A novel t(2;17) in transformation of essential thrombocythemia to acute myelocytic leukemia

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Abstract

A transformation of essential thrombocythemia to acute myelocytic leukemia (AML), myelodysplastic syndrome, or agnogenic myelocytic metaplasia is a relatively rare event. It occurs in 1%-4.5% of all patients with either treated or untreated essential thrombocythemia. Cytogenetic changes in the transformation to AML are common. We report the case of a patient treated for essential thrombocythemia with hydroxyurea for 49 months. He developed AML with a t(2;17), which to our knowledge has not been described in the literature.

Detaljer

Författare
  • Vladimir Lj Lazarevic
  • Dragica Tomin
  • Gradimir M Jankovic
  • Darko Antic
  • Marija Dencic
  • Mirjana Gotic
  • Darinka Boskovic
Externa organisationer
  • Norrland University Hospital
Forskningsområden

Nyckelord

Originalspråkengelska
Sidor (från-till)77-9
Antal sidor3
TidskriftCancer Genetics and Cytogenetics
Volym148
Utgåva nummer1
StatusPublished - 2004 jan 1
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa