Multiparametric mapping of the brain at 7T using gradient echoes

Projekt: ForskningInternationellt samarbete




The versatility and high effiecacy of the 3D spoiled gradient-echo sequence is employed for multi-parametric mapping of the brain at 7T. By variable flip angles (VFA) are used to map the transverse relaxation rate R1=1/T1 and proton density, but also magnetisation transfer (MT) if selective MT-pulses are applied off-resonance prior to excitation. Acquiring multiple gradient echoes yields the effective transverse relaxation rate R2*=1/T2*, besides an increase in SNR in VFA experiments. The signal phase is exploited for mapping the local B0 field, which in turn is modeled by quantitative distribution of susceptibility (qSM).
Kort titelMPM at 7T
Gällande start-/slutdatum2016/11/012020/11/01


  • Lunds universitet (ansvarig)
  • Danish Research Center for Magnetic Resonance, Hvidovre Hospital
  • Max Planck Institute for Human Cognitive and Brain Sciences


Relaterad forskningsoutput

Hampus Olsson, Andersen, M., Ronnie Wirestam, Jimmy Lätt & Gunther Helms, 2020 jan 20, (Accepted/In press) I : Magnetic Resonance in Medicine. 24 s., MRM-19-20726.R1.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Hampus Olsson, Andersen, M., Jimmy Lätt, Ronnie Wirestam & Gunther Helms, 2019 apr 29, Magnetization transfer (MT) of human brain at 7T in the context of a 3D multi-parameter mapping protocol. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 4 s. 309. (Proceedings of the ISMRM; vol. 27).

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceeding

Balteau, E., Tabelow, K., Ashburner, J., Callaghan, M., Draganski, B., Gunther Helms, Kherif, F., Leutritz, T., Lutti, A., Philips, C., Reimer, E., Ruthotto, L., Seif, M., Weiskopf, N., Ziegler, G. & Mohammadi, S., 2018 jul 31, Berlin: Weierstraß Institute for Applied Analysis and Stochastics, 35 s.

Forskningsoutput: Working paper

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Relaterade aktiviteter

Helms, G. (Talare), Olsson, H. (medverkande)
2019 sep 292019 okt 2

Aktivitet: Föredrag eller presentationPresentation

Helms, G. (medverkande)
2019 sep 4

Aktivitet: Konsultverksamhet, expertuppdrag och medlemskapMedlem i styrelse/kommitté/råd etc

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