Mikael Sigvardsson

Professor, Kallad
Fler filtreringsmöjligheter
  1. 2020
  2. 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

    Minjun Yang, Setareh Safavi, Eleanor L Woodward, Nicolas Duployez, Linda Olsson-arvidsson, Jonas Ungerbäck, Mikael Sigvardsson, Marketa Zaliova, Jan Zuna, Thoas Fioretos, Bertil Johansson, Karolin H Nord & Kajsa Paulsson, 2020 maj 8, I : Blood.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  3. Progression of progenitor B-cell leukemia is associated with alterations of the bone marrow micro-environment

    Josefine Åhsberg, Pingnan Xiao, Kazuki Okuyama, Rajesh Somasundaram, Tobias Strid, Hong Qian & Mikael Sigvardsson, 2020 mar, I : Haematologica. 105, 3, s. E102-E106 5 s.

    Forskningsoutput: TidskriftsbidragLetter

  4. ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development

    Audrey Astori, Johanna Tingvall-Gustafsson, Jacob Kuruvilla, Etienne Coyaud, Estelle M.N. Laurent, Maria Sunnerhagen, Josefine Åhsberg, Jonas Ungerbäck, Tobias Strid, Mikael Sigvardsson, Brian Raught & Rajesh Somasundaram, 2020, I : Journal of immunology (Baltimore, Md. : 1950). 205, 5, s. 1419-1432 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  5. Ezh2 Represses Transcription of Innate Lymphoid Genes in B Lymphocyte Progenitors and Maintains the B-2 Cell Fate

    Jennifer A. Jacobsen, Elizabeth T. Bartom, Mikael Sigvardsson & Barbara L. Kee, 2020, I : Journal of immunology (Baltimore, Md. : 1950). 204, 7, s. 1760-1769 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  6. 2019
  7. PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

    Kazuki Okuyama, Tobias Strid, Jacob Kuruvilla, Rajesh Somasundaram, Susana Cristobal, Emma Smith, Mahadesh Prasad, Thoas Fioretos, Henrik Lilljebjörn, Shamit Soneji, Stefan Lang, Jonas Ungerbäck & Mikael Sigvardsson, 2019 aug 1, I : PLoS Genetics. 15, 8, e1008280.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  8. Cutting Edge: Lymphomyeloid-Primed Progenitor Cell Fates Are Controlled by the Transcription Factor Tal1

    Renée F. de Pooter, Sheila Dias, Munmun Chowdhury, Elisabeth T. Bartom, Michael K. Okoreeh, Mikael Sigvardsson & Barbara L. Kee, 2019, I : Journal of immunology (Baltimore, Md. : 1950). 202, 10, s. 2837-2842 6 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  9. 2018
  10. Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis

    Christina T Jensen, Josefine Åhsberg, Mikael N E Sommarin, Tobias Strid, Rajesh Somasundaram, Kazuki Okuyama, Jonas Ungerbäck, Jussi Kupari, Matti S Airaksinen, Stefan Lang, David Bryder, Shamit Soneji, Göran Karlsson & Mikael Sigvardsson, 2018 jul 2, I : Journal of Experimental Medicine. 215, 7, s. 1947-1963 17 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  11. Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

    Jonas Ungerbäck, Hiroyuki Hosokawa, Xun Wang, Tobias Strid, Brian A. Williams, Mikael Sigvardsson & Ellen V. Rothenberg, 2018, I : Genome Research. 28, 10, s. 1508-1519 12 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  12. Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells

    Nicola Guzzi, Maciej Cieśla, Phuong Cao Thi Ngoc, Stefan Lang, Sonali Arora, Marios Dimitriou, Kristyna Pimková, Mikael N.E. Sommarin, Roberto Munita, Michal Lubas, Yiting Lim, Kazuki Okuyama, Shamit Soneji, Göran Karlsson, Jenny Hansson, Göran Jönsson, Anders H. Lund, Mikael Sigvardsson, Eva Hellström-Lindberg, Andrew C. Hsieh & 1 andra, Cristian Bellodi, 2018, I : Cell. 173, 5, s. 1204-1216.e26

