An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction.

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An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction. / Adner, Mikael; Rose, Andrew C; Zhang, Yaping; Swärd, Karl; Benson, Mikael; Uddman, Rolf; Shankley, Nigel P; Cardell, Lars-Olaf.

I: British Journal of Pharmacology, Vol. 137, Nr. 7, 2002, s. 971-982.

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskrift

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TY - JOUR

T1 - An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFalpha up-regulates 5-HT(2A)-mediated contraction.

AU - Adner, Mikael

AU - Rose, Andrew C

AU - Zhang, Yaping

AU - Swärd, Karl

AU - Benson, Mikael

AU - Uddman, Rolf

AU - Shankley, Nigel P

AU - Cardell, Lars-Olaf

PY - 2002

Y1 - 2002

KW - Dose-Response Relationship

KW - Carbachol: pharmacology

KW - Gene Expression Profiling

KW - Inflammation Mediators: pharmacology

KW - Drug

KW - Muscle

KW - Animal

KW - Muscle Contraction: drug effects

KW - Muscarinic Antagonists: pharmacology

KW - Inbred BALB C

KW - Smooth: drug effects

KW - Receptors

KW - Potassium Chloride: pharmacology

KW - Oligonucleotide Array Sequence Analysis

KW - Organ Culture

KW - Smooth: physiology

KW - Tumor Necrosis Factor: pharmacology

KW - Trachea: physiology

KW - Trachea: metabolism

KW - Non-U.S. Gov't

KW - Trachea: drug effects

KW - Time Factors

KW - Serotonin: drug effects

KW - Support

KW - Serotonin Antagonists: pharmacology

KW - Serotonin Agonists: pharmacology

KW - Serotonin Agents: pharmacology

KW - Serotonin: physiology

KW - Serotonin: pharmacology

KW - Male

KW - Isoproterenol: pharmacology

KW - Mice

KW - Atropine: pharmacology

U2 - 10.1038/sj.bjp.0704928

DO - 10.1038/sj.bjp.0704928

M3 - Article

VL - 137

SP - 971

EP - 982

JO - British Journal of Pharmacology

T2 - British Journal of Pharmacology

JF - British Journal of Pharmacology

SN - 1476-5381

IS - 7

ER -