Additional transplantation of ex vivo generated megakaryocytic cells after high-dose chemotherapy

Forskningsoutput: TidskriftsbidragLetter

Abstract

The additional transplantation of ex vivo generated hematopoietic (post)-progenitor cells represents a possible approach to ameliorate high-dose chemotherapy induced cytopenia. We investigated the feasibility of the large-scale expansion and transplantation of autologous megakaryocytic cells in four patients with advanced solid tumors. Up to 1,460x10(6) ex vivo generated cells were administered without adverse effects but no clear cut effect on platelet recovery was observed.

Detaljer

Författare
  • Stefan Scheding
  • Markus Bergmannn
  • Gisa Rathke
  • Wichard Vogel
  • Wolfram Brugger
  • Lothar Kanz
Externa organisationer
  • External Organization - Unknown
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Hematologi
Originalspråkengelska
Sidor (från-till)630-631
TidskriftHaematologica
Volym89
Utgivningsnummer5
StatusPublished - 2004
PublikationskategoriForskning
Peer review utfördJa
Externt publiceradJa