiello, A. & Carta, M., 2017 nov 1, I : Experimental Neurology. 297, s. 73-81 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain

    Thakur, P., Breger, L. S., Lundblad, M., Wan, O. W., Mattsson, B., Luk, K. C., Lee, V. M. Y., Trojanowski, J. Q. & Anders Björklund, 2017 sep 26, I : Proceedings of the National Academy of Sciences of the United States of America. 114, 39, s. E8284-E8293

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. Preface

    Dunnett, S. & A. Björklund, 2017 jan 1, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Vol. 230. s. xxv-xxvii (Progress in Brain Research).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingFör-/efterord

  11. Mechanisms and use of neural transplants for brain repair

    Dunnett, S. B. & A. Björklund, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Dunnett, S. B. & Björklund, A. (red.). Elsevier, Vol. 230. s. 1-51 (Progress in Brain Research; vol. 230).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  12. Preface

    Dunnett, S. B. & A. Björklund, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part B. Vol. 231. s. xxv-xxvii (Progress in Brain Research; vol. 231).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingFör-/efterord

  13. Replacing Dopamine Neurons in Parkinson's Disease: How did it happen?

    Anders Björklund & Olle Lindvall, 2017, I : Journal of Parkinson's Disease. 7, s1, s. S23-S33

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  14. 2016
  15. α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

    Wan, O. W., Shin, E., Mattsson, B., Caudal, D., Svenningsson, P. & Anders Björklund, 2016 maj 23, I : Scientific Reports. 6, 26285.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

    Barker, R. A., Malin Parmar, Agnete Kirkeby, Anders Björklund, Thompson, L. & Brundin, P., 2016, I : Journal of Parkinson's Disease. 6, 1, s. 57-63 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.

    Alvarsson, A., Caudal, D., Anders Björklund & Svenningsson, P., 2016, I : Behavioural Brain Research. 296, s. 129-133

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. 2015
  19. Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.

    Tamburrino, A., Churchill, M. J., Wan, O. W., Colino Sanguino, Y., Ippolito, R., Bergstrand, S., Wolf, D., Herz, N. J., Sconce, M. D., Anders Björklund, Meshul, C. K. & Decressac, M., 2015 dec 14, I : Acta neuropathologica communications. 3, 1, 84.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.

    Tozzi, A., de Iure, A., Bagetta, V., Tantucci, M., Durante, V., Quiroga-Varela, A., Costa, C., Di Filippo, M., Ghiglieri, V., Latagliata, E. C., Wegrzynowicz, M., Decressac, M., Giampà, C., Dalley, J. W., Xia, J., Gardoni, F., Mellone, M., El-Agnaf, O. M., Ardah, M. T., Puglisi-Allegra, S. & 4 andraAnders Björklund, Spillantini, M. G., Picconi, B. & Calabresi, P., 2015, I : Biological Psychiatry.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.

    Caudal, D., Alvarsson, A., Anders Björklund & Svenningsson, P., 2015, I : Experimental Neurology. 273, s. 243-252

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.

    Svenningsson, P., Carl Rosenblad, Af Edholm Arvidsson, K., Wictorin, K., Keywood, C., Shankar, B., Lowe, D. A., Anders Björklund & Håkan Widner, 2015, I : Brain. 138, Feb 10, s. 963-973

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. GDNF is not required for catecholaminergic neuron survival in vivo.

    Kopra, J., Vilenius, C., Shane Grealish, Härma, M-A., Varendi, K., Lindholm, J., Castrén, E., Võikar, V., Anders Björklund, Piepponen, T. P., Saarma, M. & Andressoo, J-O., 2015, I : Nature Neuroscience. 18, 3, s. 319-322

    Forskningsoutput: TidskriftsbidragLetter

  24. Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.

    Volakakis, N., Tiklova, K., Decressac, M., Papathanou, M., Mattsson, B., Gillberg, L., Nobre, A., Anders Björklund & Perlmann, T., 2015, I : Journal of Neuroscience. 35, 42, s. 14370-14385

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.

    Thompson, L. & Anders Björklund, 2015, I : Neurobiology of Disease. 79, Apr 22, s. 28-40

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  26. The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.

    Ruben Smith, Wu, K., Hart, T., Loane, C., Brooks, D. J., Anders Björklund, Per Odin, Piccini, P. & Politis, M., 2015, I : Neurobiology of Aging. 36, 4, s. 1736-1742

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.

    Bye, C. R., Marie Jönsson, Anders Björklund, Parish, C. L. & Thompson, L., 2015, I : Proceedings of the National Academy of Sciences. 112, 15, s. E1946-E1955

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. 2014
  29. Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports

    Kefalopoulou, Z., Politis, M., Piccini, P., Mencacci, N., Bhatia, K., Jahanshahi, M., Håkan Widner, Rehncrona, S., Brundin, P., Anders Björklund, Olle Lindvall, Limousin, P., Quinn, N. & Foltynie, T., 2014 jan, I : JAMA Neurology. 71, 1, s. 83-7 5 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.

    Shane Grealish, Diguet, E., Agnete Kirkeby, Mattsson, B., Andreas Heuer, Bramoulle, Y., Van Camp, N., Perrier, A. L., Hantraye, P., Anders Björklund & Malin Parmar, 2014, I : Cell Stem Cell. 15, 5, s. 653-665

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.

