Activation and cross-reactivity pattern of a new allergen in adhesive plaster

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Standard

Activation and cross-reactivity pattern of a new allergen in adhesive plaster. / Bergendorff, Ola; Hansson, Christer.

I: Contact Dermatitis, Vol. 42, Nr. 1, 2000, s. 11-17.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

Harvard

Bergendorff, O & Hansson, C 2000, 'Activation and cross-reactivity pattern of a new allergen in adhesive plaster', Contact Dermatitis, vol. 42, nr. 1, s. 11-17. https://doi.org/10.1034/j.1600-0536.2000.042001011.x

APA

Bergendorff, O., & Hansson, C. (2000). Activation and cross-reactivity pattern of a new allergen in adhesive plaster. Contact Dermatitis, 42(1), 11-17. https://doi.org/10.1034/j.1600-0536.2000.042001011.x

CBE

Bergendorff O, Hansson C. 2000. Activation and cross-reactivity pattern of a new allergen in adhesive plaster. Contact Dermatitis. 42(1):11-17. https://doi.org/10.1034/j.1600-0536.2000.042001011.x

MLA

Bergendorff, Ola och Christer Hansson. "Activation and cross-reactivity pattern of a new allergen in adhesive plaster". Contact Dermatitis. 2000, 42(1). 11-17. https://doi.org/10.1034/j.1600-0536.2000.042001011.x

Vancouver

Bergendorff O, Hansson C. Activation and cross-reactivity pattern of a new allergen in adhesive plaster. Contact Dermatitis. 2000;42(1):11-17. https://doi.org/10.1034/j.1600-0536.2000.042001011.x

Author

Bergendorff, Ola ; Hansson, Christer. / Activation and cross-reactivity pattern of a new allergen in adhesive plaster. I: Contact Dermatitis. 2000 ; Vol. 42, Nr. 1. s. 11-17.

RIS

TY - JOUR

T1 - Activation and cross-reactivity pattern of a new allergen in adhesive plaster

AU - Bergendorff, Ola

AU - Hansson, Christer

PY - 2000

Y1 - 2000

N2 - N,N'-disalicylidene-1,2-diaminopropane is a copper inhibitor present in some adhesive plasters, rubber products and gasoline. Upon contact with water it is hydrolyzed to salicylaldehyde and 1,2-diaminopropane. All patients in this study showed positive patch-test reactions to N,N'-disalicylidene-1,2-diaminopropane, and also to 1,2-diaminopropane and ethylenediamine. None reacted to salicylaldehyde. Patch testing with different N,N'-disalicylidene-derivatives showed localization of the amino groups in positions 1 and 2 to be a prerequisite of cross-reactivity to 1,2-diaminopropane and ethylenediamine. An extraction procedure and a high-performance liquid chromatography (HPLC) method for the analysis of adhesive plasters is described. Studies of the hydrolysis of the copper inhibitor at physiological pH showed rapid formation of 1,2-diaminopropane under biomimetic conditions.

AB - N,N'-disalicylidene-1,2-diaminopropane is a copper inhibitor present in some adhesive plasters, rubber products and gasoline. Upon contact with water it is hydrolyzed to salicylaldehyde and 1,2-diaminopropane. All patients in this study showed positive patch-test reactions to N,N'-disalicylidene-1,2-diaminopropane, and also to 1,2-diaminopropane and ethylenediamine. None reacted to salicylaldehyde. Patch testing with different N,N'-disalicylidene-derivatives showed localization of the amino groups in positions 1 and 2 to be a prerequisite of cross-reactivity to 1,2-diaminopropane and ethylenediamine. An extraction procedure and a high-performance liquid chromatography (HPLC) method for the analysis of adhesive plasters is described. Studies of the hydrolysis of the copper inhibitor at physiological pH showed rapid formation of 1,2-diaminopropane under biomimetic conditions.

U2 - 10.1034/j.1600-0536.2000.042001011.x

DO - 10.1034/j.1600-0536.2000.042001011.x

M3 - Article

VL - 42

SP - 11

EP - 17

JO - Contact Dermatitis

JF - Contact Dermatitis

SN - 0105-1873

IS - 1

ER -