All-or-none (or something in between) transition of DNA

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Abstract

DNA compaction can be caused by multivalent ions as condensing agents. Both discontinuous (all-or-none) and continuous (pearl-necklace structure) transitions have been observed in experiments as the concentration of the condensing agent was increased. We have investigated the DNA transition by analytical calculations in the infinite-chain limit. A mechanism for pearl-necklace structures could be a combinatorial entropy term, which favours a mixture of globules and coils in a single chain. However, when a surface term is taken into account, it gives rise to a discontinuous transition. We also consider the role of surface charges on the globule.

Detaljer

Författare
  • Yoshikatsu Hayashi
Enheter & grupper
Forskningsområden

Ämnesklassifikation (UKÄ) – OBLIGATORISK

  • Fysik
Originalspråkengelska
Sidor (från-till)536-542
TidskriftEurophysics Letters
Volym68
Utgåva nummer4
StatusPublished - 2004
PublikationskategoriForskning
Peer review utfördJa

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