A novel blood-based biomarker for detection of autism spectrum disorders.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

Abstract

Autism spectrum disorders (ASD) are classified as neurological developmental disorders. Several studies have been carried out to find a candidate biomarker linked to the development of these disorders, but up to date no reliable biomarker is available. Mass spectrometry techniques have been used for protein profiling of blood plasma of children with such disorders in order to identify proteins/peptides that may be used as biomarkers for detection of the disorders. Three differentially expressed peptides with mass-charge (m/z) values of 2020 ± 1, 1864 ± 1 and 1978 ± 1 Da in the heparin plasma of children with ASD that were significantly changed as compared with the peptide pattern of the non-ASD control group are reported here. This novel set of biomarkers allows for a reliable blood-based diagnostic tool that may be used in diagnosis and potentially, in prognosis of ASD

Detaljer

Författare
  • Momeni N
  • Bergquist J
  • Behnia F
  • Bengt Sivberg
  • Joghataei M. T.
  • Persson B. L.
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Hälsovetenskaper
Originalspråkengelska
Sidor (från-till)e91-e91
TidskriftTranslational Psychiatry
Volym2
Utgivningsnummer3
StatusPublished - 2012
PublikationskategoriForskning
Peer review utfördJa

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