A chromosome conformation capture ordered sequence of the barley genome

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Standard

A chromosome conformation capture ordered sequence of the barley genome. / Mascher, Martin; Gundlach, Heidrun; Himmelbach, Axel; Beier, Sebastian; Twardziok, Sven O.; Wicker, Thomas; Radchuk, Volodymyr; Dockter, Christoph; Hedley, Pete E.; Russell, Joanne; Bayer, Micha; Ramsay, Luke; Liu, Hui; Haberer, Georg; Zhang, Xiao Qi; Zhang, Qisen; Barrero, Roberto A.; Li, Lin; Taudien, Stefan; Groth, Marco; Felder, Marius; Hastie, Alex; Šimková, Hana; Stanková, Helena; Vrána, Jan; Chan, Saki; Munõz-Amatriaín, Mariá; Ounit, Rachid; Wanamaker, Steve; Bolser, Daniel; Colmsee, Christian; Schmutzer, Thomas; Aliyeva-Schnorr, Lala; Grasso, Stefano; Tanskanen, Jaakko; Chailyan, Anna; Sampath, Dharanya; Heavens, Darren; Clissold, Leah; Cao, Sujie; Chapman, Brett; Dai, Fei; Han, Yong; Li, Hua; Li, Xuan; Lin, Chongyun; McCooke, John K.; Tan, Cong; Wang, Penghao; Wang, Songbo; Yin, Shuya; Zhou, Gaofeng; Poland, Jesse A.; Bellgard, Matthew I.; Borisjuk, Ljudmilla; Houben, Andreas; Doleael, Jaroslav; Ayling, Sarah; Lonardi, Stefano; Kersey, Paul; Langridge, Peter; Muehlbauer, Gary J.; Clark, Matthew D.; Caccamo, Mario; Schulman, Alan H.; Mayer, Klaus F. X.; Platzer, Matthias; Close, Timothy J.; Scholz, Uwe; Hansson, Mats; Zhang, Guoping; Braumann, Ilka; Spannagl, Manuel; Li, Chengdao; Waugh, Robbie; Stein, Nils.

I: Nature, Vol. 544, Nr. 7651, 26.04.2017, s. 427-433.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Harvard

Mascher, M, Gundlach, H, Himmelbach, A, Beier, S, Twardziok, SO, Wicker, T, Radchuk, V, Dockter, C, Hedley, PE, Russell, J, Bayer, M, Ramsay, L, Liu, H, Haberer, G, Zhang, XQ, Zhang, Q, Barrero, RA, Li, L, Taudien, S, Groth, M, Felder, M, Hastie, A, Šimková, H, Stanková, H, Vrána, J, Chan, S, Munõz-Amatriaín, M, Ounit, R, Wanamaker, S, Bolser, D, Colmsee, C, Schmutzer, T, Aliyeva-Schnorr, L, Grasso, S, Tanskanen, J, Chailyan, A, Sampath, D, Heavens, D, Clissold, L, Cao, S, Chapman, B, Dai, F, Han, Y, Li, H, Li, X, Lin, C, McCooke, JK, Tan, C, Wang, P, Wang, S, Yin, S, Zhou, G, Poland, JA, Bellgard, MI, Borisjuk, L, Houben, A, Doleael, J, Ayling, S, Lonardi, S, Kersey, P, Langridge, P, Muehlbauer, GJ, Clark, MD, Caccamo, M, Schulman, AH, Mayer, KFX, Platzer, M, Close, TJ, Scholz, U, Hansson, M, Zhang, G, Braumann, I, Spannagl, M, Li, C, Waugh, R & Stein, N 2017, 'A chromosome conformation capture ordered sequence of the barley genome', Nature, vol. 544, nr. 7651, s. 427-433. https://doi.org/10.1038/nature22043

APA

Mascher, M., Gundlach, H., Himmelbach, A., Beier, S., Twardziok, S. O., Wicker, T., ... Stein, N. (2017). A chromosome conformation capture ordered sequence of the barley genome. Nature, 544(7651), 427-433. https://doi.org/10.1038/nature22043