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  13. 2017
  14. Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

    Göran Karlsson, Mikael Sigvardsson & Charlotta Böiers, 2017 dec 15, I : EMBO Journal. 36, 24, s. 3552-3554 3 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  15. EZH2 regulates the developmental timing of effectors of the pre-Antigen receptor checkpoints

    Jennifer A. Jacobsen, Jennifer Woodard, Malay Mandal, Marcus R. Clark, Elizabeth T. Bartom, Mikael Sigvardsson & Barbara L. Kee, 2017 jun 15, I : Journal of Immunology. 198, 12, s. 4682-4691 10 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  16. Cellular plasticity in B-cell leukemia

    Rajesh Somasundaram, Tobias Strid & Mikael Sigvardsson, 2017, I : Cell Cycle. 16, 6, s. 495-496 2 s.

    Forskningsoutput: TidskriftsbidragDebate/Note/Editorial

  17. 2016
  18. Clonal conversion of B lymphoid leukemia reveals cross-lineage transfer of malignant states

    Rajesh Somasundaram, Josefine Åhsberg, Kazuki Okuyama, Jonas Ungerbäck, Henrik Lilljebjörn, Thoas Fioretos, Tobias Strid & Mikael Sigvardsson, 2016 nov 15, I : Genes and Development. 30, 22, s. 2486-2499 14 s.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  19. Exploring the multifaceted nature of the common lymphoid progenitor compartment.

    Christina Jensen, Tobias Strid & Mikael Sigvardsson, 2016, I : Current Opinion in Immunology. 39, s. 121-126

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  20. 2015
  21. A novel Lin-CD34+CD38-integrin α2- bipotential megakaryocyte-erythrocyte progenitor population in human bone marrow.

    Wan Man Wong, M Dolinska, Mikael Sigvardsson, Marja Ekblom & H Qian, 2015, I : Leukemia. 30, s. 1399-1402

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  22. Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency.

    Mahadesh A J Prasad, Jonas Ungerbäck, Josefine Åhsberg, Rajesh Somasundaram, Tobias Strid, Malin Larsson, Robert Månsson, Ayla De Paepe, Henrik Lilljebjörn, Thoas Fioretos, James Hagman & Mikael Sigvardsson, 2015, I : Blood. 125, 26, s. 4052-4059

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  23. 2013
  24. An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

    Martin Wahlestedt, Gudmundur Norddahl, Gerd Sten, Amol Ugale, Mary-Ann Micha Frisk, Ragnar Mattsson, Tomas Deierborg, Mikael Sigvardsson & David Bryder, 2013, I : Blood. 121, 21, s. 4257-4264

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  25. Expression of Integrin A2 Receptor in Human Cord Blood Cd34+Cd38-Cd90+ Stem Cells Engrafting Long-Term in Nod/Scid-Il2rγ(C) Null Mice.

    Wan Man Wong, Mikael Sigvardsson, Ingbritt Åstrand-Grundström, Donna Hogge, Jonas Larsson, Hong Qian & Marja Ekblom, 2013, I : Stem Cells. 31, 2, s. 360-371

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  26. 2012
  27. Reduced repression of cytokine signaling ameliorates age-induced decline in hematopoietic stem cell function.

    Gudmundur Norddahl, Martin Wahlestedt, Santiago Gisler, Mikael Sigvardsson & David Bryder, 2012, I : Aging Cell.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  28. 2011
  29. Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging.

    Gudmundur Norddahl, Kees-Jan Pronk, Martin Wahlestedt, Gerd Sten, Jens Nygren, Amol Ugale, Mikael Sigvardsson & David Bryder, 2011, I : Cell Stem Cell. 8, 5, s. 499-510

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  30. A dose-dependent role for EBF1 in repressing non-B-cell-specific genes

    Kara Lukin, Scott Fields, Lisa Guerrettaz, Desiree Straign, Valerie Rodriguez, Sasan Zandi, Robert Månsson, John C. Cambier, Mikael Sigvardsson & James Hagman, 2011, I : European Journal of Immunology. 41, 6, s. 1787-1793

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  31. B-lymphocyte commitment: Identifying the point of no return.

