Adult outcome of social function in adolescent-onset schizophrenia and affective psychosis

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Adult outcome of social function in adolescent-onset schizophrenia and affective psychosis. / Jarbin, Håkan; Ott, Yngve; Von Knorring, Anne-Liis.

I: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 42, Nr. 2, 2003, s. 176-183.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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T1 - Adult outcome of social function in adolescent-onset schizophrenia and affective psychosis

AU - Jarbin, Håkan

AU - Ott, Yngve

AU - Von Knorring, Anne-Liis

PY - 2003

Y1 - 2003

N2 - Objective: To examine and compare the adult outcome in a representative sample of hospitalized adolescent-onset psychoses including occupational and social aspects. Method: A total of 81 patients with a first episode of early-onset psychosis (before age 19 years) presenting to the University Hospital of Lund, Sweden, between 1982 and 1993 were followed up an average of 10.5 years (range 5.1-18.2) after admission. Initial diagnosis was assessed from records and consisted of DSM-IVschizophrenia (n = 32), schizoaffective disorder (n = 7), bipolar disorder (n = 25), and major depressive disorder with psychotic features (n = 17). All could be traced and assigned a major outcome group. Results: Early-onset schizophrenia spectrum disorder suffered a chronic course with a poor outcome in 79% of the cases, while early-onset affective psychosis in 74% showed a good or intermediate outcome. The poor outcome (26%) in the affective group was connected to mental retardation in 7% and to progression to a schizoaffective disorder in 12%. A particularly severe outcome was seen for schizophrenia spectrum patients with a family history of nonaffective psychosis. Conclusions: Early-onset schizophrenia spectrum disorder showed a severe course while affective psychoses had a much more benign functional outcome.

AB - Objective: To examine and compare the adult outcome in a representative sample of hospitalized adolescent-onset psychoses including occupational and social aspects. Method: A total of 81 patients with a first episode of early-onset psychosis (before age 19 years) presenting to the University Hospital of Lund, Sweden, between 1982 and 1993 were followed up an average of 10.5 years (range 5.1-18.2) after admission. Initial diagnosis was assessed from records and consisted of DSM-IVschizophrenia (n = 32), schizoaffective disorder (n = 7), bipolar disorder (n = 25), and major depressive disorder with psychotic features (n = 17). All could be traced and assigned a major outcome group. Results: Early-onset schizophrenia spectrum disorder suffered a chronic course with a poor outcome in 79% of the cases, while early-onset affective psychosis in 74% showed a good or intermediate outcome. The poor outcome (26%) in the affective group was connected to mental retardation in 7% and to progression to a schizoaffective disorder in 12%. A particularly severe outcome was seen for schizophrenia spectrum patients with a family history of nonaffective psychosis. Conclusions: Early-onset schizophrenia spectrum disorder showed a severe course while affective psychoses had a much more benign functional outcome.

KW - affective disorder

KW - schizophrenia

KW - adolescence

KW - psychosis

KW - outcome

U2 - 10.1097/01.CHI.0000024917.60748.54

DO - 10.1097/01.CHI.0000024917.60748.54

M3 - Article

VL - 42

SP - 176

EP - 183

JO - Journal of the American Academy of Child Psychiatry

JF - Journal of the American Academy of Child Psychiatry

SN - 0890-8567

IS - 2

ER -