Johan Jakobsson

Professor, , , , , ,
Fler filtreringsmöjligheter
  1. 2019
  2. Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

    Marie E. Jönsson, Ludvik Brattås, P., Gustafsson, C., Petri, R., David Yudovich, Karolina Pircs, Verschuere, S., Madsen, S., Jenny Hansson, Jonas Larsson, Månsson, R., Meissner, A. & Johan Jakobsson, 2019 jul 18, I : Nature Communications. 10, 1, 3182.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. Driving Neuronal Differentiation through Reversal of an ERK1/2-miR-124-SOX9 Axis Abrogates Glioblastoma Aggressiveness

    Sabelström, H., Petri, R., Shchors, K., Jandial, R., Schmidt, C., Sacheva, R., Masic, S., Yuan, E., Fenster, T., Martinez, M., Saxena, S., Nicolaides, T. P., Ilkhanizadeh, S., Berger, M. S., Snyder, E. Y., Weiss, W. A., J. Jakobsson & Persson, A. I., 2019, I : Cell Reports. 28, 8, s. 2064-2079.e11

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  4. LINE-2 transposable elements are a source of functional human microRNAs and target sites

    Petri, R., Brattås, P. L., Sharma, Y., Marie E. Jönsson, Karolina Pircs, Johan Bengzon & Johan Jakobsson, 2019, I : PLoS Genetics. 15, 3, s. e1008036

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. TRIM28 and the control of transposable elements in the brain

    Daniela A. Grassi, Marie E. Jönsson, Brattås, P. L. & Johan Jakobsson, 2019, I : Brain Research. 1705, s. 43-47 5 s.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  6. 2018
  7. Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis

    Kutsche, L. K., Gysi, D. M., Fallmann, J., Lenk, K., Petri, R., Swiersy, A., Klapper, S. D., Karolina Pircs, Khattak, S., Stadler, P. F., Johan Jakobsson, Nowick, K. & Busskamp, V., 2018 okt, I : Cell systems. 7, 4, s. 438-452 15 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

    Karolina Pircs, Petri, R., Madsen, S., Brattås, P. L., Vuono, R., Daniella R. Ottosson, St-Amour, I., Hersbach, B. A., Matusiak-Brückner, M., Lundh, S. H., Åsa Petersén, Déglon, N., Hébert, S. S., Malin Parmar, Barker, R. A. & Johan Jakobsson, 2018 aug, I : Cell Reports. 24, 6, s. 1397-1406 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. Identifying miRNA targets using AGO-RIPseq

    Petri, R. & Johan Jakobsson, 2018, Methods in Molecular Biology. Humana Press, Vol. 1720. s. 131-140 10 s. (Methods in Molecular Biology; vol. 1720).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  10. In vivo electrochemical studies of optogenetic control of glutamate signaling measured using enzyme-based ceramic microelectrode arrays

    Burmeister, J. J., Pomerleau, F., Quintero, J. E., Huettl, P., Ai, Y., Johan Jakobsson, Lundblad, M., Andreas Heuer, Slevin, J. T. & Gerhardt, G. A., 2018, Neuromethods. Humana Press, Vol. 130. s. 327-351 25 s. (Neuromethods; vol. 130).

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  11. 2017
  12. A new approach for ratiometric in vivo calcium imaging of microglia

    Brawek, B., Liang, Y., Savitska, D., Li, K., Fomin-Thunemann, N., Kovalchuk, Y., Zirdum, E., Johan Jakobsson & Garaschuk, O., 2017 dec 1, I : Scientific Reports. 7, 1, 6030.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. Direct neuronal reprogramming for disease modeling studies using patient-derived neurons: What have we learned?

    Drouin-Ouellet, J., Karolina Pircs, Barker, R. A., Johan Jakobsson & Malin Parmar, 2017 sep 28, I : Frontiers in Neuroscience. 11, SEP, 530.

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  14. TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells

    Brattås, P. L., Marie E. Jönsson, Fasching, L., Jenny Nelander Wahlestedt, Shahsavani, M., Falk, R., Falk, A. H., Jern, P., Malin Parmar & Johan Jakobsson, 2017 jan 3, I : Cell Reports. 18, 1, s. 1-11 11 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. let-7 regulates radial migration of new-born neurons through positive regulation of autophagy

    Petri, R., Karolina Pircs, Marie E Jönsson, Malin Åkerblom, Brattås, P. L., Klussendorf, T. & Johan Jakobsson, 2017, I : EMBO Journal. 36, s. 1379-1391

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways

    Drouin-Ouellet, J., Lau, S., Brattås, P. L., Daniella Ottosson, Karolina Pircs, Daniela A Grassi, Collins, L. M., Vuono, R., Andersson Sjöland, A., Gunilla Westergren-Thorsson, Graff, C., Lennart Minthon, Håkan Toresson, Barker, R. A., Johan Jakobsson & Malin Parmar, 2017, I : EMBO Molecular Medicine. 9, 8, s. 1117-1131

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  17. 2016
  18. Distinct cognitive effects and underlying transcriptome changes upon inhibition of individual miRNAs in hippocampal neurons.