CBE

Mascher M, Gundlach H, Himmelbach A, Beier S, Twardziok SO, Wicker T, Radchuk V, Dockter C, Hedley PE, Russell J, Bayer M, Ramsay L, Liu H, Haberer G, Zhang XQ, Zhang Q, Barrero RA, Li L, Taudien S, Groth M, Felder M, Hastie A, Šimková H, Stanková H, Vrána J, Chan S, Munõz-Amatriaín M, Ounit R, Wanamaker S, Bolser D, Colmsee C, Schmutzer T, Aliyeva-Schnorr L, Grasso S, Tanskanen J, Chailyan A, Sampath D, Heavens D, Clissold L, Cao S, Chapman B, Dai F, Han Y, Li H, Li X, Lin C, McCooke JK, Tan C, Wang P, Wang S, Yin S, Zhou G, Poland JA, Bellgard MI, Borisjuk L, Houben A, Doleael J, Ayling S, Lonardi S, Kersey P, Langridge P, Muehlbauer GJ, Clark MD, Caccamo M, Schulman AH, Mayer KFX, Platzer M, Close TJ, Scholz U, Hansson M, Zhang G, Braumann I, Spannagl M, Li C, Waugh R, Stein N. 2017. A chromosome conformation capture ordered sequence of the barley genome. Nature. 544(7651):427-433. https://doi.org/10.1038/nature22043

MLA

Vancouver

Mascher M, Gundlach H, Himmelbach A, Beier S, Twardziok SO, Wicker T et al. A chromosome conformation capture ordered sequence of the barley genome. Nature. 2017 apr 26;544(7651):427-433. https://doi.org/10.1038/nature22043

Author

Mascher, Martin ; Gundlach, Heidrun ; Himmelbach, Axel ; Beier, Sebastian ; Twardziok, Sven O. ; Wicker, Thomas ; Radchuk, Volodymyr ; Dockter, Christoph ; Hedley, Pete E. ; Russell, Joanne ; Bayer, Micha ; Ramsay, Luke ; Liu, Hui ; Haberer, Georg ; Zhang, Xiao Qi ; Zhang, Qisen ; Barrero, Roberto A. ; Li, Lin ; Taudien, Stefan ; Groth, Marco ; Felder, Marius ; Hastie, Alex ; Šimková, Hana ; Stanková, Helena ; Vrána, Jan ; Chan, Saki ; Munõz-Amatriaín, Mariá ; Ounit, Rachid ; Wanamaker, Steve ; Bolser, Daniel ; Colmsee, Christian ; Schmutzer, Thomas ; Aliyeva-Schnorr, Lala ; Grasso, Stefano ; Tanskanen, Jaakko ; Chailyan, Anna ; Sampath, Dharanya ; Heavens, Darren ; Clissold, Leah ; Cao, Sujie ; Chapman, Brett ; Dai, Fei ; Han, Yong ; Li, Hua ; Li, Xuan ; Lin, Chongyun ; McCooke, John K. ; Tan, Cong ; Wang, Penghao ; Wang, Songbo ; Yin, Shuya ; Zhou, Gaofeng ; Poland, Jesse A. ; Bellgard, Matthew I. ; Borisjuk, Ljudmilla ; Houben, Andreas ; Doleael, Jaroslav ; Ayling, Sarah ; Lonardi, Stefano ; Kersey, Paul ; Langridge, Peter ; Muehlbauer, Gary J. ; Clark, Matthew D. ; Caccamo, Mario ; Schulman, Alan H. ; Mayer, Klaus F. X. ; Platzer, Matthias ; Close, Timothy J. ; Scholz, Uwe ; Hansson, Mats ; Zhang, Guoping ; Braumann, Ilka ; Spannagl, Manuel ; Li, Chengdao ; Waugh, Robbie ; Stein, Nils. / A chromosome conformation capture ordered sequence of the barley genome. I: Nature. 2017 ; Vol. 544, Nr. 7651. s. 427-433.

RIS

TY - JOUR

T1 - A chromosome conformation capture ordered sequence of the barley genome

AU - Mascher, Martin

AU - Gundlach, Heidrun

AU - Himmelbach, Axel

AU - Beier, Sebastian

AU - Twardziok, Sven O.

AU - Wicker, Thomas

AU - Radchuk, Volodymyr

AU - Dockter, Christoph

AU - Hedley, Pete E.

AU - Russell, Joanne

AU - Bayer, Micha

AU - Ramsay, Luke

AU - Liu, Hui

AU - Haberer, Georg

AU - Zhang, Xiao Qi

AU - Zhang, Qisen

AU - Barrero, Roberto A.

