Anders Björklund

Seniorprofessor, ,
Fler filtreringsmöjligheter
  1. 2021
  2. 2020
  3. Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD

    Deirdre B Hoban, Shelby Shrigley, Bengt Mattsson, Ludivine S Breger, Ulla Jarl, Tiago Cardoso, Jenny Nelander Wahlestedt, Kelvin C Luk, Anders Björklund & Malin Parmar, 2020 jun 30, I: Proceedings of the National Academy of Sciences of the United States of America. 117, 26, s. 15209-15220

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. Transsynaptic tracing and its emerging use to assess graftreconstructed neural circuits

    Andrew Adler, Anders Björklund & Malin Parmar, 2020 jun, I: Stem Cells. 38, 6, s. 716-726 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. Preface: The evolving scenario of Parkinson's research

    Anders Björklund & M. Angela Cenci, 2020 apr 1, Recent Advances in Parkinson's Disease. Björklund, A. & Cenci, M. A. (red.). 1 uppl. Elsevier Science Publishers B.V., s. xix-xx 2 s. (Progress in Brain Research; vol. 252).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingFör-/efterord

  6. Parkinson’s disease laterality: a 11C-PE2I PET imaging study

    Roger A. Barker, Hjalmar Bjartmarz, Anders Björklund, Christian Winkler & TRANSEURO consortium TRANSEURO consortium, 2020 jan, I: Journal of Neurology.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  7. Animal models for preclinical Parkinson´s research: An update and critical appraisal

    Angela Cenci Nilsson & Anders Björklund, 2020, Recent Advances in Parkinson's Disease. Elsevier, Vol. 252. s. 27-59 (Progress in Brain Research; vol. 252).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  8. Animal Models of Parkinson's Disease: Are They Useful or Not?

    Roger A Barker & Anders Björklund, 2020, I: Journal of Parkinson's Disease. 10, 4, s. 1335-1342 8 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  9. BDNF Overexpression Increases Striatal D3 Receptor Level at Striatal Neurons and Exacerbates D1-Receptor Agonist-Induced Dyskinesia

    Simona Scheggi, Francesca Rossi, Sara Corsi, Silvia Fanni, Elisabetta Tronci, Congiu Ludovica, Romina Vargiu, Carla Gambarana, Ana Muñoz, Roberto Stancampiano, Anders Björklund & Manolo Carta, 2020, I: Journal of Parkinson's Disease. 10, 4, s. 1503-1514 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  10. From Skin to Brain: A Parkinson's Disease Patient Transplanted with His Own Cells

    Malin Parmar & Anders Björklund, 2020, I: Cell Stem Cell. 27, 1, s. 8-10 3 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. GDNF and Parkinson's Disease: Where Next? A Summary from a Recent Workshop

    Roger A. Barker, Anders Björklund, Don M. Gash, Alan Whone, Amber Van Laar, Jeffrey H. Kordower, Krystof Bankiewicz, Karl Kieburtz, Mart Saarma, Sigrid Booms, Henri J. Huttunen, Adrian P. Kells, Massimo S. Fiandaca, A. Jon Stoessl, David Eidelberg, Howard Federoff, Merja H. Voutilainen, David T. Dexter, Jamie Eberling, Patrik Brundin & 11 andra, Lyndsey Isaacs, Leah Mursaleen, Eros Bresolin, Camille Carroll, Alasdair Coles, Brian Fiske, Helen Matthews, Codrin Lungu, Richard K. Wyse, Simon Stott & Anthony E. Lang, 2020, I: Journal of Parkinson's Disease. 10, 3, s. 875-891 17 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. 2019
  13. hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson's Disease

    Andrew F. Adler, Tiago Cardoso, Sara Nolbrant, Bengt Mattsson, Deirdre B. Hoban, Ulla Jarl, Jenny Nelander Wahlestedt, Shane Grealish, Anders Björklund & Malin Parmar, 2019 sep 24, I: Cell Reports. 28, 13, s. 3462-3473.e5