    Malmevik, J., Petri, R., Knauff, P., Brattaas, P. L., Malin Åkerblom & Johan Jakobsson, 2016, I : Scientific Reports. 6, 19879.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. 2015
  20. Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice

    Fritz, M., Klawonn, A. M., Nilsson, A., Singh, A. K., Zajdel, J., Björk Wilhelms, D., Lazarus, M., Löfberg, A., Jaarola, M., Örtegren Kugelberg, U., Billiar, T. R., Hackam, D. J., Sodhi, C. P., Breyer, M. D., Jakobsson, J., Schwaninger, M., Schütz, G., Rodriguez Parkitna, J., Saper, C. B., Blomqvist, A. & 1 andraEngblom, D., 2015 dec 21, I : Journal of Clinical Investigation. 126, 2, s. 695-705

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  21. Identification of the miRNA targetome in hippocampal neurons using RIP-seq.

    Malmevik, J., Petri, R., Klüssendorf, T., Knauff, P., Malin Åkerblom, Jenny G Johansson, Shamit Soneji & Johan Jakobsson, 2015, I : Scientific Reports. 5, 12609.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. TRIM28 Represses Transcription of Endogenous Retroviruses in Neural Progenitor Cells.

    Fasching, L., Kapopoulou, A., Sachdeva, R., Petri, R., Marie Jönsson, Männe, C., Turelli, P., Jern, P., Cammas, F., Trono, D. & Johan Jakobsson, 2015, I : Cell Reports. 10, 1, s. 20-28

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. 2014
  24. Cell therapies for Parkinson's disease

    Malin Parmar, Kristina Hug, Bjartmarz, H., Johan Jakobsson, Göran Hermerén & Gesine Paul-Visse, 2014, I : Advances in Clinical Neuroscience and Rehabilitation. 14, 3, s. 26-28

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. Direct neural conversion from human fibroblasts using self-regulating and nonintegrating viral vectors.

    Lau, S., Daniella Rylander, Johan Jakobsson & Malin Parmar, 2014, I : Cell Reports. 9, 5, s. 1673-1680

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons.

    Malin Åkerblom, Petri, R., Sachdeva, R., Klüssendorf, T., Mattsson, B., Gentner, B. & Johan Jakobsson, 2014, I : Development. 141, 7, s. 1580-1588

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  27. MicroRNAs as Neuronal Fate Determinants.

    Malin Åkerblom & Johan Jakobsson, 2014, I : Neuroscientist. 20, 3, s. 235-242

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  28. miRNAs in brain development.

    Petri, R., Malmevik, J., Fasching, L., Malin Åkerblom & Johan Jakobsson, 2014, I : Experimental Cell Research. 321, 1, s. 84-89

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  29. 2013
  30. microRNA and Neurodegenerative Diseases

    Malmevik, J., Malin Åkerblom & Johan Jakobsson, 2013 okt, microRNAs in Toxicology and Medicine. Sahu, S. C. (red.). Wiley-Blackwell

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  31. Generation of induced neurons via direct conversion in vivo.

    Torper, O., Pfisterer, U., Wolf, D., Pereira, M. J. M., Lau, S., Johan Jakobsson, Anders Björklund, Shane Grealish & Malin Parmar, 2013, I : Proceedings of the National Academy of Sciences. 110, 17, s. 7038-7043

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity.

    Decressac, M., Mattsson, B., Weikop, P., Lundblad, M., Johan Jakobsson & Anders Björklund, 2013, I : Proceedings of the National Academy of Sciences. 110, 19, s. E1817-E1826

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  33. TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells

    Rowe, H. M., Kapopoulou, A., Corsinotti, A., Fasching, L., Macfarlan, T. S., Tarabay, Y., Viville, S., Johan Jakobsson, Pfaff, S. L. & Trono, D., 2013, I : Genome Research. 23, 3, s. 452-461

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Visualization and genetic modification of resident brain microglia using lentiviral vectors regulated by microRNA-9.

    Malin Åkerblom, Sachdeva, R., Luis Quintino, Wettergren, E. E., Chapman, K., Manfre, G., Olle Lindvall, Cecilia Lundberg & Johan Jakobsson, 2013, I : Nature Communications. 4, 1770.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. 2012
  36. Functional Studies of microRNAs in Neural Stem Cells: Problems and Perspectives

    Malin Åkerblom, Sachdeva, R. & Johan Jakobsson, 2012, I : Frontiers in Neuroscience. 6, s. 14 14.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. MicroRNA-124 Is a Subventricular Zone Neuronal Fate Determinant.

