Stroke imaging

Projekt: Forskning

Forskningsområden

Ämnesklassifikation (UKÄ)

  • Radiologi och bildbehandling
  • Neurologi

Beskrivning

Stroke Imaging
Stroke is the second leading cause of death and the leading cause of permanent disability in adults. Genetic factors may contribute up to 50% of the risk for any individual to suffer a stroke. Radiological examinations are pivotal in stroke diagnostics. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) are the main modalities used. Imaging is an essential component to describe the clinical presentation – phenotype - of any stroke.

Formed in 2007, the International Stroke Genetics Consortium (ISGC) is a community of clinicians and investigators devoted to understanding the genetics of cerebrovascular disease and to using new knowledge to improve the lives of people through the prevention and treatment of stroke and its consequences.
As part of the ISGC collaboration an image database has been created to link imaging characteristics to genetics in stroke. To date this image database includes more than 3000 MRI examinations from patients with acute stroke from 12 sites. It thereby constitutes one of the world’s largest imaging material on acute stroke.
During 2016 and 2017 we have reviewed all MRI examinations in the database. Radiological characteristics such as vascular anatomy and pathology, ischemic lesion location and other characteristics have been systematically recorded. During 2017-18 we will analyze aspects of stroke connected to imaging and vascular anatomy. This work will include collaborative projects with professor Natalia Rost and her team at Massachusetts General Hospital/Harvard Medical School.
Our work will further the understanding of stroke in association with vascular anatomy and genetic factors based on one of the largest MRI materials of stroke. This may in the future have implications on diagnosis and follow-up for patients with stroke or TIA.
Our Aims
- To study vascular anatomy in association with acute stroke
- To link imaging characteristics with genetics in stroke
StatusEj startat

Participants