2-Bromoethyl glycosides for synthesis of glycoconjugates on solid support

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

2-Bromoethyl glycosides can easily and in high yields be transformed into sulfones by treatment with a suitable thiol followed by oxidation with mCPBA. The observation that the so formed sulfones were cleaved by treatment with NaOMe/MeOH was used to design a new safety catch linker for synthesis of glycoconjugates on solid support. (C) 2005 Elsevier Ltd. All rights reserved.

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Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Organisk kemi
Originalspråkengelska
Sidor (från-till)2421-2429
TidskriftTetrahedron
Volym61
Utgåva nummer9
StatusPublished - 2005
PublikationskategoriForskning
Peer review utfördJa