    Shin, E., Rogers, J. R., Devoto, P., Anders Björklund & Carta, M., 2014, I : Experimental Neurology. 257, Apr 18, s. 25-38

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.

    Shin, E., Lisci, C., Tronci, E., Fidalgo, C., Stancampiano, R., Anders Björklund & Carta, M., 2014, I : Neurobiology of Disease. 62, s. 233-240

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. 2013
  34. Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

    Bezard, E., Munoz, A., Tronci, E., Pioli, E. Y., Li, Q., Porras, G., Anders Björklund & Carta, M., 2013, I : Neuroscience Research. 77, 4, s. 242-246

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Cell therapy for Parkinson's disease: what next?

    Anders Björklund & Kordower, J. H., 2013, I : Movement Disorders. 28, 1, s. 110-115

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

    Barker, R., Barrett, J., Mason, S. L. & Anders Björklund, 2013, I : Lancet Neurology. 12, 1, s. 84-91

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  37. Generation of induced neurons via direct conversion in vivo.

    Torper, O., Pfisterer, U., Wolf, D., Pereira, M. J. M., Lau, S., Johan Jakobsson, Anders Björklund, Shane Grealish & Malin Parmar, 2013, I : Proceedings of the National Academy of Sciences. 110, 17, s. 7038-7043

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats

    Decressac, M. & Anders Björklund, 2013, I : Journal of Parkinson's Disease. 3, 1, s. 13-17

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  39. NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.

    Decressac, M., Volakakis, N., Anders Björklund & Perlmann, T., 2013, I : Nature Reviews Neurology. 9, 11, s. 629-636

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  40. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia

    Bezard, E., Tronci, E., Pioli, E. Y., Li, Q., Porras, G., Anders Björklund & Carta, M., 2013, I : Movement Disorders. 28, 8, s. 1088-1096

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.

    Decressac, M., Mattsson, B., Weikop, P., Lundblad, M., Johan Jakobsson & Anders Björklund, 2013, I : Proceedings of the National Academy of Sciences. 110, 19, s. E1817-E1826

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. TFEB: Pathogenic role and therapeutic target in Parkinson disease.

    Decressac, M. & Anders Björklund, 2013, I : Autophagy. 9, 8, s. 1244-1246

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

    Kadkhodaei, B., Alvarsson, A., Schintu, N., Ramskold, D., Volakakis, N., Joodmardi, E., Yoshitake, T., Kehr, J., Decressac, M., Anders Björklund, Sandberg, R., Svenningsson, P. & Perlmann, T., 2013, I : Proceedings of the National Academy of Sciences. 110, 6, s. 2360-2365

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. Trophic Factor Gene Therapy for Parkinson's Disease

    Kordower, J. H. & Anders Björklund, 2013, I : Movement Disorders. 28, 1, s. 96-109

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  45. 2012
  46. Profile of Anders Bjorklund. Interview by Beth Azar

    Anders Björklund, 2012 aug 14, I : Proceedings of the National Academy of Sciences of the United States of America. 109, 33, s. 13137-9 3 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. Alpha-Synuclein Cell-to-Cell Transfer and Seeding in Grafted Dopaminergic Neurons In Vivo.

    Angot, E., Steiner, J., Lema Tomé, C., Ekström, P., Mattsson, B., Anders Björklund & Brundin, P., 2012, I : PLoS ONE. 7, 6, e39465.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. Amphetamine-induced rotation and l-DOPA-induced dyskinesia in the rat 6-OHDA model: A correlation study.

    Tronci, E., Shin, E., Anders Björklund & Carta, M., 2012, I : Neuroscience Research. 73, 2, s. 168-172

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. Comparison of the behavioural and histological characteristics of the 6-OHDA and alpha-synuclein rat models of Parkinson's disease

    Decressac, M., Mattsson, B. & Anders Björklund, 2012, I : Experimental Neurology. 235, 1, s. 306-315

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  50. Generation of Transplantable Striatal Projection Neurons from Human ESCs.

    Malin Parmar & Anders Björklund, 2012, I : Cell Stem Cell. 10, 4, s. 349-350

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. Impaired neurotransmission caused by overexpression of α-synuclein in nigral dopamine neurons.

    Lundblad, M., Decressac, M., Mattsson, B. & Anders Björklund, 2012, I : Proceedings of the National Academy of Sciences. 109, 9, s. 3213-3219

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. Introduction (Part I)

    Dunnett, S. B. & Anders Björklund, 2012, Functional Neural Transplantation III : Primary and stem cell therapies for brain repair. Part 1 . Dunnett, S. B. & Björklund, A. (red.). Elsevier, Vol. 200. s. 3-5 3 s. (Progress in Brain Research).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  53. Introduction (Part II)

    Dunnett, S. B. & Anders Björklund, 2012, Functional Neural Transplantation III: Primary and Stem Cell Therapies for Brain Repair, Part II. Dunnett, S. B. & Björklund, A. (red.). Elsevier, Vol. 201. s. 3-5 3 s. (Progress in brain research).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  54. Progressive neurodegenerative and behavioural changes induced by AAV-mediated overexpression of α-synuclein in midbrain dopamine neurons.

    Decressac, M., Mattsson, B., Lundblad, M., Weikop, P. & Anders Björklund, 2012, I : Neurobiology of Disease. 45, 3, s. 939-953

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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