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  14. Designing stem-cell-based dopamine cell replacement trials for Parkinson’s disease

    Roger A. Barker, Krista Farrell, Natalie Valle Guzman, Xiaoling He, Stanley E. Lazic, Sarah Moore, Robert Morris, Pamela Tyers, Ruwani Wijeyekoon, Danielle Daft, Sam Hewitt, Viswas Dayal, Thomas Foltynie, Zinovia Kefalopoulou, Philipp Mahlknecht, Nick P. Lao-Kaim, Paola Piccini, Hjalmar Bjartmarz, Anders Björklund, Olle Lindvall & 13 andra, Jenny Nelander-Wahlestedt, Malin Parmar, Gesine Paul, Hakan Widner, Alistair Church, Stephen Dunnett, Kathryn Peall, Anne Rosser, Jean Marc Gurruchaga, Stéphane Palfi, Tobias Piroth, Christian Winkler & TRANSEURO consortium TRANSEURO consortium, 2019 jul, I: Nature Medicine. 25, s. 1045–1053 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. Vector-mediated l-3,4-dihydroxyphenylalanine delivery reverses motor impairments in a primate model of Parkinson's disease

    Carl Rosenblad, Qin Li, Elsa Y Pioli, Sandra Dovero, André S L M Antunes, Leticia Agúndez, Martino Bardelli, R Michael Linden, Els Henckaerts, Anders Björklund, Erwan Bezard & Tomas Björklund, 2019, I: Brain : a journal of neurology. s. 2402-2416

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. 2018
  17. Synapsin III deficiency hampers α-synuclein aggregation, striatal synaptic damage and nigral cell loss in an AAV-based mouse model of Parkinson’s disease

    Gaia Faustini, Francesca Longhena, Tatiana Varanita, Luigi Bubacco, Marina Pizzi, Cristina Missale, Fabio Benfenati, Anders Björklund, Pier Franco Spano & Arianna Bellucci, 2018 okt 1, I: Acta Neuropathologica. 136, 4, s. 621-639 19 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  18. The serotonergic system in L-DOPA-induced dyskinesia: pre-clinical evidence and clinical perspective

    Manolo Carta & Anders Björklund, 2018 aug, I: Journal of Neural Transmission. 125, 8, s. 1195-1202

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

    Tiago Cardoso, Andrew F. Adler, Bengt Mattsson, Deirdre B. Hoban, Sara Nolbrant, Jenny Nelander Wahlestedt, Agnete Kirkeby, Shane Grealish, Anders Björklund & Malin Parmar, 2018, I: Journal of Comparative Neurology. 526, 13, s. 2133-2146

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  20. 2017
  21. BDNF over-expression induces striatal serotonin fiber sprouting and increases the susceptibility to L-DOPA-induced dyskinesia in 6-OHDA-lesioned rats

    Elisabetta Tronci, Francesco Napolitano, Ana Muñoz, Camino Fidalgo, Francesca Rossi, Anders Björklund, Alessandro Usiello & Manolo Carta, 2017 nov 1, I: Experimental Neurology. 297, s. 73-81 9 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Modeling Parkinson’s disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain

    Poonam Thakur, Ludivine S. Breger, Martin Lundblad, Oi Wan Wan, Bengt Mattsson, Kelvin C. Luk, Virginia Man Yee Lee, John Q Trojanowski & Anders Björklund, 2017 sep 26, I: Proceedings of the National Academy of Sciences of the United States of America. 114, 39, s. E8284-E8293

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. Preface

    S. Dunnett & A. Björklund, 2017 jan 1, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Vol. 230. s. xxv-xxvii (Progress in Brain Research).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingFör-/efterord

  24. Mechanisms and use of neural transplants for brain repair

    S. B Dunnett & A. Björklund, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part A. Dunnett, S. B. & Björklund, A. (red.). Elsevier, Vol. 230. s. 1-51 (Progress in Brain Research; vol. 230).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  25. Preface