    Eva Welinder, Josefine Ahsberg & Mikael Sigvardsson, 2011, I : Seminars in Immunology. 23, s. 335-340

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  32. 2010
  33. Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells.

    Holger Weishaupt, Mikael Sigvardsson & Joanne Attema, 2010, I : Blood. 115, s. 247-256

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  34. Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication

    Jenny Zetterblad, Hong Qian, Sasan Zandi, Robert Månsson, Anna Lagergren, Frida Hansson, David Bryder, Nils Paulsson & Mikael Sigvardsson, 2010, I : BMC Genomics. 11, 108.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  35. Load and lock: the molecular mechanisms of B-lymphocyte commitment.

    Sasan Zandi, David Bryder & Mikael Sigvardsson, 2010, I : Immunological Reviews. 238, 1, s. 47-62

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  36. Nuclear Factor of Activated T Cells Regulates Osteopontin Expression in Arterial Smooth Muscle in Response to Diabetes-Induced Hyperglycemia.

    Lisa Berglund, Anna Zetterqvist, Jenny Öhman, Mikael Sigvardsson, Laura V González Bosc, Maj-Lis Smith, S Albert Salehi, Elisabet Agardh, Gunilla Nordin Fredrikson, Carl-David Agardh, Jan Nilsson, Brian R Wamhoff, Anna Hultgårdh & Maria Gomez, 2010, I : Arteriosclerosis, Thrombosis and Vascular Biology. 30, s. 218-U154

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  37. Shaping up a lineage-lessons from B lymphopoesis.

    David Bryder & Mikael Sigvardsson, 2010, I : Current Opinion in Immunology. Apr 7, s. 148-153

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  38. Single cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

    Robert Månsson, Sasan Zandi, Eva Welinder, Panagiotis Tsapogas, Nobuo Sakaguchi, David Bryder & Mikael Sigvardsson, 2010, I : Blood. 115, 13, s. 2601-2609

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  39. 2008
  40. B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

    Robert Månsson, Sasan Zandi, Kristina Anderson, Inga-Lill Martensson, Sten Eirik W Jacobsen, David Bryder & Mikael Sigvardsson, 2008, I : Blood. 112, 4, s. 1048-1055

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  41. Deciphering developmental stages of adult myelopoiesis.

    Cornelis J Pronk, Joanne Attema, Derrick J Rossi, Mikael Sigvardsson & David Bryder, 2008, I : Cell Cycle. 7, 6, s. 706-713

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  42. EBF1 is essential for B-Lineage priming and establishment of a transcription factor network in common lymphoid progenitors

    Sasan Zandi, Robert Månsson, Panagiotis Tsapogas, Jenny Zetterblad, David Bryder & Mikael Sigvardsson, 2008, I : Journal of Immunology. 181, 5, s. 3364-3372

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  43. Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression.

    Frida Hansson, Jacek Toporski, Robert Månsson, Bertil Johansson, Ulrika Norén-Nyström, Sten Eirik W Jacobsen, Thomas Wiebe, Marcus Larsson, Mikael Sigvardsson & Anders Castor, 2008, I : Molecular Cancer. 7, 67.

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  44. Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets

    Julia Rolf, Emma Berntman, Martin Stenström, Emma Smith, Robert Månsson, Hanna Stenstad, Tetsuya Yamagata, William Agace, Mikael Sigvardsson & Susanna Cardell, 2008, I : Molecular Immunology. 45, 9, s. 2607-2620

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  45. Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T cell development

    Christina Jensen, Charlotta Böiers, Shabnam Kharazi, Anna Lübking, Tobias Rydén, Mikael Sigvardsson, Ewa Sitnicka Quinn & Sten Eirik W Jacobsen, 2008, I : Blood. 111, 4, s. 2083-2090

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  46. 2007
  47. A critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.

