Adenosine triphosphatases of thermophilic archaeal double-stranded DNA viruses.

Forskningsoutput: TidskriftsbidragÖversiktsartikel

Abstract

Adenosine triphosphatases (ATPases) of double-stranded (ds) DNA archaeal viruses are structurally related to the AAA+ hexameric helicases and translocases. These ATPases have been implicated in viral life cycle functions such as DNA entry into the host, and viral genome packaging into preformed procapsids. We summarize bioinformatical analyses of a wide range of archaeal ATPases, and review the biochemical and structural properties of those archaeal ATPases that have measurable ATPase activity. We discuss their potential roles in genome delivery into the host, virus assembly and genome packaging in comparison to hexameric helicases and packaging motors from bacteriophages.

Detaljer

Författare
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Cellbiologi
Originalspråkengelska
Artikelnummer37
TidskriftCell & bioscience
Volym4
Utgåva nummerJul 23
StatusPublished - 2014
PublikationskategoriForskning
Peer review utfördJa

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