    S. B Dunnett & A. Björklund, 2017, Functional Neural Transplantation IV Translation to Clinical Application, Part B. Vol. 231. s. xxv-xxvii (Progress in Brain Research; vol. 231).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingFör-/efterord

  26. Replacing Dopamine Neurons in Parkinson's Disease: How did it happen?

    Anders Björklund & Olle Lindvall, 2017, I: Journal of Parkinson's Disease. 7, s1, s. S23-S33

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  27. 2016
  28. α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

    Oi Wan Wan, Eunju Shin, Bengt Mattsson, Dorian Caudal, Per Svenningsson & Anders Björklund, 2016 maj 23, I: Scientific Reports. 6, 26285.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  29. Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

    Roger A Barker, Malin Parmar, Agnete Kirkeby, Anders Björklund, Lachlan Thompson & Patrik Brundin, 2016, I: Journal of Parkinson's Disease. 6, 1, s. 57-63 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area.

    A Alvarsson, D Caudal, Anders Björklund & P Svenningsson, 2016, I: Behavioural Brain Research. 296, s. 129-133

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. 2015
  32. Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.

    Anna Tamburrino, Madeline J Churchill, Oi Wan Wan, Yolanda Colino Sanguino, Rossana Ippolito, Sofie Bergstrand, Daniel Wolf, Niculin J Herz, Michelle D Sconce, Anders Björklund, Charles K Meshul & Mickael Decressac, 2015 dec 14, I: Acta Neuropathologica Communications. 3, 1, 84.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.

    Alessandro Tozzi, Antonio de Iure, Vincenza Bagetta, Michela Tantucci, Valentina Durante, Ana Quiroga-Varela, Cinzia Costa, Massimiliano Di Filippo, Veronica Ghiglieri, Emanuele Claudio Latagliata, Michal Wegrzynowicz, Mickael Decressac, Carmela Giampà, Jeffrey W Dalley, Jing Xia, Fabrizio Gardoni, Manuela Mellone, Omar Mukhtar El-Agnaf, Mustafa Taleb Ardah, Stefano Puglisi-Allegra & 4 andra, Anders Björklund, Maria Grazia Spillantini, Barbara Picconi & Paolo Calabresi, 2015, I: Biological Psychiatry.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons.

    D Caudal, A Alvarsson, Anders Björklund & P Svenningsson, 2015, I: Experimental Neurology. 273, s. 243-252

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.

    Per Svenningsson, Carl Rosenblad, Karolina Af Edholm Arvidsson, Klas Wictorin, Charlotte Keywood, Bavani Shankar, David A Lowe, Anders Björklund & Håkan Widner, 2015, I: Brain. 138, Feb 10, s. 963-973

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. GDNF is not required for catecholaminergic neuron survival in vivo.

    Jaakko Kopra, Carolina Vilenius, Shane Grealish, Mari-Anne Härma, Kärt Varendi, Jesse Lindholm, Eero Castrén, Vootele Võikar, Anders Björklund, T Petteri Piepponen, Mart Saarma & Jaan-Olle Andressoo, 2015, I: Nature Neuroscience. 18, 3, s. 319-322

    Forskningsoutput: TidskriftsbidragLetter

  37. Nurr1 and Retinoid X Receptor Ligands Stimulate Ret Signaling in Dopamine Neurons and Can Alleviate α-Synuclein Disrupted Gene Expression.

    Nikolaos Volakakis, Katarina Tiklova, Mickael Decressac, Maria Papathanou, Bengt Mattsson, Linda Gillberg, André Nobre, Anders Björklund & Thomas Perlmann, 2015, I: Journal of Neuroscience. 35, 42, s. 14370-14385

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. Reconstruction of brain circuitry by neural transplants generated from pluripotent stem cells.

