A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Objective: Qualitative capillaroscopy patterns in juvenile- and adult-onset systemic sclerosis (SSc) were studied in adulthood using data from the EULAR Scleroderma Trials and Research (EUSTAR) database. Methods: Data collected between June 2004 and April 2013 were examined with focus on capillaroscopy. In this retrospective exploratory study, series of patients with juvenile-onset SSc were matched with series of adult-onset SSc having the same gender and autoantibody profile. Results: 30 of 123 patients with juvenile-onset and 2108 of 7133 with adult-onset SSc had data on capillaroscopy. Juvenile-onset SSc showed scleroderma pattern more frequently than adult-onset SSc (93.3% and 88%). The OR was 2.44 and 95% Cl 0.57-10.41. An active scleroderma pattern was present in 58% of juvenile- and 61% of adult-onset SSc. The OR was 0.91 and 95% Cl 0.28-2.93. The late scleroderma pattern was present in 61% of juvenile- and 55.5% of adult-onset SSc. The OR was 1.06 and 95% Cl 0.34-3.56. Conclusion: This is the first exploratory study on the comparison of capillaroscopy between juvenile- and adult-onset SSc in adulthood. Juvenile-onset SSc had an increase prevalence of sderoderma pattern, but a similar distribution of the three patterns was suggested. Further studies are needed to define this issue. (C) 2015 Elsevier Inc. All rights reserved.

Detaljer

Författare
  • Francesca Ingegnoli
  • Patrizia Boracchi
  • Roberta Gualtierotti
  • Vanessa Smith
  • Maurizio Cutolo
  • Ivan Foeldvari
  • Paolo Airo
  • Juan Jose Alegre-Sancho
  • Yannick Allanore
  • Lidia P. Ananieva
  • Codrina Ancuta
  • Luis Eduardo Andrade
  • Martin Aringer
  • Radim Becvar
  • Mihai Bojinca
  • Irena Butrimiene
  • Francesco Paolo Cantatore
  • Roberto Caporali
  • Paola Caramaschi
  • Patricia E. Carreira
  • Rodica Chirieac
  • Ada Corrado
  • Vanesa Cosentino
  • Giovanna Cuomo
  • Laszlo Czirjak
  • Jose Antonio Pereira Da Silva
  • Paloma Garcia de la Pena Lefebvre
  • Filip De Keyser
  • Carolina de Souza Mueller
  • Kirsten Damgaard
  • Nemanja Damjanov
  • Lev N. Denisov
  • Oliver Distler
  • Alan Doube
  • Alina Dumitrascu
  • Merete Engelhart
  • Marta Valero Exposito
  • Kilian Eyerich
  • Dominique Farge-Bancel
  • Valderilio Feijo Azevedo
  • Rosario Foti
  • Marc Frerix
  • Armando Gabrielli
  • Torhild Garen
  • Paola Gottschalk
  • Laura Groseanu
  • Serena Guiducci
  • Claudia Guenther
  • Eric Hachulla
  • Ruediger Hein
  • Stefan Heitmann
  • Joerg Henes
  • John Highton
  • Florenzo Lannone
  • Ruxandra Maria Ionescu
  • Cristiane Kayser
  • Diana Karpec
  • Eduardo Kerzberg
  • Anna Kotulska
  • Magdalena Kopec-Medrek
  • Eugene Kucharz
  • Brigitte Krummel-Lorenz
  • Felix Lauffer
  • David Launay
  • Mengtao Li
  • Ira Litinsky
  • Esthela Loyo
  • Marco Matucci Cerinic
  • Pierluigi Meroni
  • Oyvind Midtvedt
  • Carmen Marina Mihai
  • Carlomaurizio Montecucco
  • Fabiana Montoya
  • Ewa Morgiel
  • Luc Mouthon
  • Ulf Mueller-Ladner
  • Henrik Nielsen
  • Daniela Opris
  • Vera Ortiz-Santamaria
  • Kati Otsa
  • Margarita Pileckyte
  • Simonetta Pisarri
  • Monica Popescu
  • Maria Rosa Pozzi
  • Francesco Puppo
  • Sebastiao Cezar Radominski
  • Valeria Riccieri
  • Edoardo Rosato
  • Blaz Rozman
  • Silvia Rodriguez Rubio
  • Rita Rugiene
  • Petra Saar
  • Maria Joao Salvador
  • Matthias Seidel
  • Renata Sokolik
  • Kamal Solanki
  • Bojana Stamenkovic
  • Aleksandra Stankovic
  • Simon Stebbings
  • Gitte Strauss
  • Alberto Sulli
  • Szilvia Szamosi
  • Jacek Szechinski
  • Magdalena Szmyrka-Kaczmarek
  • Gabriella Szuecs
  • Cristina-Mihaela Tanaseanu
  • Isabela Tiglea
  • Alan Tyndall
  • Nicola Ughi
  • Maria Uprus
  • Alessandra Vacca
  • Cecilia Varju
  • Algirdas Venalis
  • Paulius Venalis
  • Ulrich A. Walker
  • Malgorzata Widuchowska
  • Piotr Wiland
  • Silvana Zeni
  • Thierry Zenone
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Reumatologi och inflammation

Nyckelord

Originalspråkengelska
Sidor (från-till)19-24
TidskriftMicrovascular Research
Volym102
StatusPublished - 2015
PublikationskategoriForskning
Peer review utfördJa