A chromosome conformation capture ordered sequence of the barley genome

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title = "A chromosome conformation capture ordered sequence of the barley genome",
abstract = "Cereal grasses of the Triticeae tribe have been the major food source in temperate regions since the dawn of agriculture. Their large genomes are characterized by a high content of repetitive elements and large pericentromeric regions that are virtually devoid of meiotic recombination. Here we present a high-quality reference genome assembly for barley (Hordeum vulgare L.). We use chromosome conformation capture mapping to derive the linear order of sequences across the pericentromeric space and to investigate the spatial organization of chromatin in the nucleus at megabase resolution. The composition of genes and repetitive elements differs between distal and proximal regions. Gene family analyses reveal lineage-specific duplications of genes involved in the transport of nutrients to developing seeds and the mobilization of carbohydrates in grains. We demonstrate the importance of the barley reference sequence for breeding by inspecting the genomic partitioning of sequence variation in modern elite germplasm, highlighting regions vulnerable to genetic erosion.",
keywords = "Plant genetics, DNA sequencing, Natural variation in plants, Agricultural genetics, Hordeum vulgare",
author = "Martin Mascher and Heidrun Gundlach and Axel Himmelbach and Sebastian Beier and Twardziok, {Sven O.} and Thomas Wicker and Volodymyr Radchuk and Christoph Dockter and Hedley, {Pete E.} and Joanne Russell and Micha Bayer and Luke Ramsay and Hui Liu and Georg Haberer and Zhang, {Xiao Qi} and Qisen Zhang and Barrero, {Roberto A.} and Lin Li and Stefan Taudien and Marco Groth and Marius Felder and Alex Hastie and Hana Šimkov{\'a} and Helena Stankov{\'a} and Jan Vr{\'a}na and Saki Chan and Mari{\'a} Mun{\~o}z-Amatria{\'i}n and Rachid Ounit and Steve Wanamaker and Daniel Bolser and Christian Colmsee and Thomas Schmutzer and Lala Aliyeva-Schnorr and Stefano Grasso and Jaakko Tanskanen and Anna Chailyan and Dharanya Sampath and Darren Heavens and Leah Clissold and Sujie Cao and Brett Chapman and Fei Dai and Yong Han and Hua Li and Xuan Li and Chongyun Lin and McCooke, {John K.} and Cong Tan and Penghao Wang and Songbo Wang and Shuya Yin and Gaofeng Zhou and Poland, {Jesse A.} and Bellgard, {Matthew I.} and Ljudmilla Borisjuk and Andreas Houben and Jaroslav Doleael and Sarah Ayling and Stefano Lonardi and Paul Kersey and Peter Langridge and Muehlbauer, {Gary J.} and Clark, {Matthew D.} and Mario Caccamo and Schulman, {Alan H.} and Mayer, {Klaus F. X.} and Matthias Platzer and Close, {Timothy J.} and Uwe Scholz and Mats Hansson and Guoping Zhang and Ilka Braumann and Manuel Spannagl and Chengdao Li and Robbie Waugh and Nils Stein",
year = "2017",
month = "4",
day = "26",
doi = "10.1038/nature22043",
language = "English",
volume = "544",
pages = "427--433",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7651",