    Malin Åkerblom, Sachdeva, R., Barde, I., Verp, S., Gentner, B., Trono, D. & Johan Jakobsson, 2012, I : The Journal of neuroscience : the official journal of the Society for Neuroscience. 32, 26, s. 8879-8889

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. 2011
  39. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions

    Quenneville, S., Verde, G., Corsinotti, A., Kapopoulou, A., Johan Jakobsson, Offner, S., Baglivo, I., Pedone, P. V., Grimaldi, G., Riccio, A. & Trono, D., 2011 nov 4, I : Molecular Cell. 44, 3, s. 361-72 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  40. Using Endogenous MicroRNA Expression Patterns to Visualize Neural Differentiation of Human Pluripotent Stem Cells

    Agnete Kirkeby, Malin Parmar & Johan Jakobsson, 2011 jul 30, Human Embryonic and Induced Pluripotent Stem Cells: Part of the series Springer Protocols Handbooks . Ye, K. & Jin, S. (red.). Springer, s. 465-480

    Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKapitel samlingsverk

  41. Direct conversion of human fibroblasts to dopaminergic neurons.

    Pfisterer, U., Agnete Kirkeby, Torper, O., Wood, J., Jenny Nelander Wahlestedt, Dufour, A., Anders Björklund, Olle Lindvall, Johan Jakobsson & Malin Parmar, 2011, I : Proceedings of the National Academy of Sciences. 108, 25, s. 10343-10348

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. Lineage reprogramming: A shortcut to generating functional neurons from fibroblasts.

    Shane Grealish, Johan Jakobsson & Malin Parmar, 2011, I : Cell Cycle. 10, 20, s. 3421-3422

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Turning skin into dopamine neurons.

    Malin Parmar & Johan Jakobsson, 2011, I : Cell Research. 21, s. 1386-1387

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. 2010
  45. KAP1 controls endogenous retroviruses in embryonic stem cells

    Rowe, H. M., Johan Jakobsson, Mesnard, D., Rougemont, J., Reynard, S., Aktas, T., Maillard, P. V., Layard-Liesching, H., Verp, S., Marquis, J., Spitz, F., Constam, D. B. & Trono, D., 2010 jan 14, I : Nature. 463, s. 237-40

    Forskningsoutput: TidskriftsbidragLetter

  46. Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.

    Sachdeva, R., Marie Jönsson, Jenny Nelander Wahlestedt, Agnete Kirkeby, Guibentif, C., Gentner, B., Naldini, L., Anders Björklund, Malin Parmar & Johan Jakobsson, 2010, I : Proceedings of the National Academy of Sciences. 107, 25, s. 11602-11607

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  47. 2009
  48. Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants

    Nielsen, T. T., Johan Jakobsson, Rosenqvist, N. & Cecilia Lundberg, 2009, I : BMC Biotechnology. 9

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. 2008
  50. KAP1-Mediated Epigenetic Repression in the Forebrain Modulates Behavioral Vulnerability to Stress

    Johan Jakobsson, Cordero, M. I., Bisaz, R., Groner, A. C., Busskamp, V., Bensadoun, J-C., Cammas, F., Losson, R., Mansuy, I. M., Sandi, C. & Trono, D., 2008 dec 10, I : Neuron. 60, 5, s. 818-831

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. Applications of lentiviral vectors for biology and gene therapy of neurological disorders.

    Cecilia Lundberg, Tomas Björklund, Carlsson, T., Johan Jakobsson, Hantraye, P., Déglon, N. & Deniz Kirik, 2008, I : Current Gene Therapy. 8, 6, s. 461-473

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. 2007
  53. The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis

    Wiznerowicz, M., Johan Jakobsson, Szulc, J., Liao, S., Quazzola, A., Beermann, F., Aebischer, P. & Trono, D., 2007 nov 23, I : Journal of Biological Chemistry. 282, 47, s. 34535-41 7 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  54. 2006
  55. Efficient transduction of neurons using Ross River glycoprotein-pseudotyped lentiviral vectors.

    Johan Jakobsson, Tolstrup Nielsen, T., Staflin, K., Georgievska, B. & Cecilia Lundberg, 2006, I : Gene Therapy. 13, 12, s. 966-973

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  56. Evidence for disease-regulated transgene expression in the brain with use of lentiviral vectors.

    Johan Jakobsson, Rosenqvist, N., Marild, K., V Agoston, D. & Cecilia Lundberg, 2006, I : Journal of Neuroscience Research. 84, 1, s. 58-67

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  57. Lentiviral Vectors for Use in the Central Nervous System.

    Johan Jakobsson & Cecilia Lundberg, 2006, I : Molecular Therapy. 13, 3, s. 484-493

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  58. 2005
  59. Development of lentiviral vectors for CNS gene transfer

    Johan Jakobsson, 2005, Johan Jakobsson. 134 s.

    Forskningsoutput: AvhandlingDoktorsavhandling (sammanläggning)

  60. Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain.

    Rosenqvist, N., Johan Jakobsson & Cecilia Lundberg, 2005, I : Cell Transplantation. 14, 2-3, s. 129-138

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  61. 2004
  62. Dynamics of transgene expression in a neural stem cell line transduced with lentiviral vectors incorporating the cHS4 insulator.

    Johan Jakobsson, Rosenqvist, N., Thompson, L., Barraud, P. & Cecilia Lundberg, 2004, I : Experimental Cell Research. 298, 2, s. 611-623

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  63. Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector.

    Johan Jakobsson, Georgievska, B., Ericson, C. & Cecilia Lundberg, 2004, I : European Journal of Neuroscience. 19, 3, s. 761-765

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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