Hemophilia – intracranial hemorrhage

Projekt: Forskning

Forskningsområden

Ämnesklassifikation (UKÄ)

  • Pediatrik

Beskrivning

The general aim of this project is to improve the quality of care of children with hemophilia by investigation of the mortality and morbidity caused by intracranial hemorrhage and if it can be improved by the treatment regimen.

The specific aims of this project are to test the hypothesis:
- Primary hypothesis; children on prophylactic treatment rarely develop intracranial hemorrhage in comparison with children on-demand therapy
- Secondary hypothesis; intracranial hemorrhage in children on prophylaxis is caused by a combination of trauma and low factor VIII/IX concentrations
- Secondary hypothesis; intracranial hemorrhage in children on prophylaxis cause less sequele compared to hemorrhages in children without prophylaxis
- To study, by using the PedNet Registry, the frequency and clinical outcome of intracranial hemorrhage in the neonatal period, in patients who have developed neutralizing inhibitors and in patients with moderate/mild hemophilia
StatusEj startat

Participants