    Maria A Jimenez, Peter Akerblad, Mikael Sigvardsson & Evan D Rosen, 2007, I : Molecular and Cellular Biology. 27, Oct 23, s. 743-757

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  48. Critical role of FLT3 ligand in IL-7 receptor-independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors

    Ewa Sitnicka Quinn, Natalija Buza-Vidas, Henrik Ahlenius, Corrado Cilio, Christos Gekas, Jens Nygren, Robert Månsson, Min Cheng, Christina Jensen, Marcus Svensson Frej, Karin Leandersson, William Agace, Mikael Sigvardsson & Sten Eirik W Jacobsen, 2007, I : Blood. 110, 8, s. 2955-2964

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  49. Ectopic expression of PAX5 promotes self renewal of bi-phenotypic myeloid progenitors co-expressing myeloid and B-cell lineage associated genes.

    Kristina Anderson, Corinne Rusterholz, Robert Månsson, Christina Jensen, Karl Bacos, Sasan Zandi, Yutaka Sasaki, Claus Nerlov, Mikael Sigvardsson & Sten Eirik W Jacobsen, 2007, I : Blood. 109, Jan 11, s. 3697-3705

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  50. Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy

    Cornelis J. H. Pronk, Derrick J. Rossi, Robert Månsson, Joanne Attema, Gudmundur Norddahl, Charles Kwok Fai Chan, Mikael Sigvardsson, Irving L. Weissman & David Bryder, 2007, I : Cell Stem Cell. 1, 4, s. 428-442

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  51. HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.

    Mattias Magnusson, Ann Brun, Noriko Miyake, Jonas Larsson, Mats Ehinger, Jon Mar Björnsson, Anton Wutz, Mikael Sigvardsson & Stefan Karlsson, 2007, I : Blood. 109, 9, s. 3687-3696

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  52. Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.

    Pontus Holm, Michael T Mader, Nicole Haubst, Andrea Wizenmann, Mikael Sigvardsson & Magdalena Gotz, 2007, I : Molecular and Cellular Neuroscience. 34, 1, s. 99-119

    Forskningsoutput: TidskriftsbidragÖversiktsartikel

  53. Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis

    Andreas Lietz, Martin Janz, Mikael Sigvardsson, Franziska Jundt, Bernd Doerken & Stephan Mathas, 2007, I : British Journal of Haematology. 137, 4, s. 342-348

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  54. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.

    Robert Månsson, Anne Hultquist, Sidinh Luc, Liping Yang, Kristina Anderson, Shabnam Kharazi, Suleiman Al-Hashmi, Karina Liuba, Lina Thorén, Jörgen Adolfsson, Natalija Buza-Vidas, Hong Qian, Shamit Soneji, Tariq Enver, Mikael Sigvardsson & Sten Eirik W Jacobsen, 2007, I : Immunity. 26, 4, s. 407-419

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  55. The CD53 and CEACAM-1 genes are genetic targets for early B cell factor.

    Robert Månsson, Anna Lagergren, Frida Hansson, Emma Smith & Mikael Sigvardsson, 2007, I : European Journal of Immunology. 37, 5, s. 1365-1376

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  56. The CXCL12, periostin and CCL9 genes are direct targets for early B-cell factor (EBF) in OP-9 stroma cells.

    Anna Lagergren, Robert Månsson, Jenny Zetterblad, Emma Smith, Barbro Basta, David Bryder, Peter Akerblad & Mikael Sigvardsson, 2007, I : Journal of Biological Chemistry. 282, 19, s. 14454-14462

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  57. The molecular signature of MDS stem cells supports a stem-cell origin of 5q - myelodysplastic syndromes

    Lars Nilsson, Patrik Edén, Eleonor Olsson, Robert Månsson, Ingbritt Åstrand-Grundström, Bodil Strömbeck, Kim Theilgaard-Moench, Kristina Anderson, Robert Hast, Eva Hellström, Jan Samuelsson, Goesta Bergh, Claus Nerlov, Bertil Johansson, Mikael Sigvardsson, Åke Borg & Sten Eirik W Jacobsen, 2007, I : Blood. 110, 8, s. 3005-3014

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

  58. 2006
  59. Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis.

    Changbin Shi, Xia Zhao, Anna Lagergren, Mikael Sigvardsson, Xiangdong Wang & Roland Andersson, 2006, I : Scandinavian Journal of Gastroenterology. 41, 4, s. 472-480

    Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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