    Lachlan Thompson & Anders Björklund, 2015, I: Neurobiology of Disease. 79, Apr 22, s. 28-40

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  39. The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study.

    Ruben Smith, Kit Wu, Thomas Hart, Clare Loane, David J Brooks, Anders Björklund, Per Odin, Paola Piccini & Marios Politis, 2015, I: Neurobiology of Aging. 36, 4, s. 1736-1742

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  40. Transcriptome analysis reveals transmembrane targets on transplantable midbrain dopamine progenitors.

    Chris R Bye, Marie Jönsson, Anders Björklund, Clare L Parish & Lachlan Thompson, 2015, I: Proceedings of the National Academy of Sciences. 112, 15, s. E1946-E1955

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. 2014
  42. Long-term clinical outcome of fetal cell transplantation for Parkinson disease: two case reports

    Zinovia Kefalopoulou, Marios Politis, Paola Piccini, Niccolo Mencacci, Kailash Bhatia, Marjan Jahanshahi, Håkan Widner, Stig Rehncrona, Patrik Brundin, Anders Björklund, Olle Lindvall, Patricia Limousin, Niall Quinn & Thomas Foltynie, 2014 jan, I: JAMA Neurology. 71, 1, s. 83-7 5 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson's Disease.

    Shane Grealish, Elsa Diguet, Agnete Kirkeby, Bengt Mattsson, Andreas Heuer, Yann Bramoulle, Nadja Van Camp, Anselme L Perrier, Philippe Hantraye, Anders Björklund & Malin Parmar, 2014, I: Cell Stem Cell. 15, 5, s. 653-665

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. Noradrenaline neuron degeneration contributes to motor impairments and development of L-DOPA-induced dyskinesia in a rat model of Parkinson's disease.

    Eunju Shin, James R Rogers, Paola Devoto, Anders Björklund & Manolo Carta, 2014, I: Experimental Neurology. 257, Apr 18, s. 25-38

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  45. The anti-dyskinetic effect of dopamine receptor blockade is enhanced in parkinsonian rats following dopamine neuron transplantation.

    Eunju Shin, Carlo Lisci, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Anders Björklund & Manolo Carta, 2014, I: Neurobiology of Disease. 62, s. 233-240

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. 2013
  47. Anti-dyskinetic effect of anpirtoline in animal models of L-DOPA-induced dyskinesia

    Erwan Bezard, Ana Munoz, Elisabetta Tronci, Elsa Y. Pioli, Qin Li, Gregory Porras, Anders Björklund & Manolo Carta, 2013, I: Neuroscience Research. 77, 4, s. 242-246

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. Cell therapy for Parkinson's disease: what next?

    Anders Björklund & Jeffrey H Kordower, 2013, I: Movement Disorders. 28, 1, s. 110-115

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

    Roger Barker, Jessica Barrett, Sarah L. Mason & Anders Björklund, 2013, I: Lancet Neurology. 12, 1, s. 84-91

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  50. Generation of induced neurons via direct conversion in vivo.

    Olof Torper, Ulrich Pfisterer, Daniel Wolf, Maria J M Pereira, Shong Lau, Johan Jakobsson, Anders Björklund, Shane Grealish & Malin Parmar, 2013, I: Proceedings of the National Academy of Sciences. 110, 17, s. 7038-7043

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. mTOR Inhibition Alleviates L-DOPA-Induced Dyskinesia in Parkinsonian Rats

    Mickael Decressac & Anders Björklund, 2013, I: Journal of Parkinson's Disease. 3, 1, s. 13-17

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.

    Mickael Decressac, Nikolaos Volakakis, Anders Björklund & Thomas Perlmann, 2013, I: Nature Reviews Neurology. 9, 11, s. 629-636

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  53. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia

    Erwan Bezard, Elisabetta Tronci, Elsa Y. Pioli, Qin Li, Gregory Porras, Anders Björklund & Manolo Carta, 2013, I: Movement Disorders. 28, 8, s. 1088-1096

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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