AU - Li, Lin

AU - Taudien, Stefan

AU - Groth, Marco

AU - Felder, Marius

AU - Hastie, Alex

AU - Šimková, Hana

AU - Stanková, Helena

AU - Vrána, Jan

AU - Chan, Saki

AU - Munõz-Amatriaín, Mariá

AU - Ounit, Rachid

AU - Wanamaker, Steve

AU - Bolser, Daniel

AU - Colmsee, Christian

AU - Schmutzer, Thomas

AU - Aliyeva-Schnorr, Lala

AU - Grasso, Stefano

AU - Tanskanen, Jaakko

AU - Chailyan, Anna

AU - Sampath, Dharanya

AU - Heavens, Darren

AU - Clissold, Leah

AU - Cao, Sujie

AU - Chapman, Brett

AU - Dai, Fei

AU - Han, Yong

AU - Li, Hua

AU - Li, Xuan

AU - Lin, Chongyun

AU - McCooke, John K.

AU - Tan, Cong

AU - Wang, Penghao

AU - Wang, Songbo

AU - Yin, Shuya

AU - Zhou, Gaofeng

AU - Poland, Jesse A.

AU - Bellgard, Matthew I.

AU - Borisjuk, Ljudmilla

AU - Houben, Andreas

AU - Doleael, Jaroslav

AU - Ayling, Sarah

AU - Lonardi, Stefano

AU - Kersey, Paul

AU - Langridge, Peter

AU - Muehlbauer, Gary J.

AU - Clark, Matthew D.

AU - Caccamo, Mario

AU - Schulman, Alan H.

AU - Mayer, Klaus F. X.

AU - Platzer, Matthias

AU - Close, Timothy J.

AU - Scholz, Uwe

AU - Hansson, Mats

AU - Zhang, Guoping

AU - Braumann, Ilka

AU - Spannagl, Manuel

AU - Li, Chengdao

AU - Waugh, Robbie

AU - Stein, Nils

PY - 2017/4/26

Y1 - 2017/4/26

N2 - Cereal grasses of the Triticeae tribe have been the major food source in temperate regions since the dawn of agriculture. Their large genomes are characterized by a high content of repetitive elements and large pericentromeric regions that are virtually devoid of meiotic recombination. Here we present a high-quality reference genome assembly for barley (Hordeum vulgare L.). We use chromosome conformation capture mapping to derive the linear order of sequences across the pericentromeric space and to investigate the spatial organization of chromatin in the nucleus at megabase resolution. The composition of genes and repetitive elements differs between distal and proximal regions. Gene family analyses reveal lineage-specific duplications of genes involved in the transport of nutrients to developing seeds and the mobilization of carbohydrates in grains. We demonstrate the importance of the barley reference sequence for breeding by inspecting the genomic partitioning of sequence variation in modern elite germplasm, highlighting regions vulnerable to genetic erosion.

AB - Cereal grasses of the Triticeae tribe have been the major food source in temperate regions since the dawn of agriculture. Their large genomes are characterized by a high content of repetitive elements and large pericentromeric regions that are virtually devoid of meiotic recombination. Here we present a high-quality reference genome assembly for barley (Hordeum vulgare L.). We use chromosome conformation capture mapping to derive the linear order of sequences across the pericentromeric space and to investigate the spatial organization of chromatin in the nucleus at megabase resolution. The composition of genes and repetitive elements differs between distal and proximal regions. Gene family analyses reveal lineage-specific duplications of genes involved in the transport of nutrients to developing seeds and the mobilization of carbohydrates in grains. We demonstrate the importance of the barley reference sequence for breeding by inspecting the genomic partitioning of sequence variation in modern elite germplasm, highlighting regions vulnerable to genetic erosion.

KW - Plant genetics

KW - DNA sequencing

KW - Natural variation in plants

KW - Agricultural genetics

KW - Hordeum vulgare

UR - http://www.scopus.com/inward/record.url?scp=85018282934&partnerID=8YFLogxK

U2 - 10.1038/nature22043

DO - 10.1038/nature22043

M3 - Article

VL - 544

SP - 427

EP - 433

JO - Nature

T2 - Nature

JF - Nature

SN - 0028-0836

IS - 7651

ER -